Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Richard, Ahrens"'
Autor:
Asma Nusrat, Catherine Ptaschinski, Amnah Yamani, Taeko K. Noah, Vicky Garcia-Hernandez, Lisa Waggoner, David Wu, Richard Ahrens, Charles A. Parkos, Nicholas W. Lukacs, Simon P. Hogan
Publikováno v:
Mucosal Immunology. 14:135-143
Food-triggered anaphylaxis can encompass a variety of systemic and intestinal symptoms. Murine-based and clinical studies have revealed a role for histamine and H1R and H2R-pathway in the systemic response; however, the molecular processes that regul
Autor:
Amnah, Yamani, David, Wu, Richard, Ahrens, Lisa, Waggoner, Taeko K, Noah, Vicky, Garcia-Hernandez, Catherine, Ptaschinski, Charles A, Parkos, Nicholas W, Lukacs, Asma, Nusrat, Simon P, Hogan
Publikováno v:
Mucosal immunology. 14(1)
Food-triggered anaphylaxis can encompass a variety of systemic and intestinal symptoms. Murine-based and clinical studies have revealed a role for histamine and H1R and H2R-pathway in the systemic response; however, the molecular processes that regul
Autor:
Michael W. Konstan, Theodore G. Liou, Steven D. Strausbaugh, Richard Ahrens, Jamshed F. Kanga, Gavin R. Graff, Kathryn Moffett, Susan L. Millard, Samya Z. Nasr, Édith Siméon, Jean Spénard, Josée Grondin
Publikováno v:
Gastroenterology Research and Practice, Vol 2010 (2010)
Background. Pancreatic enzyme replacement therapy is the standard of care for treatment of malabsorption in patients with cystic fibrosis (CF) and exocrine pancreatic insufficiency (PI). Aim. To evaluate efficacy and safety of a new formulation of pa
Externí odkaz:
https://doaj.org/article/41e884ff55b2428c944000e940ed8c67
Autor:
Noah Lechtzin, Nicole Mayer-Hamblett, Natalie E. West, Sarah Allgood, Ellen Wilhelm, Umer Khan, Moira L. Aitken, Bonnie W. Ramsey, Michael P. Boyle, Peter J. Mogayzel, Ronald L. Gibson, David Orenstein, Carlos Milla, John P. Clancy, Veena Antony, Christopher H. Goss, Lynne Quittell, Patrick A. Flume, Shannon S. Carson, John Conlon, Susan Banks-Schlegel, Kelli Joubran, Elena Mullin, Kathy Seidel, Dionne Howe, Scott Donaldson, Susanna McColley, John Clancy, Elliott Dasenbrook, Karen McCoy, Jerry Nick, Frank Accurso, Richard Ahrens, Joanne Billings
Individuals with cystic fibrosis (CF) experience frequent acute pulmonary exacerbations, which lead to decreased lung function and reduced quality of life.The goal of this study was to determine if an intervention directed toward early detection of p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::245ab9615356b42005eabe7bde64b36d
https://europepmc.org/articles/PMC5694835/
https://europepmc.org/articles/PMC5694835/
Autor:
Jane Sledd, Richard Ahrens, David Wu, Simon P. Hogan, Lisa Waggoner, Ying Ting Tsai, Jeebong Lee, Yui‐Hsi Wang
Publikováno v:
Immunity, Inflammation and Disease
Clinical and experimental evidence indicate that polymorphisms within the interleukin 4 (IL‐4) receptor (IL‐4R) chain are sufficient for altered strength of IL‐4/IL‐13 signaling, leading to an exaggerated allergic inflammatory response and in
Autor:
Richard Ahrens, Simon P. Hogan, Yui-Hsi Wang, Katherine Groschwitz, Heather Osterfeld, Muthuvel Arumugam, David Wu, Fred D. Finkelman, Chun-Yu Chen, Richard T. Strait
Publikováno v:
The American Journal of Pathology. 180:1535-1546
Food-triggered anaphylaxis can encompass a variety of symptoms that affect multiple organ systems and can be life threatening. The molecular distinction between non–life-threatening and life-threatening modes of such anaphylaxis has not yet been de
Autor:
Fred D. Finkelman, Gunnar Pejler, Katherine Groschwitz, Heather Osterfeld, Richard Ahrens, Simon P. Hogan, Xiaonan Han, Magnus Åbrink, Michael F. Gurish
Publikováno v:
Proceedings of the National Academy of Sciences. 106:22381-22386
Altered intestinal barrier function is postulated to be a central predisposing factor to intestinal diseases, including inflammatory bowel diseases and food allergies. However, the mechanisms involved in maintaining homeostatic intestinal barrier int
Autor:
Tara Wilson, Ariel Munitz, Lee A. Denson, Luqman Seidu, Simon P. Hogan, Elizabeth Forbes, James J. Lee, Edgar T. Ballard, Marc E. Rothenberg, Huan Xu, Amanda Waddell, Elizabeth Cohen, Carine Blanchard, Maria Lampinen, Richard Ahrens, Rebecca Carey, Keith F. Stringer, Nancy A. Lee
Publikováno v:
The Journal of Immunology. 181:7390-7399
Clinical studies have demonstrated a link between the eosinophil-selective chemokines, eotaxins (eotaxin-1/CCL11 and eotaxin-2/CCL24), eosinophils, and the inflammatory bowel diseases, Crohn’s disease and ulcerative colitis (UC). However, the cellu
Autor:
Fred D. Finkelman, Elizabeth Cohen, Klaus I. Matthaei, Elizabeth Forbes, Andrew N. J. McKenzie, Katherine Groschwitz, J. Pablo Abonia, Richard T. Strait, Simon P. Hogan, Carine Blanchard, Luqman Seidu, Paul S. Foster, Eric B. Brandt, Marc E. Rothenberg, Richard Ahrens
Publikováno v:
The Journal of Experimental Medicine
Previous mouse and clinical studies demonstrate a link between Th2 intestinal inflammation and induction of the effector phase of food allergy. However, the mechanism by which sensitization and mast cell responses occurs is largely unknown. We demons
Autor:
Marc E. Rothenberg, David Artis, Luqman Seidu, Richard Ahrens, Carine Blanchard, Margaret Karow, George D. Yancopoulos, Simon P. Hogan, Andrew J. Murphy, David M. Valenzuela, Katherine R. Groschwitz, Anil Mishra
Publikováno v:
Journal of Allergy and Clinical Immunology. 118:257-268
Background Resistin-like molecule (RELM) β is a cysteine-rich cytokine expressed in the gastrointestinal tract and implicated in insulin resistance and gastrointestinal nematode immunity; however, its function primarily remains an enigma. Objective