Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Richard, Judson"'
Autor:
Kamel Mansouri, José T. Moreira-Filho, Charles N. Lowe, Nathaniel Charest, Todd Martin, Valery Tkachenko, Richard Judson, Mike Conway, Nicole C. Kleinstreuer, Antony J. Williams
Publikováno v:
Journal of Cheminformatics, Vol 16, Iss 1, Pp 1-18 (2024)
Abstract The rapid increase of publicly available chemical structures and associated experimental data presents a valuable opportunity to build robust QSAR models for applications in different fields. However, the common concern is the quality of bot
Externí odkaz:
https://doaj.org/article/ca62db38853a477f8e316d435cd15cb9
Autor:
Anthony J. F. Reardon, Reza Farmahin, Andrew Williams, Matthew J. Meier, Gregory C. Addicks, Carole L. Yauk, Geronimo Matteo, Ella Atlas, Joshua Harrill, Logan J. Everett, Imran Shah, Richard Judson, Sreenivasa Ramaiahgari, Stephen S. Ferguson, Tara S. Barton-Maclaren
Publikováno v:
Frontiers in Toxicology, Vol 5 (2023)
The growing number of chemicals in the current consumer and industrial markets presents a major challenge for regulatory programs faced with the need to assess the potential risks they pose to human and ecological health. The increasing demand for ha
Externí odkaz:
https://doaj.org/article/96854b10d2a34e91b4c5508eac32b91d
Autor:
Joseph L. Bundy, Richard Judson, Antony J. Williams, Chris Grulke, Imran Shah, Logan J. Everett
Publikováno v:
BioData Mining, Vol 15, Iss 1, Pp 1-27 (2022)
Abstract Background The advent of high-throughput transcriptomic screening technologies has resulted in a wealth of publicly available gene expression data associated with chemical treatments. From a regulatory perspective, data sets that cover a lar
Externí odkaz:
https://doaj.org/article/45f0ba492b9d4425af74642e30de2331
Autor:
Nicolò Aurisano, Olivier Jolliet, Weihsueh A. Chiu, Richard Judson, Suji Jang, Aswani Unnikrishnan, Marissa B. Kosnik, Peter Fantke
Publikováno v:
Aurisano, N, Jolliet, O, Chiu, W A, Judson, R, Jang, S, Unnikrishnan, A, Kosnik, M B & Fantke, P 2023, ' Probabilistic Points of Departure and Reference Doses for Characterizing Human Noncancer and Developmental/Reproductive Effects for 10,145 Chemicals ', Environmental Health Perspectives, vol. 131, no. 3, 37016 . https://doi.org/10.1289/EHP11524
Background: Regulatory toxicity values used to assess and manage chemical risks rely on the determination of the point of departure (POD) for a critical effect, which results from a comprehensive and systematic assessment of available toxicity studie
Autor:
Julia E. Rager, Mark J. Strynar, Shuang Liang, Rebecca L. McMahen, Ann M. Richard, Christopher M. Grulke, John F. Wambaugh, Kristin K. Isaacs, Richard Judson, Antony J. Williams, Jon R. Sobus
Publikováno v:
Environment International, Vol 88, Iss , Pp 269-280 (2016)
There is a growing need in the field of exposure science for monitoring methods that rapidly screen environmental media for suspect contaminants. Measurement and analysis platforms, based on high resolution mass spectrometry (HRMS), now exist to meet
Externí odkaz:
https://doaj.org/article/625d2ddb96514c89b260160e3a91d4a3
Autor:
Laura M. Carlson, Michelle Angrish, Avanti V. Shirke, Elizabeth G. Radke, Brittany Schulz, Andrew Kraft, Richard Judson, Grace Patlewicz, Robyn Blain, Cynthia Lin, Nicole Vetter, Courtney Lemeris, Pamela Hartman, Heidi Hubbard, Xabier Arzuaga, Allen Davis, Laura V. Dishaw, Ingrid L. Druwe, Hillary Hollinger, Ryan Jones, J. Phillip Kaiser, Lucina Lizarraga, Pamela D. Noyes, Michele Taylor, Andrew J. Shapiro, Antony J. Williams, Kristina A. Thayer
Publikováno v:
Environmental health perspectives. 130(5)
Per- and polyfluoroalkyl substances (PFAS) are a large class of synthetic (man-made) chemicals widely used in consumer products and industrial processes. Thousands of distinct PFAS exist in commerce. The 2019 U.S. Environmental Protection Agency (U.S
Autor:
Johanna Nyffeler, Clinton Willis, Felix R. Harris, Laura W. Taylor, Richard Judson, Logan J. Everett, Joshua A. Harrill
Publikováno v:
Toxicology and Applied Pharmacology. 444:116032
The United States Environmental Protection Agency has proposed a tiered testing strategy for chemical hazard evaluation based on new approach methods (NAMs). The first tier includes in vitro profiling assays applicable to many (human) cell types, suc
Autor:
Ly, Ly Pham, Sean, Watford, Prachi, Pradeep, Matthew T, Martin, Russell, Thomas, Richard, Judson, R Woodrow, Setzer, Katie, Paul Friedman
Publikováno v:
Comput Toxicol
New approach methodologies (NAMs) for chemical hazard assessment are often evaluated via comparison to animal studies; however, variability in animal study data limits NAM accuracy. The US EPA Toxicity Reference Database (ToxRefDB) enables considerat
Autor:
Richard Judson
Publikováno v:
ALTEX.