Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Richard A. Colvin"'
Autor:
Dustin Whitney, Ilya Shestopalov, Maeva Fincker, Marc d’Anjou, Kelly Kral, Marisa Gayron, Francis J. Pierciey, Richard A. Colvin
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 31, Iss , Pp 101155- (2023)
Ex vivo autologous hematopoietic stem cell lentiviral-based gene therapy with betibeglogene autotemcel has been studied in patients with transfusion-dependent β-thalassemia in Phase III clinical trials (HGB-207 and HGB-212), with 90% of patients rea
Externí odkaz:
https://doaj.org/article/66defa76c700452da555b487cb91435f
Autor:
Cheryl L. McDonald, Pankaj Qasba, Daniel G. Anderson, Gang Bao, Richard A. Colvin, Donald B. Kohn, Punam Malik, Michael J. Mitchell, William T. Pu, David J. Rawlings, David A. Williams, Terence R. Flotte
Publikováno v:
Human Gene Therapy. 34:83-89
Autor:
Mark C. Walters, Janet L. Kwiatkowski, John B. Porter, Jennifer Schneiderman, Suradej Hongeng, Andreas E. Kulozik, Marina Cavazzana, Martin G. Sauer, Adrian J. Thrasher, Isabelle Thuret, Ashutosh Lal, John E.J. Rasko, Evangelia Yannaki, Shamshad Ali, Ilya Shestopalov, Maeva Fincker, Richard A. Colvin, Dustin Whitney, Franco Locatelli, Alexis A. Thompson
Publikováno v:
Blood. 140:5355-5357
Autor:
Franco Locatelli, Alexis A. Thompson, Janet L. Kwiatkowski, John B. Porter, Adrian J. Thrasher, Suradej Hongeng, Martin G. Sauer, Isabelle Thuret, Ashutosh Lal, Mattia Algeri, Jennifer Schneiderman, Timothy S. Olson, Ben Carpenter, Persis J. Amrolia, Usanarat Anurathapan, Axel Schambach, Christian Chabannon, Manfred Schmidt, Ivan Labik, Heidi Elliot, Ruiting Guo, Mohammed Asmal, Richard A. Colvin, Mark C. Walters
Publikováno v:
New England Journal of Medicine. 386:415-427
Autor:
Sunita Goyal, John Tisdale, Manfred Schmidt, Julie Kanter, Jennifer Jaroscak, Dustin Whitney, Hans Bitter, Philip D. Gregory, Geoffrey Parsons, Marianna Foos, Ashish Yeri, Maple Gioia, Sarah B. Voytek, Alex Miller, Jessie Lynch, Richard A. Colvin, Melissa Bonner
Publikováno v:
New England Journal of Medicine. 386:138-147
Gene therapy with LentiGlobin for sickle cell disease (bb1111, lovotibeglogene autotemcel) consists of autologous transplantation of a patient's hematopoietic stem cells transduced with the BB305 lentiviral vector that encodes the β
Autor:
Timothy S. Olson, Mark C. Walters, Janet L. Kwiatkowski, John B. Porter, Jennifer Schneiderman, Suradej Hongeng, Andreas E. Kulozik, Marina Cavazzana, Martin G. Sauer, Adrian J. Thrasher, Isabelle Thuret, Ashutosh Lal, John E.J. Rasko, Evangelia Yannaki, Shamshad Ali, Richard A. Colvin, Franco Locatelli, Alexis A. Thompson
Publikováno v:
Transplantation and Cellular Therapy. 29:S291-S292
Autor:
Franco, Locatelli, Alexis A, Thompson, Janet L, Kwiatkowski, John B, Porter, Adrian J, Thrasher, Suradej, Hongeng, Martin G, Sauer, Isabelle, Thuret, Ashutosh, Lal, Mattia, Algeri, Jennifer, Schneiderman, Timothy S, Olson, Ben, Carpenter, Persis J, Amrolia, Usanarat, Anurathapan, Axel, Schambach, Christian, Chabannon, Manfred, Schmidt, Ivan, Labik, Heidi, Elliot, Ruiting, Guo, Mohammed, Asmal, Richard A, Colvin, Mark C, Walters
Publikováno v:
The New England journal of medicine. 386(5)
Betibeglogene autotemcel (beti-cel) gene therapy for transfusion-dependent β-thalassemia contains autologous CD34+ hematopoietic stem cells and progenitor cells transduced with the BB305 lentiviral vector encoding the β-globin (βIn this open-label
Autor:
Ruiting Guo, Andreas E. Kulozik, Alexis A. Thompson, Martin Sauer, Evangelia Yannaki, Weijian Liu, John Porter, Adrian J. Thrasher, Mark C. Walters, Janet L. Kwiatkowski, Franco Locatelli, Isabelle Thuret, Richard A. Colvin, Ashutosh Lal, Suradej Hongeng
Publikováno v:
Transplantation and Cellular Therapy. 27:S112-S114
Autor:
Weijian Liu, Alexis A. Thompson, Janet L. Kwiatkowski, John B. Porter, Mark C. Walters, Ruiting Guo, Andreas E. Kulozik, Isabelle Thuret, Suradej Hongeng, Evangelia Yannaki, Franco Locatelli, Ashutosh Lal, Richard A. Colvin, Adrian J. Thrasher, Martin Sauer
Publikováno v:
Blood. 136:52-54
Introduction Betibeglogene autotemcel (beti-cel; LentiGlobin for β-thalassemia) gene therapy is being evaluated for the treatment of transfusion-dependent β-thalassemia (TDT). Initial positive results of beti-cel in the phase 3 studies, HGB-207 (NC
Autor:
Janet L. Kwiatkowski, Franco Locatelli, Julia Yang, Isabelle Thuret, Alexis A. Thompson, John B. Porter, Richard A. Colvin, Evangelia Yannaki, Martin Sauer, Ashutosh Lal, Adrian J. Thrasher, Dustin Whitney, Suradej Hongeng, Mark C. Walters, Andreas E. Kulozik, John J. Farrell, David H.K. Chui, Alexandria Petrusich
Publikováno v:
Blood. 136:1-3
Introduction We investigated the impact of β-thalassemia genotypes and disease genetic modifiers including HBA and KLF1 genotype and sentinel single-nucleotide polymorphism (SNP) genotypes at 3 major HbF quantitative trait loci (QTL) on clinical out