Zobrazeno 1 - 10
of 127
pro vyhledávání: '"Richard, Bedlack"'
Autor:
Frances Theunissen, Ryan S. Anderton, Frank L. Mastaglia, Ian James, Richard Bedlack, P. Anthony Akkari
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Neurofilament heavy (NEFH) is one of the critical proteins required for the formation of the neuronal cytoskeleton and polymorphisms in NEFH are reported as a rare cause of sporadic ALS (sALS). In the current study, a candidate tetranucleoti
Externí odkaz:
https://doaj.org/article/1c62f08a480247a1b3de51c3ba7d123a
Autor:
Christine Zizzi, Jamison Seabury, Spencer Rosero, Danae Alexandrou, Ellen Wagner, Jennifer S. Weinstein, Anika Varma, Nuran Dilek, John Heatwole, Joanne Wuu, James Caress, Richard Bedlack, Volkan Granit, Jeffrey M. Statland, Paul Mehta, Michael Benatar, Chad Heatwole
Publikováno v:
EClinicalMedicine, Vol 55, Iss , Pp 101768- (2023)
Summary: Background: As novel therapeutic interventions are being developed and tested in the amyotrophic lateral sclerosis (ALS) population, there is a need to better understand the symptoms and issues that have the greatest impact on the lives of i
Externí odkaz:
https://doaj.org/article/8588de4be3c14594b6b567d84d574240
Publikováno v:
Journal of Clinical Neuromuscular Disease. 24:214-221
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a99ab616e0812a2930224b692ee297ea
https://doi.org/10.1097/cnd.0000000000000438
https://doi.org/10.1097/cnd.0000000000000438
Autor:
Frances Theunissen, Ryan S. Anderton, Frank L. Mastaglia, Loren L. Flynn, Samantha J. Winter, Ian James, Richard Bedlack, Stuart Hodgetts, Sue Fletcher, Steve D. Wilton, Nigel G. Laing, Mandi MacShane, Merrilee Needham, Ann Saunders, Alan Mackay-Sim, Ze’ev Melamed, John Ravits, Don W. Cleveland, P. Anthony Akkari
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
ObjectiveThere is a critical need to establish genetic markers that explain the complex phenotypes and pathogenicity of ALS. This study identified a polymorphism in the Stathmin-2 gene and investigated its association with sporadic ALS (sALS) disease
Externí odkaz:
https://doaj.org/article/906c5968a4af4854868be264d12ff5cc
Autor:
Timothy Fullam, Carmel Armon, Paul Barkhaus, Benjamin Barnes, Morgan Beauchamp, Michael Benatar, Tulio Bertorini, Robert Bowser, Mark Bromberg, Javier Mascias Cadavid, Gregory T. Carter, Mazen Dimachkie, Dave Ennist, Eva L. Feldman, Terry Heiman-patterson, Sartaj Jhooty, Isaac Lund, Christopher Mcdermott, Gary Pattee, Dylan Ratner, Paul Wicks, Richard Bedlack
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. :1-5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d92cab9f7bb5d24f4b696b62e03f6d54
https://doi.org/10.1080/21678421.2023.2171302
https://doi.org/10.1080/21678421.2023.2171302
Publikováno v:
Expert Review of Neurotherapeutics. 23:1-7
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ae6cc42108f4818e95b9feedf49f46
https://doi.org/10.1080/14737175.2023.2174018
https://doi.org/10.1080/14737175.2023.2174018
Autor:
Yuyao Sun, Paul Barkhaus, Benjamin Barnes, Morgan Beauchamp, Michael Benatar, Tulio Bertorini, Mark Bromberg, Gregory T. Carter, Jesse Crayle, Merit Cudkowicz, Mazen Dimachkie, Eva L. Feldman, Timothy Fullam, Terry Heiman-Patterson, Sartaj Jhooty, Isaac Lund, Christopher Mcdermott, Gary Pattee, Kaitlyn Pierce, Dylan Ratner, Paul Wicks, Richard Bedlack
Publikováno v:
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration. :1-5
ALSUntangled reviews alternative and off-label treatments for people living with amyotrophic lateral sclerosis (PALS). Here we review ozone therapy. Ozone therapy has possible mechanisms for slowing ALS progression based on its antioxidant, anti-infl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a1e944d0054c11e176d97af22e1e825
https://doi.org/10.1080/21678421.2022.2145904
https://doi.org/10.1080/21678421.2022.2145904
Autor:
Robert G. Miller, Rongzhen Zhang, Paige M. Bracci, Ari Azhir, Richard Barohn, Richard Bedlack, Michael Benatar, James D. Berry, Merit Cudkowicz, Edward J. Kasarskis, Hiroshi Mitsumoto, Georgios Manousakis, David Walk, Bjorn Oskarsson, Jeremy Shefner, Michael S. McGrath
Publikováno v:
Muscle & Nerve. 66:39-49
ALS is a heterogeneous disease that may be complicated or in part driven by inflammation. NP001, a regulator of macrophage activation, was associated with slowing disease progression in those with higher levels of the plasma inflammatory marker C-rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a331ea922bb51bd6b5ef53118452ab5
https://doi.org/10.1002/mus.27511
https://doi.org/10.1002/mus.27511
Autor:
Susan Woolley, Ray Goetz, Pam Factor-Litvak, Jennifer Murphy, Jonathan Hupf, Diana C. Garofalo, Catherine Lomen-Hoerth, Howard Andrews, Daragh Heitzman, Richard Bedlack, Jonathan Katz, Richard Barohn, Eric Sorenson, Bjorn Oskarsson, Americo Fernandes Filho, Edward Kasarskis, Tahseen Mozaffar, Sharon Nations, Andrea Swenson, Agnes Koczon-Jaremko, Georgia Christodoulou, Hiroshi Mitsumoto
Publikováno v:
Behavioural Neurology, Vol 2019 (2019)
Externí odkaz:
https://doaj.org/article/0f915cbc9d2b4b42a4d525741512d01e
Autor:
Susan Woolley, Ray Goetz, Pam Factor-Litvak, Jennifer Murphy, Jonathan Hupf, Catherine Lomen-Hoerth, Howard Andrews, Daragh Heitzman, Richard Bedlack, Jonathan Katz, Richard Barohn, Eric Sorenson, Bjorn Oskarsson, Americo Fernandes Filho, Edward Kasarskis, Tahseen Mozaffar, Sharon Nations, Andrea Swenson, Agnes Koczon-Jaremko, Georgia Christodoulou, Hiroshi Mitsumoto
Publikováno v:
Behavioural Neurology, Vol 2018 (2018)
Objective. To evaluate longitudinal cognitive/behavioral change over 12 months in participants enrolled in the ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS). Methods. We analyzed data from 294 ALS participants, 134 of whom were studie
Externí odkaz:
https://doaj.org/article/35f6be91ed3046459fe8d22778be5b37