TGF-β signalling pathways in different compartments of the lower airways of stable COPD patients

Autor: Di Stefano, A, Sangiorgi, C, Gnemmi, I, Casolari, P, Brun, P, Ricciardolo, FL, Contoli, M, Papi, A, Maniscalco, P, Ruggeri, P, Girbino, G, Cappello, F, Pavlides, S, Guo, Y, Chung, KF, Barnes, PJ, Adcock, IM, Balbi, B, Caramori, G

BACKGROUND: The expression and localization of transforming growth factor-beta (TGF-β) pathway proteins in different compartments of the lower airways of stable COPD patients is unclear. OBJECTIVE: To determine TGF-β pathway protein expression in p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______1032::889164eeeab59c1dbefd09945b625567
http://hdl.handle.net/10044/1/55585

Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD

Autor: Cesare Usai, Fabio Luigi Massimo Ricciardolo, Ian M. Adcock, Paola Brun, Alberto Papi, Gaetano Caramori, A. Di Stefano, Marco Carbone, S Ennio D'Anna, Laura Bristot, Francesca Magno, A. Capelli, Federica Sabatini, Isabella Gnemmi, Kian Fan Chung, Peter J. Barnes, A. Zanini, Bruno Balbi, Marco Contoli

Publikováno v: Thorax 64 (2009): 968–975.
info:cnr-pdr/source/autori:Di Stefano A, Caramori G, Gnemmi I, Contoli M, Bristot L, Capelli A, Ricciardolo FL, Magno F, D'Anna SE, Zanini A, Carbone M, Sabatini F, Usai C, Brun P, Chung KF, Barnes PJ, Papi A, Adcock I, Balbi B./titolo:Association of increased CCL5 and CXCL7 chemokine expression with neutrophil activation in severe stable COPD./doi:/rivista:Thorax/anno:2009/pagina_da:968/pagina_a:975/intervallo_pagine:968–975/volume:64

BACKGROUND: Increased numbers of activated neutrophils have been reported in the bronchial mucosa of patients with stable chronic obstructive pulmonary disease (COPD), particularly in severe disease. OBJECTIVES: To investigate the expression of neutr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d8e9877d9c119b61c2ade6c3d0e8972
https://doi.org/10.1136/thx.2009.113647

Th17 immunity in children with allergic asthma and rhinitis: a pharmacological approach

Autor: Caterina Di Sano, Loredana Riccobono, Angela Marina Montalbano, Giusy Daniela Albano, Pascal Chanez, Anna Bonanno, Giulia Anzalone, Rosalia Gagliardo, Fabio Luigi Massimo Ricciardolo, Stefania La Grutta, Mirella Profita, Mark Gjomarkaj

Publikováno v: PLoS ONE
PLoS ONE, Vol 8, Iss 4, p e58892 (2013)

Th17 cells and IL-17A play a role in the development and progression of allergic diseases. We analyzed the IL-17A levels in sputum supernatants (Ss), nasal wash (NW) and plasma (P) from Healthy Controls (HC) and children with Asthma/Rhinitis. We test

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f84652c6e291cbb54f6143dfb68d6886
http://hdl.handle.net/10447/75835

Bacterial load and related innate immune response in the bronchi of rapid decliners with chronic obstructive pulmonary disease.

