Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Riccardo Dainese"'
Autor:
Gerard Llimos, Vincent Gardeux, Ute Koch, Judith F. Kribelbauer, Antonina Hafner, Daniel Alpern, Joern Pezoldt, Maria Litovchenko, Julie Russeil, Riccardo Dainese, Riccardo Moia, Abdurraouf Mokhtar Mahmoud, Davide Rossi, Gianluca Gaidano, Christoph Plass, Pavlo Lutsik, Clarissa Gerhauser, Sebastian M. Waszak, Alistair Boettiger, Freddy Radtke, Bart Deplancke
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-21 (2022)
Non-coding variants can regulate transcription factor binding and gene expression at variable chromatin modules. Here, the authors show that a germline variant induces transcription factor nucleation through chromatin compaction leading to AXIN2 up-r
Externí odkaz:
https://doaj.org/article/a45f0167b2ac4647bf70d5df2f44a6e7
Autor:
Michael V. Frochaux, Maroun Bou Sleiman, Vincent Gardeux, Riccardo Dainese, Brian Hollis, Maria Litovchenko, Virginie S. Braman, Tommaso Andreani, Dani Osman, Bart Deplancke
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-19 (2020)
Abstract Background Resistance to enteric pathogens is a complex trait at the crossroads of multiple biological processes. We have previously shown in the Drosophila Genetic Reference Panel (DGRP) that resistance to infection is highly heritable, but
Externí odkaz:
https://doaj.org/article/8e53e953bb0541ca9e5d26a86a654e52
Autor:
Wanze Chen, Petra C. Schwalie, Eugenia V. Pankevich, Carine Gubelmann, Sunil K. Raghav, Riccardo Dainese, Marco Cassano, Michael Imbeault, Suk Min Jang, Julie Russeil, Tenagne Delessa, Julien Duc, Didier Trono, Christian Wolfrum, Bart Deplancke
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Although Krüppel-associated box zinc finger proteins (KZFPs) were found to mostly repress transposable elements, recent studies found that KFZPs also play other roles in cells. Here, the authors provide evidence that the KZFP ZFP30 promotes adipogen
Externí odkaz:
https://doaj.org/article/79c0840feab948d880b74c9fb3a62bf1
Autor:
Leila Shokri, Sachi Inukai, Antonina Hafner, Kathryn Weinand, Korneel Hens, Anastasia Vedenko, Stephen S. Gisselbrecht, Riccardo Dainese, Johannes Bischof, Edy Furger, Jean-Daniel Feuz, Konrad Basler, Bart Deplancke, Martha L. Bulyk
Publikováno v:
Cell Reports, Vol 27, Iss 3, Pp 955-970.e7 (2019)
Summary: Combinatorial interactions among transcription factors (TFs) play essential roles in generating gene expression specificity and diversity in metazoans. Using yeast 2-hybrid (Y2H) assays on nearly all sequence-specific Drosophila TFs, we iden
Externí odkaz:
https://doaj.org/article/9e3550215eb148d5a27340a7e617b017
Autor:
Bart Deplancke, Vincent Gardeux, Jia Yuan Jiang, Gerard Llimos, Antonio C. A. Meireles-Filho, Riccardo Dainese, Daniel Alpern
Publikováno v:
Proc Natl Acad Sci U S A
Despite its popularity, chromatin immunoprecipitation followed by sequencing (ChIP-seq) remains a tedious (>2 d), manually intensive, low-sensitivity and low-throughput approach. Here, we combine principles of microengineering, surface chemistry, and
Autor:
Wanze Chen, Orane Guillaume-Gentil, Pernille Yde Rainer, Christoph G. Gäbelein, Wouter Saelens, Vincent Gardeux, Amanda Klaeger, Riccardo Dainese, Magda Zachara, Tomaso Zambelli, Julia A. Vorholt, Bart Deplancke
Publikováno v:
Nature, 608 (7924)
Nature
Nature
Single-cell transcriptomics (scRNA-seq) has greatly advanced our ability to characterize cellular heterogeneity. However, scRNA-seq requires lysing cells, which impedes further molecular or functional analyses on the same cells. Here, we established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6fc08083d617e215e7fa59016f248bf
Publikováno v:
Journal of Theoretical Biology. 473:52-66
During cytokinesis in budding yeast (Saccharomyces cerevisiae) damaged proteins are distributed asymmetrically between the daughter and the mother cell. Retention of damaged proteins is a crucial mechanism ensuring a healthy daughter cell with full r
Publikováno v:
Lab on a Chip. 19:1610-1620
Single-cell RNA-sequencing (scRNA-seq) has revolutionized biomedical research by enabling the in-depth analysis of cell-to-cell heterogeneity of tissues with unprecedented resolution. One of the catalyzing technologies is single cell droplet microflu
Autor:
Matthias P. Lutolf, Joern Pezoldt, Esther Amstad, Manfred Claassen, Riccardo Dainese, Saba Rezakhani, Antonius Chrisnandy, Julie Russeil, Yvan Saeys, Bart Deplancke, Marjan Biočanin, Revant Gupta, Wouter Saelens, Johannes Bues
Single-cell RNA-sequencing (scRNA-seq) has transformed our ability to resolve cellular properties across systems. However, current scRNA-seq platforms are one-size-fits-all approaches that are tailored toward large cell inputs (> 1,000 cells), render
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbe8c4a8cf7ed080c82cf5a5bb9e8506
https://doi.org/10.1101/2020.05.19.103812
https://doi.org/10.1101/2020.05.19.103812
Autor:
Riccardo Dainese, Vincent Gardeux, Bart Deplancke, Antonio C. A. Meireles-Filho, Jia Yuan Jiang, Gerard Llimos, Daniel Alpern
Despite its popularity, chromatin immunoprecipitation followed by sequencing (ChIP-seq) remains a tedious (>2d), manually intensive, low-sensitivity and low-throughput approach. Here, we combine principles of microengineering, surface chemistry and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9900864af2c5ff559362b99d6fb85869