Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Richard, Czerniak"'
Autor:
Tong Zhu, Makoto Kayama, Sandhya Girish, Vikram Sinha, Akintunde Bello, Atsuhiro Kawaguchi, Richard Czerniak, Lee Nagao
Publikováno v:
Clinical and Translational Science, Vol 14, Iss 1, Pp 102-105 (2021)
The International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) Clinical Pharmacology Leadership Group (CPLG) held its first meeting of Japan‐based representatives at Astellas Pharma headquarters in Tokyo on October 1, 20
Externí odkaz:
https://doaj.org/article/b5d6dd1914364d1fbe41af5b10015f6e
Autor:
Sandeepraj Pusalkar, Swapan K. Chowdhury, Richard Czerniak, Xiaochun Zhu, Yuexian Li, Suresh K. Balani, Diane Ramsden
Publikováno v:
European Journal of Drug Metabolism and Pharmacokinetics. 47:371-386
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d2609436f1ae1ba7572573b89e6a099
https://doi.org/10.1007/s13318-021-00751-8
https://doi.org/10.1007/s13318-021-00751-8
Autor:
Jan Tack, Borislav Vladimirov, Ivo Horny, Chui Fung Chong, Jessica Eisner, Richard Czerniak, Yohei Takanami
Publikováno v:
Neurogastroenterology & Motility. 35
Proton-pump inhibitors (PPIs) are cornerstone treatments for gastro-esophageal reflux disease (GERD); however, evidence suggests that most patients exhibit partial response to PPIs, suggesting the need for novel therapies that can provide an improved
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12f7560229d2e938a514cd831adcb3c8
https://doi.org/10.1111/nmo.14468
https://doi.org/10.1111/nmo.14468
Autor:
Marc Pfister, Richard Czerniak, Yaming Hang, Maria Luisa Sardu, John Maringwa, Majid Vakilynejad, Manasa Vishnubhotla
Publikováno v:
Clinical Pharmacology & Therapeutics. 109:1583-1592
A model-based meta-analysis was performed with reported data from obese subjects and patients with type 2 diabetes (T2DM) to characterize the effects of dipeptidyl peptidase 4 (DPP4) inhibitors, gastric inhibitory polypeptides (GIPs), glucagon-like p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d66c5b71fc14b6704153223b1aa50cc
https://doi.org/10.1002/cpt.2130
https://doi.org/10.1002/cpt.2130
Autor:
Lee M. Nagao, Vikram Sinha, Richard Czerniak, Makoto Kayama, Atsuhiro Kawaguchi, Sandhya Girish, Akintunde Bello, Tong Zhu
Publikováno v:
Clinical and Translational Science
Clinical and Translational Science, Vol 14, Iss 1, Pp 102-105 (2021)
Clinical and Translational Science, Vol 14, Iss 1, Pp 102-105 (2021)
The International Consortium for Innovation and Quality in Pharmaceutical Development (IQ) Clinical Pharmacology Leadership Group (CPLG) held its first meeting of Japan‐based representatives at Astellas Pharma headquarters in Tokyo on October 1, 20
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a068b55e99fdd521e58a066d019195c
https://doi.org/10.1111/cts.12853
https://doi.org/10.1111/cts.12853
Autor:
Sandeepraj, Pusalkar, Swapan K, Chowdhury, Richard, Czerniak, Xiaochun, Zhu, Yuexian, Li, Suresh K, Balani, Diane, Ramsden
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 47(3)
Felcisetrag (previously TAK-954 or TD-8954) is a highly selective and potent 5-HTThe metabolism and victim and perpetrator drug interaction potentials towards cytochrome P450s (CYP) and transporters were determined using in vitro models. The excretio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d29e47f55e0a8848623643c738a68cc8
https://pubmed.ncbi.nlm.nih.gov/35157234
https://pubmed.ncbi.nlm.nih.gov/35157234
Autor:
Richard Czerniak, Blanka Cieslarová, Viera Kupčová, Maria Rosario, Ruth Lock, Cheng Dong, George Dukes
Publikováno v:
Journal of clinical pharmacology. 62(8)
Felcisetrag (formerly known as TAK-954) is a selective serotonin receptor agonist under investigation for use in patients with postoperative gastrointestinal dysfunction. The safety, tolerability, and pharmacokinetics (PK) of intravenous (i.v.) felci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f0dc2f335a01ea9ed7e446e072963c8
https://pubmed.ncbi.nlm.nih.gov/35253917
https://pubmed.ncbi.nlm.nih.gov/35253917
Publikováno v:
British Journal of Clinical Pharmacology. 81:700-712
Aims The aims of the study were to characterize the pharmacokinetics (PK) of alogliptin in healthy and type 2 diabetes mellitus (T2DM) subjects using a population PK approach and to assess the influence of various covariates on alogliptin exposure. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0fd3fe84f363d4266487386ef2669f5
https://doi.org/10.1111/bcp.12853
https://doi.org/10.1111/bcp.12853
Publikováno v:
European journal of drug metabolism and pharmacokinetics. 44(2)
It was recently proposed that CYP-mediated drug–drug interactions (DDIs) of vonoprazan with clopidogrel and prasugrel can attenuate the antiplatelet actions of the latter two drugs. Clopidogrel is metabolized to the pharmacologically active metabol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88251f5e185eb7d338fa6d15122779e2
https://pubmed.ncbi.nlm.nih.gov/30361928
https://pubmed.ncbi.nlm.nih.gov/30361928
Publikováno v:
Diet, Nutrition, and Cancer: A Critical Evaluation ISBN: 9781351071383
This chapter discusses the genotoxic elements in the human food chain in regard to cancers of the stomach, colon, and breast. Broiled and fried foods may be sources of genotoxic carcinogens associated with many of the nutritionally related cancers. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1c14afdd6acdcc390e4c4dcfe48d658
https://doi.org/10.1201/9781351071383-8
https://doi.org/10.1201/9781351071383-8
