Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Richard A. Castledine"'
Autor:
Marcos Veguillas Hernando, Jonathan C. Moore, Rowena A. Howie, Richard A. Castledine, Samuel L. Bourne, Gareth N. Jenkins, Peter Licence, Martyn Poliakoff, Michael W. George
Publikováno v:
Organic Process Research & Development. 26:1145-1151
A new continuous-flow process is presented for synthesis of the pharmaceutical intermediate norketamine (5). Our approach has been to take the well-established and industrially applied batch synthetic route to this promising antidepressant precursor
Autor:
Richard A. Castledine, Maliha Uroos, James Dowden, Jonathan Day, Ben McKeever-Abbas, William Lewis
Publikováno v:
ChemInform. 45
Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles (I) proceed in high yields and with good regio- and diastereoselectivity.
Autor:
William Lewis, Jonathan Day, Richard A. Castledine, James Dowden, Maliha Uroos, Ben McKeever-Abbas
Cycloaddition reactions between pyridinium ylides and 3-alkenyl oxindoles that proceed in high yield and with very good regio- and diastereoselectivity are reported. The resulting cycloadducts have the same stereochemistry of biologically active oxin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba19250af40e205e228e858cd5e257d1
https://nottingham-repository.worktribe.com/file/717062/1/Line_102_Alkaloid_inspired_spirocyclic.pdf
https://nottingham-repository.worktribe.com/file/717062/1/Line_102_Alkaloid_inspired_spirocyclic.pdf