Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Richard B. Dickinson"'
Autor:
Ting-Ching Wang, Samere Abolghasemzade, Brendan P. McKee, Ishita Singh, Kavya Pendyala, Mohammad Mohajeri, Hailee Patel, Aakansha Shaji, Anna L. Kersey, Kajol Harsh, Simran Kaur, Christina R. Dollahon, Sasanka Chukkapalli, Pushkar P. Lele, Daniel E. Conway, Akhilesh K. Gaharwar, Richard B. Dickinson, Tanmay P. Lele
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Extracellular matrix (ECM) stiffness influences cancer cell fate by altering gene expression. Previous studies suggest that stiffness-induced nuclear deformation may regulate gene expression through YAP nuclear localization. We investigated
Externí odkaz:
https://doaj.org/article/507897aa058a4717b51d68fe1a3bd140
Autor:
Richard B. Dickinson, Tanmay P. Lele
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Introduction: Nuclei have characteristic shapes dependent on cell type, which are critical for proper cell function, and nuclei lose their distinct shapes in multiple diseases including cancer, laminopathies, and progeria. Nuclear shapes result from
Externí odkaz:
https://doaj.org/article/81178f2f37c2450882f129808cd3a696
Autor:
Aditya Katiyar, Jian Zhang, Jyot D. Antani, Yifan Yu, Kelsey L. Scott, Pushkar P. Lele, Cynthia A. Reinhart‐King, Nathan J. Sniadecki, Kyle J. Roux, Richard B. Dickinson, Tanmay P. Lele
Publikováno v:
Advanced Science, Vol 9, Iss 23, Pp n/a-n/a (2022)
Abstract Migrating cells must deform their stiff cell nucleus to move through pores and fibers in tissue. Lamin A/C is known to hinder cell migration by limiting nuclear deformation and passage through confining channels, but its role in nuclear defo
Externí odkaz:
https://doaj.org/article/bf83b99aa12048b0bcbc76d06dbce137
Publikováno v:
APL Bioengineering, Vol 6, Iss 1, Pp 010901-010901-10 (2022)
The cell nucleus is commonly considered to be a stiff organelle that mechanically resists changes in shape, and this resistance is thought to limit the ability of cells to migrate through pores or spread on surfaces. Generation of stresses on the cel
Externí odkaz:
https://doaj.org/article/8bb2f1ebd3d8484fae0104c6da2ce09f
Autor:
Vani Narayanan, Purboja Purkayastha, Bo Yu, Kavya Pendyala, Sasanka Chukkapalli, Jolene I Cabe, Richard B. Dickinson, Daniel E. Conway, Tanmay P Lele
Publikováno v:
Biophysical Journal.
Epithelial cells lining a gland and cells grown in a soft extracellular matrix polarize with apical proteins exposed to the lumen and basal proteins in contact with the extracellular matrix. Alterations to polarity, including an apical-out polarity,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446e97e7863a1a6460c9ca5b96558c43
https://doi.org/10.1016/j.bpj.2023.01.005
https://doi.org/10.1016/j.bpj.2023.01.005
Autor:
Richard B. Dickinson, Tanmay P. Lele
Nuclei have characteristic shapes dependent on cell type, which are critical for proper cell function, and nuclei lose their distinct shapes in multiple diseases including cancer, laminopathies, and progeria. Nuclear shapes result from deformations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca96e0691b369b9b50c4ec2567a73828
https://doi.org/10.1101/2022.09.30.510302
https://doi.org/10.1101/2022.09.30.510302
Autor:
Richard B. Dickinson, Robert S. Bourchier, Sandy M. Smith, Roberta R. Fulthorpe, Ian M. Jones, Shu Yi Shen
Publikováno v:
Botany. 99:337-353
Pale swallow-wort, Vincetoxicum rossicum (Kleopow) Barbar., is an invasive weed in the lower Great Lakes Basin of North America. We investigated the relationship between V. rossicum productivity and several environmental variables across 54 establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::065a9d778b99d88df706076d5e89f75a
https://doi.org/10.1139/cjb-2020-0181
https://doi.org/10.1139/cjb-2020-0181
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0149213 (2016)
During development of the vertebrate neuroepithelium, the nucleus in neural progenitor cells (NPCs) moves from the apex toward the base and returns to the apex (called interkinetic nuclear migration) at which point the cell divides. The fate of the r
Externí odkaz:
https://doaj.org/article/166650fc2f524d1a9fa2331edb3b3f9e
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0151322 (2016)
Microtubules have a persistence length of the order of millimeters in vitro, but inside cells they bend over length scales of microns. It has been proposed that polymerization forces bend microtubules in the vicinity of the cell boundary or other obs
Externí odkaz:
https://doaj.org/article/c1ecd73d4ab3420bbeac2b785b51bc83
Autor:
Aditya Katiyar, Jian Zhang, Jyot D. Antani, Yifan Yu, Kelsey L. Scott, Pushkar P. Lele, Cynthia A. Reinhart-King, Nathan J. Sniadecki, Kyle J. Roux, Richard B. Dickinson, Tanmay P. Lele
Migrating cells must deform their stiff cell nucleus to move through pores and fibers in tissue. Lamin A/C is known to hinder cell migration by limiting nuclear deformation and passage through confining channels, but its role in nuclear deformation a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8743ff9213f75195e4fd5ca998c3be07
https://doi.org/10.1101/2022.03.10.483838
https://doi.org/10.1101/2022.03.10.483838