Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Riccardo De Giorgi"'
Autor:
Lea Francia, Riccardo De Giorgi, Elvira Lara, Blanca Dolz del Castellar, Chiara Castelletti, Cristina Rodríguez-Prada, Joan Domènech-Abella, Beatriz Olaya, Josep Maria Haro, José Luis Ayuso Mateos
Publikováno v:
Heliyon, Vol 10, Iss 14, Pp e34571- (2024)
Externí odkaz:
https://doaj.org/article/5dc2a4ad805242b4a3890a391c123c12
Autor:
Lea Francia, Riccardo De Giorgi, Elvira Lara, Blanca Dolz del Castellar, Chiara Castelletti, Cristina Rodríguez-Prada, Joan Domènech-Abella, Beatriz Olaya, Josep Maria Haro, José Luis Ayuso Mateos
Publikováno v:
Heliyon, Vol 10, Iss 11, Pp e32594- (2024)
Background: Despite the availability of effective antidepressant strategies, numerous people with depressive disorders remain untreated. The Covid-19 pandemic has affected healthcare services, especially the mental health sector. This study aims to e
Externí odkaz:
https://doaj.org/article/622c65c1604341c3a64f7937bec8c84d
Autor:
Andrea Cipriani, Edoardo Giuseppe Ostinelli, Seena Fazel, Catherine J Harmer, Franco De Crescenzo, Philip J Cowen, Riccardo De Giorgi
Publikováno v:
BMJ Mental Health, Vol 27, Iss 1 (2024)
Background New National Institute for Health and Care Excellence (NICE) guidance endorses the prescription of statins in larger population groups for the prevention of cardiovascular and cerebrovascular morbidity and mortality, especially in people w
Externí odkaz:
https://doaj.org/article/fd148273a60640d9bef028df2e2fd8ac
Autor:
Riccardo De Giorgi, Franco De Crescenzo, Philip J. Cowen, Catherine J. Harmer, Andrea Cipriani
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-11 (2023)
Abstract Background Antidepressants are licensed for use in depressive disorders, but non-response and poor adherence to treatment affect a considerable number of patients. Pre-clinical and clinical evidence suggest that statins can augment the effec
Externí odkaz:
https://doaj.org/article/cc60bcfd950d4124aebf26c8aed665c4
Autor:
Riccardo De Giorgi, Nicola Rizzo Pesci, Gianluca Rosso, Giuseppe Maina, Philip J. Cowen, Catherine J. Harmer
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Statins are commonly prescribed medications widely investigated for their potential actions on the brain and mental health. Pre-clinical and clinical evidence suggests that statins may play a role in the treatment of depressive disorders, bu
Externí odkaz:
https://doaj.org/article/7a53a7a9161c45ccaf1d893c32fab30c
Autor:
Shona Waters, Riccardo De Giorgi, Alice M. G. Quinton, Amy L. Gillespie, Susannah E. Murphy, Philip J. Cowen, Catherine J. Harmer
Publikováno v:
BJPsych Open, Vol 9 (2023)
Background Evidence suggests inflammation may be a key mechanism by which psychosocial stress, including loneliness, predisposes to depression. Observational and clinical studies have suggested simvastatin, with its anti-inflammatory properties, may
Externí odkaz:
https://doaj.org/article/b79a2803bb724bb284cb8eb11088c530
Autor:
Riccardo De Giorgi, Nicola Rizzo Pesci, Alice Quinton, Franco De Crescenzo, Philip J. Cowen, Catherine J. Harmer
Publikováno v:
Frontiers in Psychiatry, Vol 12 (2021)
Background: Depression is a leading cause of disability, burdened by high levels of non-response to conventional antidepressants. Novel therapeutic strategies targeting non-monoaminergic pathways are sorely needed. The widely available and safe stati
Externí odkaz:
https://doaj.org/article/95f6aabb157f4e058ca50ca4c51578ef
Autor:
Riccardo De Giorgi, Franco De Crescenzo, Nicola Rizzo Pesci, Marieke Martens, Wendy Howard, Philip J Cowen, Catherine J Harmer
Publikováno v:
PLoS ONE, Vol 16, Iss 3, p e0249409 (2021)
BackgroundThe burden of depressive disorder is large and new treatment approaches are required. Repurposing widely available drugs such as statins may be a time- and cost-effective solution. Statins have anti-inflammatory and anti-oxidant properties
Externí odkaz:
https://doaj.org/article/9c597de838d448eb8fdb850bf865bc7c
Autor:
Franco De Crescenzo, Marco Ciabattini, Gian Loreto D'Alò, Riccardo De Giorgi, Cinzia Del Giovane, Carolina Cassar, Luigi Janiri, Nicolas Clark, Michael Joshua Ostacher, Andrea Cipriani
Publikováno v:
PLoS Medicine, Vol 15, Iss 12, p e1002715 (2018)
BackgroundClinical guidelines recommend psychosocial interventions for cocaine and/or amphetamine addiction as first-line treatment, but it is still unclear which intervention, if any, should be offered first. We aimed to estimate the comparative eff
Externí odkaz:
https://doaj.org/article/969ce4fc53504de6be218c3de4ac3685
Publikováno v:
Journal of Psychopharmacology (Oxford, England)
Background: Growing evidence from clinical trials and epidemiological studies suggests that statins can have clinically significant antidepressant effects, potentially related to anti-inflammatory action on several neurobiological structures. However