Autor: D'Anna SE; Divisione di Pneumologia, Istituti Clinici Scientifici Maugeri, IRCCS, Telese, BN, Italy., Dossena F; Divisione di Pneumologia and Laboratorio di Citoimmunopatologia dell'Apparato Cardio Respiratorio, Istituti Clinici Scientifici Maugeri, IRCCS, Veruno, NO, Italy., Gnemmi I; Divisione di Pneumologia and Laboratorio di Citoimmunopatologia dell'Apparato Cardio Respiratorio, Istituti Clinici Scientifici Maugeri, IRCCS, Veruno, NO, Italy., Brun P; Dipartimento di Medicina Molecolare, Università di Padova, Padova, Italy., Spanevello A; Divisione di Pneumologia, Istituti Clinici Scientifici Maugeri, IRCCS, Tradate, VA, Italy., Carriero V; Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Ospedale Universitario San Luigi Gonzaga , Orbassano, Torino, Italy., Bertolini F; Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Ospedale Universitario San Luigi Gonzaga , Orbassano, Torino, Italy., Maniscalco M; Divisione di Pneumologia, Istituti Clinici Scientifici Maugeri, IRCCS, Telese, BN, Italy; Dipartimento di Medicina e Chirurgia, Università Federico II di Napoli, Napoli, Italy. Electronic address: mauro.maniscalco@icsmaugeri.it., Ricciardolo FL; Dipartimento di Scienze Cliniche e Biologiche, Università di Torino, Ospedale Universitario San Luigi Gonzaga , Orbassano, Torino, Italy., Balbi B; Divisione di Pneumologia and Laboratorio di Citoimmunopatologia dell'Apparato Cardio Respiratorio, Istituti Clinici Scientifici Maugeri, IRCCS, Veruno, NO, Italy., Di Stefano A; Divisione di Pneumologia and Laboratorio di Citoimmunopatologia dell'Apparato Cardio Respiratorio, Istituti Clinici Scientifici Maugeri, IRCCS, Veruno, NO, Italy.

Publikováno v: Respiratory medicine [Respir Med] 2023 Aug-Sep; Vol. 215, pp. 107297. Date of Electronic Publication: 2023 May 27.

A microRNA-21-mediated SATB1/S100A9/NF-κB axis promotes chronic obstructive pulmonary disease pathogenesis.

Autor: Kim RY; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, New South Wales 2007, Australia.; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia., Sunkara KP; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia.; Graduate School of Health, Discipline of Pharmacy, University of Technology Sydney, Sydney, New South Wales 2007, Australia.; Intensive Care Unit, John Hunter Hospital, Newcastle, New South Wales 2308, Australia., Bracke KR; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent 9000, Belgium., Jarnicki AG; Department of Biochemistry and Pharmacology, University of Melbourne, Victoria 3010, Australia., Donovan C; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, New South Wales 2007, Australia.; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia., Hsu AC; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia., Ieni A; Department of Human Pathology in Adult and Developmental Age 'Gaetano Barresi', Section of Anatomic Pathology, University of Messina, Messina 98100, Italy., Beckett EL; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia., Galvão I; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, New South Wales 2007, Australia., Wijnant S; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent 9000, Belgium., Ricciardolo FL; Rare Lung Disease Unit, Department of Clinical and Biological Sciences, University of Torino, San Luigi Gonzaga University Hospital Orbassano, Torino 10043, Italy., Di Stefano A; Istituti Clinici Scientifici Maugeri, IRCCS, SpA Società Benefit, Divisione di Pneumologia e Laboratorio di Citoimmunopatologia dell'Apparato Cardio Respiratorio, Veruno, Novara 28100, Italy., Haw TJ; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia., Liu G; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, New South Wales 2007, Australia., Ferguson AL; Charles Perkins Centre, University of Sydney, Sydney, New South Wales 2006, Australia.; Centenary Institute and University of Technology Sydney, Sydney, New South Wales 2006, Australia., Palendira U; Charles Perkins Centre, University of Sydney, Sydney, New South Wales 2006, Australia., Wark PA; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia., Conickx G; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent 9000, Belgium.; Ablynx N.V., a Sanofi company, Ghent 9052, Belgium., Mestdagh P; Center for Medical Genetics and Cancer Research Institute Ghent (CRIG), Ghent University, Ghent 9000, Belgium., Brusselle GG; Laboratory for Translational Research in Obstructive Pulmonary Diseases, Department of Respiratory Medicine, Ghent University Hospital, Ghent 9000, Belgium., Caramori G; Pneumologia, Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali (BIOMORF), Università di Messina, Messina 98100, Italy., Foster PS; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia., Horvat JC; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia., Hansbro PM; Centre for Inflammation, Centenary Institute and University of Technology Sydney, Sydney, New South Wales 2007, Australia.; Priority Research Centre for Healthy Lungs, Hunter Medical Research Institute and University of Newcastle, Newcastle, New South Wales 2308, Australia.

Publikováno v: Science translational medicine [Sci Transl Med] 2021 Nov 24; Vol. 13 (621), pp. eaav7223. Date of Electronic Publication: 2021 Nov 24.