Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Riccardo V. D'Elia"'
Publikováno v:
International Journal of Infectious Diseases, Vol 40, Iss C, Pp 1-8 (2015)
Introduction: The role of damage-associated molecular pattern HMGB1 signalling in a murine BALB/c model of severe respiratory melioidosis (Burkholderia pseudomallei infection) was explored in this study. Methods: Time course experiments were performe
Externí odkaz:
https://doaj.org/article/d93ce43b13d14aa9b828b387561da435
Autor:
Andrew E. Scott, Sarah A. Ngugi, Thomas R. Laws, David Corser, Claire L. Lonsdale, Riccardo V. D’Elia, Richard W. Titball, E. Diane Williamson, Timothy P. Atkins, Joann L. Prior
Publikováno v:
Journal of Immunology Research, Vol 2014 (2014)
Melioidosis is a severe infectious disease caused by Burkholderia pseudomallei. It is refractory to antibiotic treatment and there is currently no licensed vaccine. In this report we detail the construction and protective efficacy of a polysaccharide
Externí odkaz:
https://doaj.org/article/4b148131007d4b5cb25b8f4c6c672a8e
Autor:
Jon Cuccui, Rebecca M. Thomas, Madeleine G. Moule, Riccardo V. D'Elia, Thomas R. Laws, Dominic C. Mills, Diane Williamson, Timothy P. Atkins, Joann L. Prior, Brendan W. Wren
Publikováno v:
Open Biology, Vol 3, Iss 5 (2013)
Glycoconjugate-based vaccines have proved to be effective at producing long-lasting protection against numerous pathogens. Here, we describe the application of bacterial protein glycan coupling technology (PGCT) to generate a novel recombinant glycoc
Externí odkaz:
https://doaj.org/article/0f1409bae6b94cb78dcdd182ade53f11
Group 2 Innate Lymphoid Cells Are Detrimental to the Control of Infection withFrancisella tularensis
Autor:
Joshua Dow, Urszula M. Cytlak, Joshua Casulli, Craig P. McEntee, Catherine Smedley, Suzanne H. Hodge, Riccardo V. D’Elia, Matthew R. Hepworth, Mark A. Travis
Publikováno v:
The Journal of Immunology. 210:618-627
Innate lymphoid cells (ILCs) are capable of rapid response to a wide variety of immune challenges, including various respiratory pathogens. Despite this, their role in the immune response against the lethal intracellular bacterium Francisella tularen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1625abd5a79e5323fd712a1c440b197f
https://doi.org/10.4049/jimmunol.2100651
https://doi.org/10.4049/jimmunol.2100651
Autor:
Yvonne Perrie, Craig W. Roberts, Swapnil Khadke, Wendy Butcher, Stuart Woods, Jonathan McGahon, E. Diane Williamson, Riccardo V. D'Elia
Publikováno v:
Journal of Controlled Release. 298:202-212
Burkholderia pseudomallei is a Gram-negative intracellular bacterium which is recalcitrant to antibiotic therapy. There also is currently no licensed vaccine for this potentially fatal pathogen, further highlighting the requirement for better therape
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55670360a52f7fe741680cdf2237f8c6
https://doi.org/10.1016/j.jconrel.2019.02.002
https://doi.org/10.1016/j.jconrel.2019.02.002
Autor:
Wendy Butcher, Lyn M. O'Brien, F. Javier Salguero, E. Diane Williamson, Francesca Modino, Stuart Woods, Ana R. Georgian, Craig W. Roberts, Jane E. Preston, N. Joan Abbott, Riccardo V. D'Elia
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 324
The field of brain drug delivery faces many challenges that hinder development and testing of novel therapies for clinically important central nervous system disorders. Chief among them is how to deliver large biologics across the highly restrictive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0884c9de956f00202bbc5fba44381bd1
https://pubmed.ncbi.nlm.nih.gov/32512014
https://pubmed.ncbi.nlm.nih.gov/32512014
Publikováno v:
International Journal of Experimental Pathology
Summary Organ tissue damage is a key contributor to host morbidity and mortality following infection with microbial agents. Severe immune responses, excessive cellular recruitment and necrosis of cells all play a role in disease pathology. Understand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899e7c5c89e6f5dcb6a480358b7de3b4
https://doi.org/10.1111/iep.12258
https://doi.org/10.1111/iep.12258
Publikováno v:
European Journal of Clinical Microbiology & Infectious Diseases
Burkholderia pseudomallei is a Gram-negative intracellular bacterium that causes the disease melioidosis. The disease can be fatal if left untreated or when antibiotic therapy is delayed and total clearance of the pathogen from the host is often not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863003aacabc19786137b1839801a74e
https://doi.org/10.1007/s10096-017-3038-0
https://doi.org/10.1007/s10096-017-3038-0
Autor:
Satya Viswanathan, Jonathan P. Wong, Riccardo V. D'Elia, Lun Quan Sun, Graeme C. Clark, Ming Wang
Publikováno v:
Future Medicinal Chemistry
Emerging pathogenic viruses such as Ebola and Middle Eastern Respiratory Syndrome coronavirus (MERS-CoV) can cause acute infections through the evasion of the host's antiviral immune responses and by inducing the upregulation of inflammatory cytokine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d2a6604623c9e2498f5447502e44925
https://doi.org/10.4155/fmc-2016-0181
https://doi.org/10.4155/fmc-2016-0181
Inflammation is the body's first line of defense against infection or injury, responding to challenges by activating innate and adaptive responses. Microbes have evolved a diverse range of strategies to avoid triggering inflammatory responses. Howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b06859198786c0b870bd08e3f97e914f
https://doi.org/10.1128/cvi.00636-12
https://doi.org/10.1128/cvi.00636-12
