Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Richa Singhania"'
Autor:
Christopher N. Mayhew, Richa Singhania
Publikováno v:
STAR Protocols, Vol 4, Iss 1, Pp 101860- (2023)
Summary: Recent breakthroughs in human stem cell technologies have enabled the generation of 3D brain organoid platforms for modeling human neurodevelopment and disease. Here, we review advances in brain organoid development, approaches for generatin
Externí odkaz:
https://doaj.org/article/53baea77a88945a1aa7926c0bba36bcf
Autor:
Amanda Linkous, Demosthenes Balamatsias, Matija Snuderl, Lincoln Edwards, Ken Miyaguchi, Teresa Milner, Batsheva Reich, Leona Cohen-Gould, Andrew Storaska, Yasumi Nakayama, Emily Schenkein, Richa Singhania, Stefano Cirigliano, Tarig Magdeldin, Ying Lin, Gouri Nanjangud, Kalyani Chadalavada, David Pisapia, Conor Liston, Howard A. Fine
Publikováno v:
Cell Reports, Vol 26, Iss 12, Pp 3203-3211.e5 (2019)
Summary: The prognosis of patients with glioblastoma (GBM) remains dismal, with a median survival of approximately 15 months. Current preclinical GBM models are limited by the lack of a “normal” human microenvironment and the inability of many tu
Externí odkaz:
https://doaj.org/article/f28ebd0f3f8540688e121a8ec45550af
Autor:
Jana McCaskill, Richa Singhania, Melinda Burgess, Rachel Allavena, Sherry Wu, Antje Blumenthal, Nigel AJ McMillan
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 2, Iss C (2013)
RNA interference (RNAi) may provide a therapeutic solution to many pulmonary epithelium diseases. However, the main barrier to the clinical use of RNAi remains the lack of efficient delivery vectors. Research has mainly concentrated on the intranasal
Externí odkaz:
https://doaj.org/article/581bb66844fd485abb14d9aca2d8362b
Autor:
Allison R. Pine, Stefano M. Cirigliano, Richa Singhania, James Nicholson, Bárbara da Silva, Christina S. Leslie, Howard A. Fine
Publikováno v:
Cancer Research. 83:1581-1595
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular states, hin
Autor:
Howard A. Fine, Christina S. Leslie, Bárbara da Silva, James Nicholson, Richa Singhania, Stefano M. Cirigliano, Allison R. Pine
Supplementary Table (Table S1) and Figure Legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::511301121068c10ef80413340aa28b44
https://doi.org/10.1158/0008-5472.22820155
https://doi.org/10.1158/0008-5472.22820155
Autor:
Howard A. Fine, Christina S. Leslie, Bárbara da Silva, James Nicholson, Richa Singhania, Stefano M. Cirigliano, Allison R. Pine
Supplementary Figures (Figures S1-S5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28a98d41fc6378d7d17f7c4b36c3eb39
https://doi.org/10.1158/0008-5472.22746996.v1
https://doi.org/10.1158/0008-5472.22746996.v1
Autor:
Howard A. Fine, Christina S. Leslie, Bárbara da Silva, James Nicholson, Richa Singhania, Stefano M. Cirigliano, Allison R. Pine
The tumor microenvironment is necessary for recapitulating the intratumoral heterogeneity and cell state plasticity found in human primary glioblastoma (GBM). Conventional models do not accurately recapitulate the spectrum of GBM cellular states, hin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a46a448f8ea6c32553ca2fd3db3155b
https://doi.org/10.1158/0008-5472.c.6628632.v1
https://doi.org/10.1158/0008-5472.c.6628632.v1
Autor:
Howard A. Fine, Olivier Elemento, Matija Snuderl, David J. Pisapia, Rohan Ramakrishna, Theodore H. Schwartz, Richa Singhania, Lincoln Edwards, Ken Miyaguchi, Amanda Linkous, Yang Hu, James G. Nicholson, Stefano M. Cirigliano, Allison R. Pine
Supplementary figures and tables with Figure legends.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a0e13a8da6b8a938720fcb87459cd7a
https://doi.org/10.1158/2159-8290.22535305.v1
https://doi.org/10.1158/2159-8290.22535305.v1
Autor:
Howard A. Fine, Olivier Elemento, Matija Snuderl, David J. Pisapia, Rohan Ramakrishna, Theodore H. Schwartz, Richa Singhania, Lincoln Edwards, Ken Miyaguchi, Amanda Linkous, Yang Hu, James G. Nicholson, Stefano M. Cirigliano, Allison R. Pine
Glioblastoma (GBM), an incurable tumor, remains difficult to model and more importantly to treat due to its genetic/epigenetic heterogeneity and plasticity across cellular states. The ability of current tumor models to recapitulate the cellular state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d529285713feb8b2b6b66ad78ffe8879
https://doi.org/10.1158/2159-8290.c.6547825.v1
https://doi.org/10.1158/2159-8290.c.6547825.v1
Autor:
Nigel AJ McMillan, Nicholas Saunders, Peter Mollee, Louise Smith, Brent A. Renyolds, Lynne Chambers, Catherine Cheung, Richa Singhania, Devinder Gill, Melinda Burgess
Supplementary Figure 1 - PDF files 2472K, Expression of cell surface markers throughout CLL PBMC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b90d1dfa08d4e1c5a6887e8b87e9d2c
https://doi.org/10.1158/1078-0432.22448796.v1
https://doi.org/10.1158/1078-0432.22448796.v1