Zobrazeno 1 - 10
of 3 029
pro vyhledávání: '"Richard A. ANDERSON"'
Autor:
Gabriele Matilionyte, Grace Forsyth, Jingtao Guo, Michael P. Rimmer, Brian P. Hermann, Richard A. Anderson, Rod T. Mitchell
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Currently there are no established fertility preservation options for pre-pubertal boys facing cancer treatment. Granulocyte-colony stimulating factor (G-CSF) treatment has been proposed to be chemoprotective against spermatogonia
Externí odkaz:
https://doaj.org/article/b30c250c7d104be2b459f638c8170cdc
Autor:
Wanyuan Cui, Kelly-Anne Phillips, Prudence A. Francis, Richard A. Anderson, Ann H. Partridge, Sherene Loi, Sibylle Loibl, Louise Keogh
Publikováno v:
Breast, Vol 64, Iss , Pp 56-62 (2022)
Background: Detailed toxicity data are routinely collected in breast cancer (BC) clinical trials. However, ovarian toxicity is infrequently assessed, despite the adverse impacts on fertility and long-term health from treatment-induced ovarian insuffi
Externí odkaz:
https://doaj.org/article/30f13d9f164f417d8550a7b1180960db
Autor:
Marnie Slonim, Michelle Peate, Kira Merigan, Daniel Lantsberg, Richard A. Anderson, Kate Stern, Debra Gook, Yasmin Jayasinghe
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundFertility preservation is an important healthcare focus in the paediatric and adolescent population when gonadotoxic treatments are required. Ovarian stimulation (OS) resulting in oocyte cryopreservation is a well-established fertility pres
Externí odkaz:
https://doaj.org/article/c827ec5b29a940959bbc3fd779b2227d
Publikováno v:
Frontiers in Endocrinology, Vol 14 (2023)
BackgroundPolycystic ovary syndrome (PCOS) is a heterogeneous disorder, affecting around 10% of women of reproductive age, with infertility, depression or anxiety, obesity, insulin resistance and type 2 diabetes as risk factors. The cause of PCOS is
Externí odkaz:
https://doaj.org/article/1e4bdf00444149db928fd50c078afe1a
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1430 (2023)
The capacity for cancer cells to metastasize to distant organs depends on their ability to execute the carefully choreographed processes of cell adhesion and migration. As most human cancers are of epithelial origin (carcinoma), the transcriptional d
Externí odkaz:
https://doaj.org/article/d81d4d63c839450889705b76efbada8d
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1297 (2023)
Cytoplasmic phosphoinositides (PI) are critical regulators of the membrane–cytosol interface that control a myriad of cellular functions despite their low abundance among phospholipids. The metabolic cycle that generates different PI species is cru
Externí odkaz:
https://doaj.org/article/d7c03967a5dc46f58ebecafc5374fb22
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
BackgroundExposure to chemotherapy during childhood can impair future fertility. Studies using in vitro culture have shown exposure to platinum-based alkylating-like chemotherapy reduces the germ cell number in the human fetal testicular tissues. We
Externí odkaz:
https://doaj.org/article/09aca68f5ae64a9c985dbfd4c571d2ed
Autor:
Georgina L. Jones, Rachael H. Moss, Frances Darby, Neda Mahmoodi, Bob Phillips, Jane Hughes, Katharina S. Vogt, Diana M. Greenfield, Grete Brauten-Smith, Jacqui Gath, Tonia Campbell, Daniel Stark, Galina Velikova, John A. Snowden, Ellissa Baskind, Mariano Mascerenhas, Daniel Yeomanson, Jonathan Skull, Sheila Lane, Hilary L. Bekker, Richard A. Anderson
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundWomen with a new cancer diagnosis face complex decisions about interventions aiming to preserve their fertility. Decision aids are more effective in supporting decision making than traditional information provision. We describe the developm
Externí odkaz:
https://doaj.org/article/ebac6c4a09c44142b4c0cbeef002646c
Autor:
Federica Lopes, Prathima Tholeti, Satish K. Adiga, Richard A. Anderson, Rod T. Mitchell, Norah Spears
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 114-123 (2021)
Chemotherapy can affect testis development of young boys with cancer, reducing the chances of fatherhood in adulthood. Studies using experimental models are needed to determine the damage caused by individual chemotherapy drugs in order to predict th
Externí odkaz:
https://doaj.org/article/d370702363bb46eb9fd9cf95d0b4cafd
Autor:
Melissa D. Tharmalingam, Gabriele Matilionyte, William H. B. Wallace, Jan-Bernd Stukenborg, Kirsi Jahnukainen, Elizabeth Oliver, Anne Goriely, Sheila Lane, Jingtao Guo, Bradley Cairns, Anne Jorgensen, Caroline M. Allen, Federica Lopes, Richard A. Anderson, Norah Spears, Rod T. Mitchell
Publikováno v:
BMC Medicine, Vol 18, Iss 1, Pp 1-16 (2020)
Abstract Background Clinical studies indicate chemotherapy agents used in childhood cancer treatment regimens may impact future fertility. However, effects of individual agents on prepubertal human testis, necessary to identify later risk, have not b
Externí odkaz:
https://doaj.org/article/3ef3b5fe34214194b1c988c0460708f2