Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Richard, Lo"'
Autor:
Shiqi Chung, Apoorva Gogna, Sivanathan Chandramohan, Richard Lo, Farah Gillan Irani, Nanda Venkatanarasimha
Publikováno v:
Proceedings of Singapore Healthcare, Vol 32 (2023)
Background A systematic review of the outcomes of combination therapy using Yttrium 90 radioembolization (Y90) and sorafenib/nivolumab for patients with hepatocellular carcinoma (HCC), with hepatic vein (HV) or inferior vena cava (IVC) invasion. The
Externí odkaz:
https://doaj.org/article/cdab07494a12429b91c40aaa11f7a406
Autor:
Suh Chien Pang, Ru Yu Tan, Edward Choke, Jackie Ho, Kiang Hiong Tay, Apoorva Gogna, Farah G. Irani, Kun Da Zhuang, Luke Toh, Shaun Chan, Pradesh Krishnan, Kristen A. Lee, Sum Leong, Richard Lo, Ankur Patel, Bien Soo Tan, Chow Wei Too, Jasmine Chua, Ren Kwang Alvin Tng, Tjun Yip Tang, Siew Ping Chng, Tze Tec Chong, Hsien Ts’ung Tay, Hao Yun Yap, Julian Wong, Rajesh Babu Dharmaraj, Jun Jie Ng, Anil Gopinathan, Eu Kuang Loh, Shao Jin Ong, Gary Yoong, Jia Sheng Tay, Kay Yuan Chong, Chieh Suai Tan
Publikováno v:
Trials, Vol 22, Iss 1, Pp 1-10 (2021)
Abstract Background Percutaneous transluminal angioplasty is the current standard treatment for arteriovenous fistula (AVF) stenosis. The mid- and long-term patency with plain balloon angioplasty (PBA) is however far from satisfactory. While paclitax
Externí odkaz:
https://doaj.org/article/242d3b68878e4c26989a17473144fb1a
Autor:
Bingfeng Luo, Yuan Yuan, Yifei Zhu, Songwu Liang, Runan Dong, Jian Hou, Ping Li, Yaping Xing, Zhenquan Lu, Richard Lo, Guan-Ming Kuang
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveTo investigate the effects of miRNA-145-5p on the tumor development and progression of prostate cancer (Pca) bone metastasis.MethodsLevels of miRNA-145-5p were assessed by real-time quantitative PCR in PC3 (bone metastatic Pca cells), 22RV1
Externí odkaz:
https://doaj.org/article/b93c570becd84bc385b0dbe206723c0f
Autor:
Pedram Shafiei-Jahani, Benjamin P. Hurrell, Lauriane Galle-Treger, Doumet Georges Helou, Emily Howard, Jacob Painter, Richard Lo, Gavin Lewis, Pejman Soroosh, Omid Akbari
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Group 2 innate lymphoid cells (ILC2s) are immune cells present in adipose tissue that contribute to metabolic homeostasis. Here the authors show that Death Receptor 3 (DR3) engagement on ILC2s ameliorates glucose tolerance, protects against insulin-r
Externí odkaz:
https://doaj.org/article/ccb0b1c8242f4157b1256882b0fb6cb3
PD-1 pathway regulates ILC2 metabolism and PD-1 agonist treatment ameliorates airway hyperreactivity
Autor:
Doumet Georges Helou, Pedram Shafiei-Jahani, Richard Lo, Emily Howard, Benjamin P. Hurrell, Lauriane Galle-Treger, Jacob D. Painter, Gavin Lewis, Pejman Soroosh, Arlene H. Sharpe, Omid Akbari
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
PD-1 is a checkpoint inhibitory immune receptor that restrains proliferation and effector functions of a variety of cells, including ILC2s. Here the authors present a human PD-1 agonist that limits ILC2-dependent allergic airway disease in humanized
Externí odkaz:
https://doaj.org/article/7aaaa31742d140ac9e011cac9002ea8f
Autor:
Lauriane Galle-Treger, Ishwarya Sankaranarayanan, Benjamin P. Hurrell, Emily Howard, Richard Lo, Hadi Maazi, Gavin Lewis, Homayon Banie, Alan L. Epstein, Peisheng Hu, Virender K. Rehan, Frank D. Gilliland, Hooman Allayee, Pejman Soroosh, Arlene H. Sharpe, Omid Akbari
