Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Richard, Sherva"'
Autor:
Zoe E. Neale, Jennifer R. Fonda, Mark W. Miller, Erika J. Wolf, Rui Zhang, Richard Sherva, Kelly M. Harrington, Victoria Merritt, Matthew S. Panizzon, Richard L. Hauger, J. Michael Gaziano, the VA Million Veteran Program, Mark W. Logue
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract Background Posttraumatic stress disorder (PTSD) and traumatic brain injury (TBI) are associated with self-reported problems with cognition as well as risk for Alzheimer’s disease and related dementias (ADRD). Overlapping symptom profiles o
Externí odkaz:
https://doaj.org/article/deba554bad8742d5845318631a672ec6
Autor:
Moonil Kang, Ting Fang Alvin Ang, Sherral A. Devine, Richard Sherva, Shubhabrata Mukherjee, Emily H. Trittschuh, Laura E. Gibbons, Phoebe Scollard, Michael Lee, Seo-Eun Choi, Brandon Klinedinst, Connie Nakano, Logan C. Dumitrescu, Alaina Durant, Timothy J. Hohman, Michael L. Cuccaro, Andrew J. Saykin, Walter A. Kukull, David A. Bennett, Li-San Wang, Richard P. Mayeux, Jonathan L. Haines, Margaret A. Pericak-Vance, Gerard D. Schellenberg, Paul K. Crane, Rhoda Au, Kathryn L. Lunetta, Jesse B. Mez, Lindsay A. Farrer
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background More than 75 common variant loci account for only a portion of the heritability for Alzheimer’s disease (AD). A more complete understanding of the genetic basis of AD can be deduced by exploring associations with AD-related endo
Externí odkaz:
https://doaj.org/article/fe39bfd5b90d4d70a686b48ed5244454
Autor:
Yuanchao Zheng, Kathryn L. Lunetta, Chunyu Liu, Alicia K. Smith, Richard Sherva, Mark W. Miller, Mark W. Logue
Publikováno v:
Epigenetics, Vol 18, Iss 1 (2023)
Differentially methylated regions (DMRs) are genomic regions with methylation patterns across multiple CpG sites that are associated with a phenotype. In this study, we proposed a Principal Component (PC) based DMR analysis method for use with data g
Externí odkaz:
https://doaj.org/article/79108c71b1944b7a825327c3f3d669b0
Autor:
Nathan Gaddis, Ravi Mathur, Jesse Marks, Linran Zhou, Bryan Quach, Alex Waldrop, Orna Levran, Arpana Agrawal, Matthew Randesi, Miriam Adelson, Paul W. Jeffries, Nicholas G. Martin, Louisa Degenhardt, Grant W. Montgomery, Leah Wetherill, Dongbing Lai, Kathleen Bucholz, Tatiana Foroud, Bernice Porjesz, Valgerdur Runarsdottir, Thorarinn Tyrfingsson, Gudmundur Einarsson, Daniel F. Gudbjartsson, Bradley Todd Webb, Richard C. Crist, Henry R. Kranzler, Richard Sherva, Hang Zhou, Gary Hulse, Dieter Wildenauer, Erin Kelty, John Attia, Elizabeth G. Holliday, Mark McEvoy, Rodney J. Scott, Sibylle G. Schwab, Brion S. Maher, Richard Gruza, Mary Jeanne Kreek, Elliot C. Nelson, Thorgeir Thorgeirsson, Kari Stefansson, Wade H. Berrettini, Joel Gelernter, Howard J. Edenberg, Laura Bierut, Dana B. Hancock, Eric Otto Johnson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Opioid addiction (OA) is moderately heritable, yet only rs1799971, the A118G variant in OPRM1, has been identified as a genome-wide significant association with OA and independently replicated. We applied genomic structural equation modeling
Externí odkaz:
https://doaj.org/article/a256dcb979ab4a63979d66feec6d2efc
Autor:
Jiayi Cox, Richard Sherva, Leah Wetherill, Tatiana Foroud, Howard J. Edenberg, Henry R. Kranzler, Joel Gelernter, Lindsay A. Farrer
