Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Richa K Dave"'
Autor:
Richa K Dave, Marcel E Dinger, Megan Andrew, Marjan Askarian-Amiri, David A Hume, Stuart Kellie
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e68306 (2013)
PTPRJ/CD148 is a tyrosine phosphatase that has tumour suppressor-like activity. Quantitative PCR of various cells and tissues revealed that it is preferentially expressed in macrophage-enriched tissues. Within lymphoid tissues immunohistochemistry re
Externí odkaz:
https://doaj.org/article/55948b746ef44323a41af07ca8017e89
Autor:
Chanel E Smart, Marjan E Askarian Amiri, Ania Wronski, Marcel E Dinger, Joanna Crawford, Dmitry A Ovchinnikov, Ana Cristina Vargas, Lynne Reid, Peter T Simpson, Sarah Song, Christiane Wiesner, Juliet D French, Richa K Dave, Leonard da Silva, Amy Purdon, Megan Andrew, John S Mattick, Sunil R Lakhani, Melissa A Brown, Stuart Kellie
Publikováno v:
PLoS ONE, Vol 7, Iss 7, p e40742 (2012)
The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has been implicated in a range of cancers, including breast cancer, yet little is known about its role in normal breast physiology or in mammary gland tumorigenesis.
Externí odkaz:
https://doaj.org/article/d5eaa5f72a81446caa82d85295dc8909
Autor:
Richa K Dave, Tammy Ellis, Melissa C Toumpas, Jonathan P Robson, Elaine Julian, Christelle Adolphe, Perry F Bartlett, Helen M Cooper, Brent A Reynolds, Brandon J Wainwright
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e14680 (2011)
Hedgehog (Hh) signaling is crucial for the generation and maintenance of both embryonic and adult stem cells, thereby regulating development and tissue homeostasis. In the developing neocortex, Sonic Hedgehog (Shh) regulates neural progenitor cell pr
Externí odkaz:
https://doaj.org/article/eac59c1b93da4648bc18b857abdc1404
Canonical Notch signaling is not required for the growth of Hedgehog pathway-induced medulloblastoma
Publikováno v:
Oncogene. 29:3465-3476
Current treatment for medulloblastoma is successful in more than half of all cases but results in substantial disability in survivors. Accordingly, there is considerable interest in drugs that may target specific signaling pathways activated in the t
Autor:
David A. Hume, Stuart Kellie, Marcel E. Dinger, Megan Andrew, Marjan E. Askarian-Amiri, Richa K. Dave
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e68306 (2013)
Dave, R K, Dinger, M E, Andrew, M, Askarian-Amiri, M, Hume, D A & Kellie, S 2013, ' Regulated Expression of PTPRJ/CD148 and an Antisense Long Noncoding RNA in Macrophages by Proinflammatory Stimuli ', PLoS ONE, vol. 8, no. 6, pp. e68306 . https://doi.org/10.1371/journal.pone.0068306
PLoS ONE, Vol 8, Iss 6, p e68306 (2013)
Dave, R K, Dinger, M E, Andrew, M, Askarian-Amiri, M, Hume, D A & Kellie, S 2013, ' Regulated Expression of PTPRJ/CD148 and an Antisense Long Noncoding RNA in Macrophages by Proinflammatory Stimuli ', PLoS ONE, vol. 8, no. 6, pp. e68306 . https://doi.org/10.1371/journal.pone.0068306
PTPRJ/CD148 is a tyrosine phosphatase that has tumour suppressor-like activity. Quantitative PCR of various cells and tissues revealed that it is preferentially expressed in macrophage-enriched tissues. Within lymphoid tissues immunohistochemistry re
Autor:
Sarah Song, Amy Purdon, Christiane Wiesner, Melissa A. Brown, Sunil R. Lakhani, Marjan E. Askarian Amiri, Juliet D. French, Chanel E. Smart, John S. Mattick, Leonard Da Silva, Dmitry A. Ovchinnikov, Marcel E. Dinger, Richa K. Dave, Megan Andrew, Joanna Crawford, Peter T. Simpson, Stuart Kellie, Lynne Reid, Ana Cristina Vargas, Ania Wronski
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 7, p e40742 (2012)
PLoS ONE, Vol 7, Iss 7, p e40742 (2012)
The protein tyrosine phosphatase receptor J, PTPRJ, is a tumor suppressor gene that has been implicated in a range of cancers, including breast cancer, yet little is known about its role in normal breast physiology or in mammary gland tumorigenesis.
Publikováno v:
Experimental cell research. 315(10)
In macrophages, tyrosine phosphorylation regulates many signalling pathways leading to growth, differentiation, activation, phagocytosis and adhesion. Protein tyrosine phosphatases (PTPs) represent a biochemical counterbalance to the activity of prot
Autor:
Stephen P. Young, Andrew D. Cook, Oliver Haworth, Rachel Bayley, Stuart Kellie, Richa K. Dave, Debbie L. Hardie, Christopher D. Buckley, David A. Rider, Amy J. Naylor
Publikováno v:
Arthritis Research & Therapy
Introduction Monocytic cells play a central role in the aetiology of rheumatoid arthritis, and manipulation of the activation of these cells is an approach currently under investigation to discover new therapies for this and associated diseases. CD14
Autor:
Melissa C. Toumpas, Brent A. Reynolds, Christelle Adolphe, Richa K. Dave, Tammy Ellis, Brandon J. Wainwright, Perry F. Bartlett, Elaine Julian, Jonathan P. Robson, Helen M. Cooper
Publikováno v:
PLoS ONE
PLoS ONE, Vol 6, Iss 2, p e14680 (2011)
PLoS ONE, Vol 6, Iss 2, p e14680 (2011)
Background Hedgehog (Hh) signaling is crucial for the generation and maintenance of both embryonic and adult stem cells, thereby regulating development and tissue homeostasis. In the developing neocortex, Sonic Hedgehog (Shh) regulates neural progeni