Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Riccardo Chiusaroli"'
Autor:
Riccardo Chiusaroli, Tiziana Piepoli, Tiziano Zanelli, Paola Ballanti, Marco Lanza, Lucio C. Rovati, Gianfranco Caselli
Publikováno v:
International Journal of Rheumatology, Vol 2011 (2011)
Several clinical studies demonstrated that glucosamine sulfate (GS) is effective in controlling osteoarthritis (OA), showing a structure-modifying action. However, little is known about the molecular mechanism(s) by which GS exerts such action and ab
Externí odkaz:
https://doaj.org/article/dc6e8535e88f49f38fb464382503d6c4
Autor:
Riccardo Chiusaroli, William C. Horne, Carl P. Blobel, Victor H. Guaiquil, Roland Baron, Marilena Marzia
Publikováno v:
Biological Chemistry. 392:877-885
The ADAMs (a disintegrin and metalloprotease) contribute to various biological functions including the development of tissues by taking part in cell-cell and cell-matrix interactions. We previously found that ADAM15 is prominently expressed in osteob
Autor:
Cecile Itzsteink, Arata Nakajima, Lynn Neff, Naga Suresh Adapala, Riccardo Chiusaroli, Roland Baron, William C. Horne, Archana Sanjay
Publikováno v:
Journal of Bone and Mineral Research. 24:1162-1172
Cbl proteins are multifunctional adaptor molecules that modulate cellular activity by targeting the ubiquitylating system, endocytic complexes, and other effectors to a wide variety of regulatory proteins, especially activated receptor and nonrecepto
Autor:
Athar H. Chishti, Riccardo Chiusaroli, William C. Horne, Roland Baron, Lynn Neff, Marilena Marzia, Na-Young Kim
Publikováno v:
Journal of Biological Chemistry. 281:9745-9754
Osteoclast motility is thought to depend on rapid podosome assembly and disassembly. Both mu-calpain and m-calpain, which promote the formation and disassembly of focal adhesions, were observed in the podosome belt of osteoclasts. Calpain inhibitors
Autor:
Marie Kveiborg, Roland Baron, William C. Horne, Riccardo Chiusaroli, George Sabatakos, Meilin Wu, William M. Philbrick
Publikováno v:
Molecular and Cellular Biology. 24:2820-2830
Although osteoblasts and adipocytes represent two morphologically and functionally distinct cell types, it has been proposed that they may develop from a common mesenchymal precursor in the bone marrow (36, 40, 43). Indeed, an inverse relationship be
Autor:
Chen Luxenburg, Shira Granot-Attas, Archana Sanjay, Roland Baron, Riccardo Chiusaroli, Zohar Tiran, Alon Harmelin, Ari Elson, Tsuyoshi Miyazaki, Hilla Knobler
Publikováno v:
Molecular Biology of the Cell. 15:234-244
Protein tyrosine phosphorylation is a major regulator of bone metabolism. Tyrosine phosphatases participate in regulating phosphorylation, but roles of specific phosphatases in bone metabolism are largely unknown. We demonstrate that young (
Autor:
Keisuke Horiuchi, Hui Cai, Carl P. Blobel, Klaus T. Preissner, Riccardo Chiusaroli, Roland Baron, Thomas Ludwig, Lawrence G. Lum, Gisela Weskamp, Hans-Peter Hammes, Thomas A. Brodie, Katia Manova
Publikováno v:
Molecular and Cellular Biology. 23:5614-5624
Metalloprotease-disintegrins (ADAMs) are a family of membrane-anchored glycoproteins that are related to snake venom metalloproteases and integrin ligands, termed disintegrins. ADAMs have been implicated in fertilization, myogenesis, neurogenesis, an
Autor:
G. Sabatakos, Min Wu, William C. Horne, Riccardo Chiusaroli, Natalie A. Sims, Marie Kveiborg, Roland Baron
Publikováno v:
Endocrinology. 143:4304-4309
Transgenic mice overexpressing ΔFosB, a naturally occurring splice variant of FosB, develop an osteosclerotic phenotype. The increased bone formation has been shown to be due, at least in part, to autonomous effects of ΔFosB isoforms on cells of th
Autor:
Francesca Romana Patacchioli, Lionel N.J.L. Marlier, R. Lauro, Ottavia Porzio, P. Borboni, Luciano Angelucci, Riccardo Chiusaroli
Publikováno v:
Journal of Molecular Neuroscience. 9:1-12
Combined quantitative polymerase chain reaction (PCR) and cytosolic binding assay techniques are used to measure mineralocorticoid receptor (MR) and glucocorticoid receptor (GR) mRNA, Kd, and Bma x in various rat central nervous system (CNS) regions,
Autor:
Paul Kostenuik, Ernestina Schipani, Richa Khatri, Clare Thomas, Frank Asuncion, Riccardo Chiusaroli, Michael S. Ominsky, Masanobu Ohishi
Publikováno v:
The American journal of pathology. 174(6)
Intracortical porosities and marrow fibrosis are hallmarks of hyperparathyroidism and are present in bones of transgenic mice expressing constitutively active parathyroid hormone/parathyroid hormone-related protein receptors (PPR*Tg). Cortical porosi