Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Richard, Freifelder"'
Autor:
Brittany A. Broder, Mohammed Bhuiyan, Richard Freifelder, David A. Rotsch, Satish K. Chitneni, Marvin W. Makinen, Chin-Tu Chen
Publikováno v:
Molecules, Vol 29, Iss 4, p 799 (2024)
Bis(acetylacetonato)oxidovanadium(IV) [(VO(acac)2], generally known as vanadyl acetylacetonate, has been shown to be preferentially sequestered in malignant tissue. Vanadium-48 (48V) generated with a compact medical cyclotron has been used to label V
Externí odkaz:
https://doaj.org/article/d92f632bdc4649ce881f2738662e0143
Autor:
Jason P. Meier, Hannah J. Zhang, Richard Freifelder, Mohammed Bhuiyan, Phillip Selman, Megan Mendez, Pavithra H. A. Kankanamalage, Thomas Brossard, Antonino Pusateri, Hsiu-Ming Tsai, Lara Leoni, Sagada Penano, Kaustab Ghosh, Brittany A. Broder, Erica Markiewicz, Amy Renne, Walter Stadler, Ralph Weichselbaum, Jerry Nolen, Chien-Min Kao, Satish K. Chitneni, David A. Rotsch, Russell Z. Szmulewitz, Chin-Tu Chen
Publikováno v:
Molecules, Vol 28, Iss 16, p 6041 (2023)
In the field of nuclear medicine, the β+ -emitting 43Sc and β− -emitting 47Sc are promising candidates in cancer diagnosis and targeted radionuclide therapy (TRT) due to their favorable decay schema and shared pharmacokinetics as a true theranost
Externí odkaz:
https://doaj.org/article/d2d85dab6fef4b49ba4943ebf7d7c673
Autor:
Hannah J. Zhang, Matthew Zammit, Chien-Min Kao, Anitha P. Govind, Samuel Mitchell, Nathanial Holderman, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, Xiaoxi Zhuang, Jogeshwar Mukherjee, Chin-Tu Chen, William N. Green
Publikováno v:
J Neurosci
A question relevant to nicotine addiction is how nicotine and other nicotinic receptor membrane-permeant ligands, such as the anti-smoking drug varenicline (Chantix), distribute in brain. Ligands, like varenicline, with high pKaand high affinity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f4cb8c695d85830f981fd20a41960c
https://europepmc.org/articles/PMC9838697/
https://europepmc.org/articles/PMC9838697/
Autor:
Matthew Zammit, Chien-Min Kao, Hannah J. Zhang, Nathanial Holderman, Samuel Mitchell, Eve Tanios, Vincent Zhang, Mohammed Bhuiyan, Richard Freifelder, William N. Green, Jogeshwar Mukherjee, Chin-Tu Chen
Development of positron emission tomography (PET) radiotracers that bind with high-affinity to α4β2-type nicotinic receptors (α4β2Rs) allows for in vivo investigations of the mechanisms underlying nicotine addiction and smoking cessation. One cha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::57372b3584b0c04b825e7d16b705c8e9
https://doi.org/10.1101/2022.08.05.502975
https://doi.org/10.1101/2022.08.05.502975
Publikováno v:
Physics in medicine and biology. 68(1)
Objective. In this work, the irradiation of natural titanium foils in the beam-stop of a compact medical cyclotron, an IBA CYCLONE 18/9, is simulated to assess the efficacy of using a beam-stop as a target holder, and using two different target geome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e42393062f17dc0059ac8aef7808fdb2
https://pubmed.ncbi.nlm.nih.gov/36571231
https://pubmed.ncbi.nlm.nih.gov/36571231
Autor:
Hsiu-Ming Tsai, Hannah J. Zhang, Raymond E. Moellering, Shaghayegh Fathi, David C McCutcheon, Chin-Tu Chen, Gang Li, Jae Won Chang, Mohammed Bhuiyan, Richard Freifelder, Lara Leoni
Publikováno v:
Angew Chem Int Ed Engl
Herein, we report the development of an 18 F-labeled, activity-based small-molecule probe targeting the cancer-associated serine hydrolase NCEH1. We undertook a focused medicinal chemistry campaign to simultaneously preserve potent and specific NCEH1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e0d894cf34974f958333d2dc1557d9d
https://doi.org/10.1002/anie.202004762
https://doi.org/10.1002/anie.202004762
Autor:
Jae Won Chang, Mohammed Bhuiyan, Hsiu‐Ming Tsai, Hannah J. Zhang, Gang Li, Shaghayegh Fathi, David C. McCutcheon, Lara Leoni, Richard Freifelder, Chin‐Tu Chen, Raymond E. Moellering
Publikováno v:
Angewandte Chemie. 132:15273-15277
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e90d27938d596df29ff438686a271a48
https://doi.org/10.1002/ange.202004762
https://doi.org/10.1002/ange.202004762
Autor:
Inna Gertsenshteyn, Boris Epel, Amandeep Ahluwalia, Heejong Kim, Xiaobing Fan, Eugene Barth, Marta Zamora, Erica Markiewicz, Hsui-Ming Tsai, Subramanian Sundramoorthy, Lara Leoni, John Lukens, Mohammed Bhuiyan, Richard Freifelder, Anna Kucharski, Mihai Giurcanu, Brian Roman, Gregory Karczmar, Chien-Min Kao, Howard Halpern, Chin-Tu Chen
Publikováno v:
European journal of nuclear medicine and molecular imaging. 49(12)
To identify the optimal threshold insup18/supF-fluoromisonidazole (FMISO) PET images to accurately locate tumor hypoxia by using electron paramagnetic resonance imaging (pOsub2/subEPRI) as ground truth for hypoxia, defined by pOsub2/sub[Formula: see
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0a8d754e3211b70055144e21c0c193f
https://pubmed.ncbi.nlm.nih.gov/35792927
https://pubmed.ncbi.nlm.nih.gov/35792927
Autor:
Hannah J. Zhang, Matthew Zammit, Chien-Min Kao, Anitha P Govind, Samuel Mitchell, Nathanial Holderman, Mohammed Bhuiyan, Richard Freifelder, Xiaoxi Zhuang, Jogeshwar Mukherjee, Chin-Tu Chen, William N. Green
A question relevant to nicotine addiction is how nicotine and other nicotinic receptor membranepermeant ligands, such as the anti-smoking drug varenicline (Chantix), distribute in brain. Ligands, like varenicline, with high pKa and high-affinity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::009ea2e310f352fc18f76c765a10212c
https://doi.org/10.1101/2021.12.08.471775
https://doi.org/10.1101/2021.12.08.471775
Autor:
Brittany A. Broder, Mohammed P. Bhuiyan, Richard Freifelder, Hannah J. Zhang, Anna Kucharski, Marvin W. Makinen, David A. Rotsch, Chin-Tu Chen
Publikováno v:
Applied Radiation and Isotopes. 186:110270
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb9278e1c1028591191e6e4608d143fc
https://doi.org/10.1016/j.apradiso.2022.110270
https://doi.org/10.1016/j.apradiso.2022.110270