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Stimulant dependence is heritable, but specific genetic factors underlying the trait have not been identified. A genome-wide association study for stimulant dependence was performed in a discovery cohort of African- (AA) and European-ancestr
Externí odkaz:
https://doaj.org/article/68ea6f00cf104255b0cf977f08fbb4cf
Autor:
Richard Sherva, Congcong Zhu, Leah Wetherill, Howard J. Edenberg, Emma Johnson, Louisa Degenhardt, Arpana Agrawal, Nicholas G. Martin, Elliot Nelson, Henry R. Kranzler, Joel Gelernter, Lindsay A. Farrer
Publikováno v:
Exploration of Medicine, Vol 2, Iss 1, Pp 60-73 (2021)
Aim: Substance use disorders (SUD) result in substantial morbidity and mortality worldwide. Opioids, and to a lesser extent cocaine, contribute to a large percentage of this health burden. Despite their high heritability, few genetic risk loci have b
Externí odkaz:
https://doaj.org/article/96b82b8998444b7e8eabf12da50a9a1b
Autor:
Bryan C. Quach, Michael J. Bray, Nathan C. Gaddis, Mengzhen Liu, Teemu Palviainen, Camelia C. Minica, Stephanie Zellers, Richard Sherva, Fazil Aliev, Michael Nothnagel, Kendra A. Young, Jesse A. Marks, Hannah Young, Megan U. Carnes, Yuelong Guo, Alex Waldrop, Nancy Y. A. Sey, Maria T. Landi, Daniel W. McNeil, Dmitriy Drichel, Lindsay A. Farrer, Christina A. Markunas, Jacqueline M. Vink, Jouke-Jan Hottenga, William G. Iacono, Henry R. Kranzler, Nancy L. Saccone, Michael C. Neale, Pamela Madden, Marcella Rietschel, Mary L. Marazita, Matthew McGue, Hyejung Won, Georg Winterer, Richard Grucza, Danielle M. Dick, Joel Gelernter, Neil E. Caporaso, Timothy B. Baker, Dorret I. Boomsma, Jaakko Kaprio, John E. Hokanson, Scott Vrieze, Laura J. Bierut, Eric O. Johnson, Dana B. Hancock
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
There is strong genetic evidence for cigarette smoking behaviors, yet little is known on nicotine dependence (ND). Here, the authors perform a genome-wide association study on ND in 58,000 smokers, identifying five genome-wide significant loci.
Externí odkaz:
https://doaj.org/article/508c732e509b4270b0f67aeb1af54d38
Autor:
Mark W. Logue, Richard Sherva, Rui Zhang, Kelly Harrington, Jennifer Fonda, Victoria Merritt, Matthew S. Panizzon, Richard L. Hauger, Erika Wolf, Mark Miller
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4478e513ccf61baa238343732d57d8b2
https://doi.org/10.1002/alz.061487
https://doi.org/10.1002/alz.061487
Autor:
Richard Sherva, Rui Zhang, Lindsay A. Farrer, Nathan Sahelijo, Gyungah R Jun, Tori Anglin, Catherine Chanfreau, Kelly Cho, Jennifer Fonda, J. Michael Gaziano, Kelly Harrington, Yuk‐Lam Ho, William S. Kremen, Elizabeth M Litkowski, Julie Lynch, Zoe Neale, Panos Roussos, David E Marra, Jesse B. Mez, Mark Miller, David H Salat, Debby W Tsuang, Erika Wolf, Qing Zeng, Matthew S. Panizzon, Victoria Merritt, Richard L. Hauger, Mark W. Logue
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0dc97d7a0a29cc8dd6727c55bc5a962c
https://doi.org/10.1002/alz.063860
https://doi.org/10.1002/alz.063860
Autor:
Marlene Tejeda, John Farrell, Congcong Zhu, Lee Wetzler, Kathryn L. Lunetta, William S. Bush, Eden R Martin, Li‐San Wang, Gerard D. Schellenberg, Margaret A. Pericak‐Vance, Jonathan L. Haines, Lindsay A. Farrer, Richard Sherva
Publikováno v:
Alzheimer's & Dementia. 18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1050bd3f2a1ec6e0f2c6fd4463316573
https://doi.org/10.1002/alz.065753
https://doi.org/10.1002/alz.065753