Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Riccardo Provenzani"'
Autor:
Riccardo Provenzani, Paola San-Martin-Galindo, Ghada Hassan, Ashenafi Legehar, Aleksi Kallio, Henri Xhaard, Adyary Fallarero, Jari Yli-Kauhaluoma
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Biofilms are multicellular communities of microorganisms that generally attach to surfaces in a self-produced matrix. Unlike planktonic cells, biofilms can withstand conventional antibiotics, causing significant challenges in the healthcare
Externí odkaz:
https://doaj.org/article/31c6533710d348fb836b7b06e81689d3
Autor:
Riccardo Provenzani, Ilari Tarvainen, Giulia Brandoli, Antti Lempinen, Sanna Artes, Ainoleena Turku, Maria Helena Jäntti, Virpi Talman, Jari Yli-Kauhaluoma, Raimo K Tuominen, Gustav Boije Af Gennäs
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195668 (2018)
Protein kinase C (PKC) isoforms play a pivotal role in the regulation of numerous cellular functions, making them extensively studied and highly attractive drug targets. Utilizing the crystal structure of the PKCδ C1B domain, we have developed hydro
Externí odkaz:
https://doaj.org/article/011c3ac1fd414b3695e15b73be2e16e1
Autor:
Saara Lautala, Riccardo Provenzani, Ilari Tarvainen, Katia Sirna, S. Tuuli Karhu, Evgeni Grazhdankin, Antti K. Lehtinen, Hanan Sa’d, Artturi Koivuniemi, Henri Xhaard, Raimo K. Tuominen, Virpi Talman, Alex Bunker, Jari Yli-Kauhaluoma
Publikováno v:
Journal of Medicinal Chemistry. 66:4588-4602
Autor:
Riccardo Provenzani, Alex Bunker, Raimo K. Tuominen, Virpi Talman, Jari Yli-Kauhaluoma, Saara Lautala, Waldemar Kulig, Artturi Koivuniemi, Tomasz Róg
Publikováno v:
Journal of Chemical Information and Modeling. 60:5624-5633
Increasing protein kinase C (PKC) activity is of potential therapeutic value. Its activation involves an interaction between the C1 domain and diacylglycerol (DAG) at intracellular membrane surfaces; DAG mimetics hold promise as new drugs. We previou
Autor:
Angela Serra, Michele Fratello, Antonio Federico, Ravi Ojha, Riccardo Provenzani, Ervin Tasnadi, Luca Cattelani, Giusy del Giudice, Pia A S Kinaret, Laura A Saarimäki, Alisa Pavel, Suvi Kuivanen, Vincenzo Cerullo, Olli Vapalahti, Peter Horvath, Antonio Di Lieto, Jari Yli-Kauhaluoma, Giuseppe Balistreri, Dario Greco
Publikováno v:
Briefings in Bioinformatics
The pharmacological arsenal against the COVID-19 pandemic is largely based on generic anti-inflammatory strategies or poorly scalable solutions. Moreover, as the ongoing vaccination campaign is rolling slower than wished, affordable and effective the
Autor:
Jouko Peltonen, Jawad Sarfraz, Sari Tähkä, Tiina Sikanen, Riccardo Provenzani, Susanne K. Wiedmer, Lauri Urvas, Ville Jokinen
Publikováno v:
Analytical and Bioanalytical Chemistry
openaire: EC/H2020/| 311705/EU//CUMTAS We introduce rapid replica molding of ordered, high-aspect-ratio, thiol-ene micropillar arrays for implementation of microfluidic immobilized enzyme reactors (IMERs). By exploiting the abundance of free surface
Autor:
Ashenafi Legehar, Henri Xhaard, Jari Yli-Kauhaluoma, Ghada S. Hassan, Paola San-Martin-Galindo, Adyary Fallarero, Riccardo Provenzani, Aleksi Onni Oskari Kallio
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Scientific Reports
Scientific Reports
Biofilms are multicellular communities of microorganisms that generally attach to surfaces in a self-produced matrix. Unlike planktonic cells, biofilms can withstand conventional antibiotics, causing significant challenges in the healthcare system. C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d96d7b6250d0423c6abe76ff2c928d0
http://hdl.handle.net/10138/330347
http://hdl.handle.net/10138/330347
Autor:
Markku Varjosalo, Cristian Vergallo, Christian Celia, Luisa Di Marzio, Karina Moslova, Felisa Cilurzo, Maria Chiara Cristiano, Massimo Fresta, Hélder A. Santos, Sini Miettinen, Giulia Torrieri, Riccardo Provenzani
Publikováno v:
International Journal of Pharmaceutics. 573:118826
Stanozolol (STZ) is a drug used to treat serious disorders like aplastic anemia and hereditary angioedema. It is also indicated as an adjunct therapy for the treatment of vascular disorders and growth failures. Encouraging results obtained using anim
Autor:
Virpi Talman, Gustav Boije af Gennäs, Jari Yli-Kauhaluoma, Raimo K. Tuominen, Giulia Brandoli, Sanna Artes, Ilari Tarvainen, Ainoleena Turku, Riccardo Provenzani, Maria Jäntti, Antti Lempinen
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 4, p e0195668 (2018)
PLoS ONE, Vol 13, Iss 4, p e0195668 (2018)
Protein kinase C (PKC) isoforms play a pivotal role in the regulation of numerous cellular functions, making them extensively studied and highly attractive drug targets. Utilizing the crystal structure of the PKC delta C1B domain, we have developed h
Autor:
Raimo K. Tuominen, Jari Yli-Kauhaluoma, Gustav Boije af Gennäs, Riccardo Provenzani, Virpi Talman
Publikováno v:
Biochemical Society transactions. 42(6)
Protein kinase C (PKC) is a serine/threonine kinase belonging to the AGC family. PKC isoenzymes are activated by phospholipid-derived second messengers, transmit their signal by phosphorylating specific substrates and play a pivotal role in the regul