Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Riccardo Rubbiani"'
Publikováno v:
Parasites & Vectors, Vol 7, Iss 1, Pp 1-7 (2014)
Abstract Background Schistosomiasis is a neglected tropical disease and drug-repurposing is a useful strategy to fill its exhausted drug development pipeline. The ferrocenyl analogue of chloroquine, ferroquine, is an antimalarial in late-stage drug d
Externí odkaz:
https://doaj.org/article/11aa53ecf1b2499a91624af77fef08bc
Autor:
William I. O’Malley, Riccardo Rubbiani, Margaret L. Aulsebrook, Michael R. Grace, Leone Spiccia, Kellie L. Tuck, Gilles Gasser, Bim Graham
Publikováno v:
Molecules, Vol 21, Iss 2, p 194 (2016)
A new bifunctional macrocyclic chelator featuring a conjugatable alkynyl-naphthalimide fluorophore pendant group has been prepared and its Gd(III) complex coupled to a cell-penetrating lipidated azido-Tat peptide derivative using Cu(I)-catalysed “c
Externí odkaz:
https://doaj.org/article/d85661e76ea74089aff3dd7f6ee1caa2
Autor:
Yan Lin, Severin Jeger, Giorgia Renga, Jeannine Hess, Kevin Cariou, Luigina Romani, Marco Moretto, Gilles Gasser, Noemi Tocci, Stefano Ferrari, Marilena Pariano, Andres Kaech, Riccardo Rubbiani, James Ng, Luke Young, John Spencer, Tobias Weil, Anthony L. Moore, Luciano Mastrobuoni
Publikováno v:
RSC Chemical Biology
RSC Chemical Biology, Royal Society of Chemistry, 2021, ⟨10.1039/D1CB00123J⟩
RSC Chemical Biology, 2021, 2 (4), pp.1263-1273. ⟨10.1039/d1cb00123j⟩
RSC Chemical Biology, Royal Society of Chemistry, 2021, 2 (4), pp.1263-1273. ⟨10.1039/d1cb00123j⟩
RSC Chemical Biology, Royal Society of Chemistry, 2021, ⟨10.1039/D1CB00123J⟩
RSC Chemical Biology, 2021, 2 (4), pp.1263-1273. ⟨10.1039/d1cb00123j⟩
RSC Chemical Biology, Royal Society of Chemistry, 2021, 2 (4), pp.1263-1273. ⟨10.1039/d1cb00123j⟩
Fungal infections represent a global problem, notably for immunocompromised patients in hospital, COVID-19 patient wards and care home settings, and the ever-increasing emergence of multidrug resistant fungal strains is a sword of Damocles hanging ov
Autor:
Andres Kaech, John Spencer, James Ng, Luigina Romani, Yan Lin, Stefano Ferrari, Luciano Mastrobuoni, Severin Jeger, Jeannine Hess, Riccardo Rubbiani, Kevin Cariou, Noemi Tocci, Gilles Gasser, Renga Giorgia, Tobias Weil, Anthony L. Moore, Marco Moretto, Luke Young, Monica Borghi
Fungal infections are an alarming global problem, most importantly for immunocompromised patients in a hospital environment. The appearance of multidrug resistance in several fungal species is a strong indication that alternative treatments are requi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08005ba8179546b26bb8d24a74e28b4e
https://doi.org/10.26434/chemrxiv.12672794.v1
https://doi.org/10.26434/chemrxiv.12672794.v1
Autor:
Gilles Gasser, Elisa Colombo, Cristina Mari, Malay Patra, Saonli Roy, Robin Vinck, Riccardo Rubbiani
Publikováno v:
ChemBioChem
ChemBioChem, Wiley-VCH Verlag, 2020, ⟨10.1002/cbic.202000289⟩
ChemBioChem, 2020, ⟨10.1002/cbic.202000289⟩
ChemBioChem, Wiley-VCH Verlag, 2020, ⟨10.1002/cbic.202000289⟩
ChemBioChem, 2020, ⟨10.1002/cbic.202000289⟩
International audience; In the fight against cancer, photodynamic therapy is generating great interest thanks to its ability to selectively kill cancer cells without harming healthy tissues. In this field, ruthenium(II) polypyridyl complexes, and mor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd0b26f6c7545b17563c4ce6cbd45fa3
https://hal.archives-ouvertes.fr/hal-02732917/document
