Zobrazeno 1 - 10
of 285
pro vyhledávání: '"Richard A, Prinz"'
Autor:
Tao Ruan, Yuling Sun, Jingting Zhang, Jing Sun, Wei Liu, Richard A. Prinz, Daxin Peng, Xiufan Liu, Xiulong Xu
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-16 (2022)
Ruan et al. investigate the effect of H5N1 infection on the expression of intercellular junction proteins (E-cadherin, Occludin, Claudin-1, and ZO-1), which they find results in reduced expression of these proteins via activation of TAK1, p38, and ER
Externí odkaz:
https://doaj.org/article/e7c07e1699bf4f599096555982cf68dc
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
DNA damage by genotoxic drugs such as gemcitabine and 5-fluorouracil (5-FU) activates the ataxia telangiectasia, mutated (ATM)-Chk pathway and induces the expression of NKG2D ligands such as the MHC class I-related chain A and B (MICA/B). The mechani
Externí odkaz:
https://doaj.org/article/e5d982dda9bd4ef29e09ecd5920e62a8
Publikováno v:
Cell Death and Disease, Vol 12, Iss 5, Pp 1-13 (2021)
Abstract The sonic hedgehog (Shh) pathway is highly activated in a variety of malignancies and plays important roles in tumorigenesis, tumor growth, drug resistance, and metastasis. Our recent study showed that the inhibitors of the Shh pathway such
Externí odkaz:
https://doaj.org/article/0db319dd27bd4cacab61d4a168927c0a
Autor:
Simon A. Holoubek, Erin C. MacKinney, Amna M. Khokar, Kristine M. Kuchta, David J. Winchester, Richard A. Prinz, Tricia A. Moo-Young
Publikováno v:
Journal of Surgical Research. 280:169-178
To determine if treatment and clinical outcomes of adrenocortical carcinoma (ACC) vary by race and insurance status.ACC patients from the National Cancer Database (2004-2017) were reviewed. Race was defined as White versus minority (Black and Hispani
Publikováno v:
Cell Reports, Vol 31, Iss 13, Pp 107801- (2020)
Summary: Influenza A virus (IAV) primarily infects the airway and alveolar epithelial cells and disrupts the intercellular junctions, leading to increased paracellular permeability. Although this pathological change plays a critical role in lung tiss
Externí odkaz:
https://doaj.org/article/0ecd16ba06634e22969ba37009e848df
Autor:
Tricia A. Moo-Young, Kristine Kuchta, Amna M. Khokar, Richard A. Prinz, David J. Winchester, Erin C. MacKinney, Simon A. Holoubek
Publikováno v:
Surgery. 171:203-211
Tall cell and diffuse sclerosing variants of papillary thyroid cancer are associated with aggressive features. Radioactive iodine after total thyroidectomy is poorly studied.Patients ≥18 years in the National Cancer Data Base from 2004 to 2016 with
Publikováno v:
Viruses, Vol 12, Iss 10, p 1141 (2020)
Janus kinase (JAK) inhibitors have been developed as novel immunomodulatory drugs and primarily used for treating rheumatoid arthritis and other inflammatory diseases. Recent studies have suggested that this category of anti-inflammatory drugs could
Externí odkaz:
https://doaj.org/article/7ad23bc668834c81ade7fbea54bbcb38
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Thyroid cancer is the most common malignancy of the endocrine system. The initiation of thyroid cancer is often triggered by a genetic mutation in the phosphortidylinositol-3 kinase (PI3K) or mitogen-activated protein kinase (MAPK) pathway, such as R
Externí odkaz:
https://doaj.org/article/7a73541d1c094c15ac597acc401cc03c
Autor:
Richard A. Prinz, David J. Winchester, David B. Ecanow, Tricia A. Moo-Young, Jacob S. Ecanow, Amna Khokar, Michael D. Bortz
Publikováno v:
The American Journal of Surgery. 221:534-537
Background Scarring and disrupted tissue planes add to already-complex neck anatomy and make localization of nonpalpable pathology difficult in cervical endocrine reoperations. We describe the use of radioactive iodine-125 seed localization (RSL) in
Autor:
Tricia A. Moo-Young, David J. Winchester, Michael D. Bortz, Richard A. Prinz, Kristine Kuchta
Publikováno v:
Surgery. 169:2-6
The eighth edition American Joint Committee on Cancer tumor-node-metastasis staging for well-differentiated thyroid cancers, no longer considers "minimal" extrathyroidal extension for tumor staging. This change prompted us to examine the effect of ex