Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Richard A Janssen"'
Autor:
Erika N Sutanto, Amelia Scaffidi, Luke W Garratt, Kevin Looi, Clara J Foo, Michela A Tessari, Richard A Janssen, David F Fischer, Stephen M Stick, Anthony Kicic, AREST CF
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191618 (2018)
Mutations in the cystic fibrosis transmembrane regulator (CFTR) gene can reduce function of the CFTR ion channel activity and impair cellular chloride secretion. The gold standard method to assess CFTR function of ion transport using the Ussing chamb
Externí odkaz:
https://doaj.org/article/7ccb2803f8194d08862579e128f80894
Autor:
Diane Bosman-Schluep, Esther C. de Jong, Anaïs Legent, Richard A.J. Janssen, Remko de Pril, Jan Stallen, Banu Verbaken
Publikováno v:
Journal of immunological methods, 494:113058. Elsevier
Inflammatory bowel disease (IBD) is thought to be caused by an aberrant host response to the commensal enteric flora in genetically susceptible individuals. Dendritic cells (DCs) play a key role in the regulation of this response as they sample gut c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a7f669f01b1da497dfa625276867aba
https://doi.org/10.1016/j.jim.2021.113058
https://doi.org/10.1016/j.jim.2021.113058
Autor:
Maté Ongenaert, Elizabeth Smythe, Richard A.J. Janssen, Henriëtte L. Lanz, Andrew R. Wood, Jan Stallen, Edo D. Elstak, Kai S. Erdmann, Sindhu Naik, Paniz Saidiyan
Publikováno v:
International Journal of Molecular Sciences
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5361, p 5361 (2021)
Volume 22
Issue 10
International Journal of Molecular Sciences, Vol 22, Iss 5361, p 5361 (2021)
Lowe syndrome and Dent II disease are X-linked monogenetic diseases characterised by a renal reabsorption defect in the proximal tubules and caused by mutations in the OCRL gene, which codes for an inositol-5-phosphatase. The life expectancy of patie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1a74c7147185d794d1909aada6e0337
https://eprints.whiterose.ac.uk/174740/1/ijms-22-05361-v2.pdf
https://eprints.whiterose.ac.uk/174740/1/ijms-22-05361-v2.pdf
Autor:
Richard A.J. Janssen, Gianluigi Giannelli, Stefano Leporatti, Aránzazu Sánchez, Piero Portincasa, Steven Dooley, Blanca Herrera, Aristidis Moustakas, Wolfgang Mikulits, Peter S. Winter, Isabel Fabregat, Peter ten Dijke
Publikováno v:
European Journal of Clinical Investigation, 46(4), 349-361
Background Transforming growth factor (TGF)-β is a pluripotent cytokine that displays several tissue-specific biological activities. In the liver, TGF-β is considered a fundamental molecule, controlling organ size and growth by limiting hepatocyte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8a41eb1f3e9a328d93a04396195eb50
https://doi.org/10.1111/eci.12596
https://doi.org/10.1111/eci.12596
Autor:
Amelia K. Scaffidi, David F. Fischer, Kevin Looi, Stephen M. Stick, Clara J. Foo, Luke W. Garratt, Erika N. Sutanto, Michela Tessari, Richard A.J. Janssen, Anthony Kicic
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191618 (2018)
PLoS ONE
PLoS ONE
Background Mutations in the cystic fibrosis transmembrane regulator (CFTR) gene can reduce function of the CFTR ion channel activity and impair cellular chloride secretion. The gold standard method to assess CFTR function of ion transport using the U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d947b6be161ee07990c5ad4bc8339b9e
http://europepmc.org/articles/PMC5779693?pdf=render
http://europepmc.org/articles/PMC5779693?pdf=render
Autor:
Soledad R. Ordonez, Richard A.J. Janssen, Gimano D. Amatngalim, Jamil Aarbiou, Almira Henic, Annemarie N. Lekkerkerker, Maria E. Fuentes, Pieter S. Hiemstra, Renate M. Verhoosel, Jasmijn A. Schrumpf, Henk P. Haagsman, Sriram Sridhar, Esther Dronkers
Publikováno v:
Journal of Innate Immunity, 9(4), 359-374
Antimicrobial proteins and peptides (AMPs) are a central component of the antibacterial activity of airway epithelial cells. It has been proposed that a decrease in antibacterial lung defense contributes to an increased susceptibility to microbial in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f4cf31e0327106f6d77a04d2a1c2a54
https://hdl.handle.net/1887/115623
https://hdl.handle.net/1887/115623
Autor:
Paul W. H. I. Parren, Markus Enzelberger, John M. Lambert, Paul Carter, Mary Reilly, Tim Jones, John McCafferty, David C. Lowe, Mike Clark, Julian Davies, Dimiter S. Dimitrov, Max Vásquez, Isidro Hötzel, Robert G.E. Holgate, Jane A. Gross, Bassil I. Dahiyat, Kerry A. Chester, Matthew P. Baker, Martin Steegmaier, John S. Haurum, Martin J. Glennie, Victoria C. Smith, Dennis R. Burton, Richard A.J. Janssen, Stefan Dübel, Andrew George Popplewell, Hendrik J. Rademaker, Andrew Bradbury, Andreas Plückthun, Herren Wu, Thomas Schirrmann, S. L. Martin, Adam Walker, James S. Huston
Publikováno v:
mAbs, 8(1), 1-9
mAbs
mAbs
An important step in drug development is the assignment of an International Nonproprietary Name (INN) by the World Health Organization (WHO) that provides healthcare professionals with a unique and universally available designated name to identify ea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d55402fa482d0701933474f61cc2ce70
http://hdl.handle.net/1887/106996
http://hdl.handle.net/1887/106996
Autor:
N Henke, Benjamin Weichand, Bernhard Brüne, B Mille-Baker, Andreas Weigert, Richard A.J. Janssen, Stephanie Ley
Publikováno v:
Oncogene. 32:631-640
Tumor-associated macrophages (TAMs) are a major supportive component within neoplasms. Mechanisms of macrophage (MΦ) attraction and differentiation to a tumor-promoting phenotype, which is characterized by pronounced interleukin (IL)-10 production,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c5e8c300e3c37b255ab410651448580
https://doi.org/10.1038/onc.2012.77
https://doi.org/10.1038/onc.2012.77
Autor:
S. Rueb, Pieter F. W. Stouten, Celia Quevedo, Shuning He, Leopoldo Laricchia-Robbio, Ida Paramonov, J. C. Izpisua Belmonte, Richard A.J. Janssen, Sergio Menendez, Suzanne Camus, B. E. Snaar-Jagalska
Publikováno v:
Oncogene; Vol 31
Oncogene
Oncogene
Angiogenesis is essential for development and tumor progression. With the aim of identifying new compound inhibitors of the angiogenesis process, we used an established enhanced green fluorescent protein-transgenic zebrafish line to develop an automa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40edf76471546b0a98209909e1e7bb8b
https://doi.org/10.1038/onc.2011.594
https://doi.org/10.1038/onc.2011.594
Publikováno v:
Recueil des Travaux Chimiques des Pays-Bas. 100:85-94
An empirical method for the calculation of the carbon chemical shifts of allene carbons is developed. The method is successful in predicting the chemical shifts in a wide variety of substituted allenes. The effect of the electronegativity of substitu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7cf7e026f96660f9e360076a384d50c5
https://doi.org/10.1002/recl.19811000303
https://doi.org/10.1002/recl.19811000303