https://hal.archives-ouvertes.fr/hal-02732917/document
Autor:
Anna, Notaro, Angelo, Frei, Riccardo, Rubbiani, Marta, Jakubaszek, Uttara, Basu, Severin, Koch, Cristina, Mari, Mazzarine, Dotou, Olivier, Blacque, Jérémie, Gouyon, Fethi, Bedioui, Nils, Rotthowe, Rainer F, Winter, Bruno, Goud, Stefano, Ferrari, Mickaël, Tharaud, Martina, Řezáčová, Jana, Humajová, Pavel, Tomšík, Gilles, Gasser
Publikováno v:
Journal of medicinal chemistry. 63(10)
Chemotherapy remains one of the dominant treatments to cure cancer. However, due to the many inherent drawbacks, there is a search for new chemotherapeutic drugs. Many classes of compounds have been investigated over the years to discover new targets
Autor:
Nils Rotthowe, Marta Jakubaszek, Riccardo Rubbiani, Fethi Bedioui, Mickaël Tharaud, Severin Koch, Martina Řezáčová, Jana Humajova, Cristina Mari, Bruno Goud, Angelo Frei, Pavel Tomsik, Jérémie Gouyon, Gilles Gasser, Anna Notaro, Olivier Blacque, Rainer F. Winter, Mazzarine Dotou, Stefano Ferrari, Uttara Basu
Publikováno v:
Journal of Medicinal Chemistry
Journal of Medicinal Chemistry, 2020, ⟨10.1021/acs.jmedchem.0c00431⟩
Journal of Medicinal Chemistry, American Chemical Society, 2020, ⟨10.1021/acs.jmedchem.0c00431⟩
Journal of Medicinal Chemistry, 2020, ⟨10.1021/acs.jmedchem.0c00431⟩
Journal of Medicinal Chemistry, American Chemical Society, 2020, ⟨10.1021/acs.jmedchem.0c00431⟩
Chemotherapy remains one of the dominant treatments to cure cancer. However, due to the many inherent drawbacks, there is a surge for new chemotherapeutic drugs. More specifically, the discovery of new drug candidates able to overcome severe side eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03455268a4b45179009dd9a9d679997a
https://hal.science/hal-02551981
https://hal.science/hal-02551981
Autor:
Riccardo Rubbiani, Wenyu Wu, Lukas Schneider, Doris Hinger, Vipin Babu, Anu Naik, Bernhard Spingler, Michele Larocca, Christiane König, Gilles Gasser, Roxane Padrutt, Caroline Maake, Stefano Ferrari
Publikováno v:
Chemical Communications
Chemical Communications, Royal Society of Chemistry, 2020, ⟨10.1039/D0CC05196A⟩
Chemical Communications, Royal Society of Chemistry, 2020, ⟨10.1039/D0CC05196A⟩
We report the synthesis of novel tetraplatinated metalloporphyrin-based photosensitizers (PSs) for photodynamic therapy (PDT), their characterization, cellular uptake and localization, as well as the determination of their in vitro light-induced anti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b54e88f860424e84bf4b9dd3e7c30aa4
https://hal.archives-ouvertes.fr/hal-02973034/document
https://hal.archives-ouvertes.fr/hal-02973034/document
Autor:
Huaiyi Huang, Gilles Gasser, Filipa Mendes, Amparo Alvarez-Valdés, Letícia Quental, António Paulo, Adoración G. Quiroga, Riccardo Rubbiani, Paula D. Raposinho, Carmen Navarro-Ranninger, Hui Chao, Isabel Santos
Publikováno v:
Dalton Transactions. 46:14523-14536
In this article, we report on the development of new metal-based anticancer agents with imaging, chemotherapeutic and photosensitizing properties. Hence, a new heterobimetallic complex (Pt-LQ-Re) was prepared by connecting a non-conventional trans-ch
Publikováno v:
Inorganica Chimica Acta. 454:21-26
The use of Ru complexes in light-mediated treatment of cancer (i.e. Photodynamic Therapy – PDT) has recently become extremely relevant with the entry into clinical trials of the first complex of this class against bladder cancer in the very near fu