Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Riccardo Rigo"'
Autor:
Pavlína Víšková, Eva Ištvánková, Jan Ryneš, Šimon Džatko, Tomáš Loja, Martina Lenarčič Živković, Riccardo Rigo, Roberto El-Khoury, Israel Serrano-Chacón, Masad J. Damha, Carlos González, Jean-Louis Mergny, Silvie Foldynová-Trantírková, Lukáš Trantírek
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract I-Motifs (iM) are non-canonical DNA structures potentially forming in the accessible, single-stranded, cytosine-rich genomic regions with regulatory roles. Chromatin, protein interactions, and intracellular properties seem to govern iM forma
Externí odkaz:
https://doaj.org/article/dccb82735cd744549a5a5749aaeca993
Autor:
Riccardo Rigo, Rabie Chelbi, Julie Agopian, Sebastien Letard, Aurélien Griffon, Hussein Ghamlouch, Julien Vernerey, Vasileios Ladopoulos, Edwige Voisset, Paulo De Sepulveda, Geoffrey Guittard, Jacques A. Nunès, Ghislain Bidaut, Berthold Göttgens, Michael Weber, Olivier A. Bernard, Patrice Dubreuil, Erinn Soucie
Publikováno v:
JCI Insight, Vol 7, Iss 7 (2022)
Mutation of the TET2 DNA-hydroxymethylase has been associated with a number of immune pathologies. The disparity in phenotype and clinical presentation among these pathologies leads to questions regarding the role of TET2 mutation in promoting diseas
Externí odkaz:
https://doaj.org/article/4730970c79894bdda7977a2e88bc7e6f
Publikováno v:
Pharmaceuticals, Vol 15, Iss 3, p 373 (2022)
In the past two decades, significant efforts have been put into designing small molecules to target selected genomic sites where DNA conformational rearrangements control gene expression. G-rich sequences at oncogene promoters are considered good poi
Externí odkaz:
https://doaj.org/article/be7b308e7f6145ed85ce118636e2c203
Autor:
Silvia Da Ros, Giulia Nicoletto, Riccardo Rigo, Silvia Ceschi, Eleonora Zorzan, Mauro Dacasto, Mery Giantin, Claudia Sissi
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1, p 329 (2020)
The regulation of conformational arrangements of gene promoters is a physiological mechanism that has been associated with the fine control of gene expression. Indeed, it can drive the time and the location for the selective recruitment of proteins o
Externí odkaz:
https://doaj.org/article/635fe677dcd64618aa409350e23683f0
Autor:
Claudia Sissi, Mery Giantin, Silvia Ceschi, Riccardo Rigo, Giulia Nicoletto, Silvia Da Ros, Eleonora Zorzan, Mauro Dacasto
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 329, p 329 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 1
International Journal of Molecular Sciences
Volume 22
Issue 1
The regulation of conformational arrangements of gene promoters is a physiological mechanism that has been associated with the fine control of gene expression. Indeed, it can drive the time and the location for the selective recruitment of proteins o
Publikováno v:
Nucleic Acids Research
In the promoter of c-KIT proto-oncogene, whose deregulation has been implicated in many cancers, three G-rich regions (kit1, kit* and kit2) are able to fold into G-quadruplexes. While kit1 and kit2 have been studied in depth, little information is av
Autor:
Luca Nardo, Mauro Dacasto, Claudia Adriana Marrano, Riccardo Rigo, Domenico Salerno, Enrico Buglione, Francesco Mantegazza, Claudia Sissi, Valeria Cassina, Guglielmo Vesco
Publikováno v:
Nucleic Acids Research
G-quadruplexes (G4s) are tetrahelical DNA structures stabilized by four guanines paired via Hoogsteen hydrogen bonds into quartets. While their presence within eukaryotic DNA is known to play a key role in regulatory processes, their functional mecha
Autor:
Giulia Nicoletto, Maria Bondani, Claudia Sissi, Francesco Mantegazza, Marco Lamperti, Domenico Salerno, Luca Nardo, Claudia Adriana Marrano, Enrico Buglione, Riccardo Rigo, Guglielmo Vesco, Valeria Cassina
Publikováno v:
Nucleic Acids Research
G-quadruplexes embedded within promoters play a crucial role in regulating the gene expression. KIT is a widely studied oncogene, whose promoter contains three G-quadruplex forming sequences, c-kit1, c-kit2 and c-kit*. For these sequences available s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20d0fefc5802ca40540e8a54b7815d0e
http://hdl.handle.net/11577/3419180
http://hdl.handle.net/11577/3419180
Autor:
Paolo Scrimin, Riccardo Rigo, Fabrizio Mancin, Claudia Sissi, Marco De Vivo, Adam Pecina, Susanna Zamolo, Tamis Darbre, Joanna Czescik, Laura Riccardi
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
Similarly to enzymes, functionalized gold nanoparticles efficiently catalyze chemical reactions, hence the term nanozymes. Herein, we present our results showing how surface‐passivated gold nanoparticles behave as synthetic nanonucleases, able to c
Autor:
Marta Ferraroni, Riccardo Rigo, Carla Bazzicalupi, Paola Gratteri, Francesco Papi, Claudia Sissi, S. Da Ros
Publikováno v:
Journal of Natural Products. 80:3128-3135
The binding properties toward the human telomeric G-quadruplex of the two natural alkaloids coptisine and chelerythrine were studied using spectroscopic techniques, molecular modeling, and X-ray diffraction analysis. The results were compared with re