Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Riccardo Cameroni"'
Autor:
Gilberto Coppi, Valentina Iannuccelli, Maria Teresa Bernabei, Eliana Grazia Leo, Riccardo Cameroni
Publikováno v:
Journal of Microencapsulation. 19:37-44
Oral administration of peptide and protein drugs requires their protection from the acidic and enzymatic degradation in the gastro-intestinal environment and their targeting to the absorption zone. For this purpose, an alginate microsystem, as a carr
Publikováno v:
International Journal of Pharmaceutics. 100:107-114
Cylindrical matrices were prepared by compression either of polyvinyl alcohol 100000 or mixtures of the excipient and a drug (sodium salicylate or theophylline). To modify the cylindrical shape, a hole was bored in the centre of the flat surface thro
Publikováno v:
Journal of Microencapsulation. 9:29-39
The effect of drug loading level both on dynamic swelling and drug release was evaluated using crosslinked gelatin microspheres. Owing to water penetration the microsphere diameter went first to a maximum value, which was not affected by the payload;
In order to protect protein and peptide drugs against inactivation by different barriers in the gastro-intestinal tract and to improve their absorption, alginate microparticles as a carrier of L-lactate dehydrogenase, were developed by spray-drying t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b4f59211acef04877400174ca58b7d
https://hdl.handle.net/11380/305597
https://hdl.handle.net/11380/305597
Autor:
Maria Teresa Bernabei, Eliana Grazia Leo, Riccardo Cameroni, Gilberto Coppi, Valentina Iannuccelli
Publikováno v:
ResearcherID
The oral administration of peptidic drugs requires their protection from degradation in the gastric environment and the improvement of their absorption in the intestinal tract. For these requirements, a microsystem based on cross-linked alginate as t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9610a368adaa89368329bc168d3439e5
https://hdl.handle.net/11380/306520
https://hdl.handle.net/11380/306520
The drug release from doxorubicin (DXR)-gelatin nanoparticle conjugates was evaluated by means of a dynamic dialysis technique. The study was carried out in absence and in presence of a proteolytic enzyme (trypsin) able to degrade the carrier. In a p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71fa2e7f574222b693ec5dc99e62e791
https://hdl.handle.net/11380/306316
https://hdl.handle.net/11380/306316
A pre-formulation study was directed to optimize the in vitro floating ability of an air compartment multiple-unit system. Each unit was formed by a coated bead composed of a calcium alginate core separated by an air compartment from a calcium algina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5ab41deb93527f37f1f2e573af18fe9
https://hdl.handle.net/11380/307528
https://hdl.handle.net/11380/307528
The possible involvement of the primary amino group of doxorubicin (DXR) in the cross-linking process of gelatin nanoparticles stabilized by glutaraldehyde was investigated. Nanoparticles were characterized with regard to particle size, drug content,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a246760579166aff0a86eae721c3f1c7
https://hdl.handle.net/11380/304232
https://hdl.handle.net/11380/304232
Autor:
Rossana Panini, Maria Angela Vandelli, Riccardo Cameroni, Eliana Grazia Leo, Gianfranco Salvioli
Publikováno v:
ResearcherID
Cyclodextrins improve the water-solubility of drugs and can mask their haemolytic effect in parenteral use. Because the mechanism by which bile acids induce haemolysis is poorly understood, it has been investigated in the presence of 2-hydroxypropyl-
In order to design and evaluate an implantable device of calcium alginate spheres releasing gentamicin sulphate to prevent or treat bone infections, the interaction between the cationic gentamicin and the polyanionic alginate was examined. Such an in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed300cb68db472d8062544488b559fb7
https://hdl.handle.net/11380/303547
https://hdl.handle.net/11380/303547