Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Riccardo Roberto de Lucia"'
Autor:
Alessandro Vinceti, Emre Karakoc, Clare Pacini, Umberto Perron, Riccardo Roberto De Lucia, Mathew J. Garnett, Francesco Iorio
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
Abstract Background CRISPR-Cas9 genome-wide screens are being increasingly performed, allowing systematic explorations of cancer dependencies at unprecedented accuracy and scale. One of the major computational challenges when analysing data derived f
Externí odkaz:
https://doaj.org/article/f7df6232fdbd4a2691e1047e936b4957
Autor:
Emre Karakoc, Umberto Perron, Riccardo Roberto De Lucia, Clare Pacini, Mathew J. Garnett, Francesco Iorio, Alessandro Vinceti
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-16 (2021)
BMC Genomics
BMC Genomics
Background CRISPR-Cas9 genome-wide screens are being increasingly performed, allowing systematic explorations of cancer dependencies at unprecedented accuracy and scale. One of the major computational challenges when analysing data derived from such
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac8507f5d05470824a97a315f774baf3
https://doaj.org/article/f7df6232fdbd4a2691e1047e936b4957
https://doaj.org/article/f7df6232fdbd4a2691e1047e936b4957
Autor:
Alessandro Vinceti, Riccardo Roberto de Lucia, Paolo Cremaschi, Umberto Perron, Emre Karacok, Luca Mauri, Carlos Fernandez, Krzysztof Henryk Kluczynski, Daniel Stephen Anderson, Francesco Iorio
SummaryA limitation of pooled CRISPR-Cas9 viability screens is the high false-positive rate in detecting essential genes arising from copy number-amplified (CNA) regions of the genome. To solve this issue, we developed CRISPRcleanR: a computational m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8b6dfeb49fa9d1e1e9d0d061bb9df6c2
https://doi.org/10.1101/2022.03.11.483924
https://doi.org/10.1101/2022.03.11.483924
Autor:
Alessandro Vinceti, Riccardo Roberto De Lucia, Paolo Cremaschi, Umberto Perron, Emre Karakoc, Luca Mauri, Carlos Fernandez, Krzysztof Henryk Kluczynski, Daniel Stephen Anderson, Francesco Iorio
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b9b6b3219106a173c8b4d7a24b78770f
https://doi.org/10.2139/ssrn.4081522
https://doi.org/10.2139/ssrn.4081522
Autor:
Alessandro Vinceti, Riccardo Roberto De Lucia, Paolo Cremaschi, Umberto Perron, Emre Karakoc, Luca Mauri, Carlos Fernandez, Krzysztof Henryk Kluczynski, Daniel Stephen Anderson, Francesco Iorio
Publikováno v:
Cell Reports Methods. 3:100373
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5bca8e621d9848afddd7c3c6ccc4180a
https://doi.org/10.1016/j.crmeth.2022.100373
https://doi.org/10.1016/j.crmeth.2022.100373