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Type-2 innate lymphoid cells (ILC2s) are an immune population secreting Th2 cytokines playing a role in the regulation of adipose metabolic homeostasis. Here the authors show that engagement of GITR, a member of the TNF superfamily, in activated ILC2
Externí odkaz:
https://doaj.org/article/1c23f79b445447f9ae0cd84879992375
Autor:
Fadel Sayes, Catherine Blanc, Louis S. Ates, Nathalie Deboosere, Mickael Orgeur, Fabien Le Chevalier, Matthias I. Gröschel, Wafa Frigui, Ok-Ryul Song, Richard Lo-Man, Florence Brossier, Wladimir Sougakoff, Daria Bottai, Priscille Brodin, Pierre Charneau, Roland Brosch, Laleh Majlessi
Publikováno v:
Cell Reports, Vol 23, Iss 4, Pp 1072-1084 (2018)
Summary: The pathogenic potential of Mycobacterium tuberculosis largely depends on ESX secretion systems exporting members of the multigenic Esx, Esp, and PE/PPE protein families. To study the secretion and regulation patterns of these proteins while
Externí odkaz:
https://doaj.org/article/1d85853904c84b0698247d51802126df
Autor:
Gavin Lewis, Bowen Wang, Pedram Shafiei Jahani, Benjamin P. Hurrell, Homayon Banie, German R. Aleman Muench, Hadi Maazi, Doumet Georges Helou, Emily Howard, Lauriane Galle-Treger, Richard Lo, Swetha Santosh, Andrew Baltus, Gerrold Bongers, Lani San-Mateo, Frank D. Gilliland, Virender K. Rehan, Pejman Soroosh, Omid Akbari
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Group 2 Innate lymphoid cells (ILC2) contribute significantly to allergic inflammation. However, the role of microbiota on ILC2s remains to be unraveled. Here we show that short chain fatty acids (SCFAs), such as butyrate, derived from fermentation o
Externí odkaz:
https://doaj.org/article/f051906e46cb42208860fc1df5d82ef4
Autor:
Daphné Laubreton, Carole Drajac, Jean-François Eléouët, Marie-Anne Rameix-Welti, Richard Lo-Man, Sabine Riffault, Delphyne Descamps
Publikováno v:
Viruses, Vol 12, Iss 8, p 822 (2020)
Respiratory syncytial virus (RSV) is the prevalent pathogen of lower respiratory tract infections in children. The presence of neonatal regulatory B lymphocytes (nBreg) has been associated with a poor control of RSV infection in human newborns and wi
Externí odkaz:
https://doaj.org/article/536f0264c65748679eff5da5c9ed52f7
Autor:
Sze Huey Tan, George Boon-Bee Goh, Chee Kian Tham, Neslihan A. Kaya, Justina Yick Ching Lam, Chung Yip Chan, Richard Lo, Han Chong Toh, David Tai, Weiwei Zhai, Matthew C.H. Ng, David S.W. Ng, Si Lin Koo, Brian K. P. Goh, Hui Shan Chong, Nanda Venkatanarasimha, Tony Kiat-Hon Lim, Tiffany Hennedige, Choon Hua Thng, Joycelyn Lee, Alexander Y. F. Chung, Hian Liang Huang, Apoorva Gogna, Joe Yeong, Su Pin Choo, F. Irani, Pierce K. H. Chow, Jia Qi Lim, Chow Wei Too, Kelvin Siu Hoong Loke
Publikováno v:
The Lancet Gastroenterology & Hepatology. 6:1025-1035
Summary Background Therapeutic synergism between radiotherapy and immune checkpoint blockade has been observed in preclinical models of hepatocellular carcinoma. We aimed to study the safety and efficacy of sequential radioembolisation with yttrium-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5962243c38386ca730554e5faa52ac2b
https://doi.org/10.1016/s2468-1253(21)00305-8
https://doi.org/10.1016/s2468-1253(21)00305-8