Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Rich Wambolt"'
Autor:
Donald McAfee, James D. Johnson, Leonard J. Foster, S. R. Wayne Chen, Edwin D.W. Moore, Parisa Asghari, Nichollas E. Scott, Rich Wambolt, Michael F. Allard, Razvan F. Albu, Jerzy E. Kulpa, Thibault Mayor, Lubos Bohunek, Haoning Cen, Michael J. Bround, Christoph H. Borchers, Jun Han, Marc Pourrier, Roger W. Brownsey, David Fedida
Publikováno v:
The Journal of biological chemistry. 291(45)
Cardiac ryanodine receptor (Ryr2) Ca2+ release channels and cellular metabolism are both disrupted in heart disease. Recently, we demonstrated that total loss of Ryr2 leads to cardiomyocyte contractile dysfunction, arrhythmia, and reduced heart rate.
Autor:
Robin P. da Silva, Angela M. Devlin, Rich Wambolt, Michael F. Allard, Melissa B. Glier, Rika E. Aleliunas, Sarah L Gerrard, René L. Jacobs
Publikováno v:
The FASEB Journal. 29
Autor:
Ashraf Abrahani, Ding An, Girsh Kewalramani, Brian Rodrigues, Sheila M. Innis, Rich Wambolt, Sanjoy Ghosh, Michael F. Allard, Dake Qi, Thomas Pulinilkunnil
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 288:E1120-E1127
Given the importance of lipoprotein lipase (LPL) in cardiac and vascular pathology, the objective of the present study was to investigate whether the β-agonist isoproterenol (Iso) influences cardiac LPL. Incubation of quiescent cardiomyocytes with I
Autor:
Parisa Asghari, Timothy J. Kieffer, Rich Wambolt, Michael F. Allard, Marjolaine Philit, James D. Johnson, Claire Smits, Lubos Bohunek, Edwin D.W. Moore, Kenneth R. Boheler, Edward G. Lakatta, Michael J. Bround
Publikováno v:
Cardiovascular research. 96(3)
Aims The molecular mechanisms controlling heart function and rhythmicity are incompletely understood. While it is widely accepted that the type 2 ryanodine receptor ( Ryr2 ) is the major Ca2+ release channel in excitation–contraction coupling, the
Autor:
Ashraf Abrahani, Dake Qi, Ding An, Roger W. Brownsey, Rich Wambolt, Michael F. Allard, Sanjoy Ghosh, Brian Rodrigues, John Andrew Pospisilik, Thomas Pulinilkunnil
Publikováno v:
Diabetes. 53(7)
Glucocorticoids impair insulin sensitivity. Because insulin resistance is closely linked to increased incidence of cardiovascular diseases and given that metabolic abnormalities have been linked to initiation of heart failure, we examined the acute e
Autor:
Dan S. Luciani, Lubos Bohunek, Farnaz Taghizadeh, James D. Johnson, Jerzy E. Kulpa, Edwin D.W. Moore, Michael J. Bround, Brian Rodrigues, Parisa Asghari, Rich Wambolt, Michael F. Allard, Kenneth R. Boheler, Roger W. Brownsey
Publikováno v:
Canadian Journal of Diabetes. 36:S52
s / Can J Diabetes 36 (2012) S24eS76 S52 (NCS) protocols and lack of predictive biomarkers. We aimed to determine the performance of single and simple combinations of NCS parameters for identification and future prediction of DSP. Methods: 406 partic