Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Riccardo Bonsignore"'
Autor:
Holly M Craven, Riccardo Bonsignore, Vasilis Lenis, Nicolo Santi, Daniel Berrar, Martin Swain, Helen Whiteland, Angela Casini, Karl F Hoffmann
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 2, p e0008770 (2021)
Schistosomiasis is a neglected tropical disease that currently affects over 250 million individuals worldwide. In the absence of an immunoprophylactic vaccine and the recognition that mono-chemotherapeutic control of schistosomiasis by praziquantel h
Externí odkaz:
https://doaj.org/article/9e1a5bac354f45a2b843a94e1b7f943f
Autor:
Antonino Lauria, Gabriele La Monica, Alessio Terenzi, Giuseppe Mannino, Riccardo Bonsignore, Alessia Bono, Anna Maria Almerico, Giampaolo Barone, Carla Gentile, Annamaria Martorana
Publikováno v:
Molecules, Vol 26, Iss 14, p 4309 (2021)
Background: G-quadruplex (G4) forming sequences are recurrent in telomeres and promoter regions of several protooncogenes. In normal cells, the transient arrangements of DNA in G-tetrads may regulate replication, transcription, and translation proces
Externí odkaz:
https://doaj.org/article/998bf8f2183a4abd94326f12ef0f8db3
Autor:
Clemens Kaußler, Darren Wragg, Claudia Schmidt, Guillermo Moreno-Alcántar, Christian Jandl, Johannes Stephan, Roland A. Fischer, Stefano Leoni, Angela Casini, Riccardo Bonsignore
Publikováno v:
Inorganic chemistry. 61(50)
With the aim to improve the design of metal complexes as stabilizers of noncanonical DNA secondary structures, namely, G-quadruplexes (G4s), a series of cyclic dinuclear Au(I) N-heterocyclic carbene complexes based on xanthine and benzimidazole ligan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6b5998bada52c78566d1e921e17d3b
https://pubmed.ncbi.nlm.nih.gov/36484812
https://pubmed.ncbi.nlm.nih.gov/36484812
Publikováno v:
Chemical Communications, 58(36), 5526-5529. ROYAL SOC CHEMISTRY
With the idea of exploiting metal-templated reactions to achieve selective modification of cysteines in proteins for antibacterial applications, an organometallic cyclometalated Au(III) compound was explored in a competitive chemoproteomic approach b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b02e20a643448041de9defad4ee9d7ea
https://doi.org/10.26434/chemrxiv-2022-0s010
https://doi.org/10.26434/chemrxiv-2022-0s010
Autor:
Valeria Scalcon, Alessandra Folda, Riccardo Bonsignore, Jana Aupic, Alessandra Magistrato, Angela Casini, Maria Pia Rigobello
Publikováno v:
Free Radical Biology and Medicine. 201:8
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::31c55ee279e52dbc02de68133fc360fd
https://doi.org/10.1016/j.freeradbiomed.2023.03.055
https://doi.org/10.1016/j.freeradbiomed.2023.03.055
Autor:
Brech Aikman, Riccardo Bonsignore, Ben Woods, Daniel Doellerer, Riccardo Scotti, Claudia Schmidt, Alexandra A. Heidecker, Alexander Pöthig, Edward J. Sayers, Arwyn T. Jones, Angela Casini
Publikováno v:
Dalton Transactions, 51(19). ROYAL SOC CHEMISTRY
With the aim of designing new metallosupramolecular architectures for drug delivery, research has focused on porous 3-dimensional (3D)-metallacages able to encapsulate cytotoxic agents protecting them from metabolism while targeting them to cancer si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::142cbbf79c945c41a8ddba1e7ea04fe0
http://www.scopus.com/inward/record.url?scp=85130259059&partnerID=8YFLogxK
http://www.scopus.com/inward/record.url?scp=85130259059&partnerID=8YFLogxK
Publikováno v:
Chemical communications (Cambridge, England). 58(36)
With the idea of exploiting metal templated C-S bond forming reactions to achieve modification of cysteines in bacterial proteins, a cyclometalated Au(III) compound was explored in a competitive chemoproteomic approach in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3c4a625140f770d790cc408576a418e6
https://pubmed.ncbi.nlm.nih.gov/35420608
https://pubmed.ncbi.nlm.nih.gov/35420608
Publikováno v:
Chemmedchem
Abstract: A series of mononuclear coordination or organometallic AuI/AuIII complexes (1–9) have been comparatively studied in vitro for their antileishmanial activity against promastigotes and amastigotes, the clinically relevant parasite form, of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fce198eb9170a6152337ff1515bfece
https://doi.org/10.1002/cmdc.202000536
https://doi.org/10.1002/cmdc.202000536
Autor:
Mathilde Rigoulet, Angela Casini, Giampaolo Barone, Sophie R. Thomas, Didier Bourissou, Riccardo Bonsignore, Alexander Pöthig, Christian Jandl
Publikováno v:
Chemistry-A European Journal
Chemistry-A European Journal, 2021, 27 (57), pp.14322-14334. ⟨10.1002/chem.202102668⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2021, 27 (57), pp.14322-14334. ⟨10.1002/chem.202102668⟩
Chemistry (Weinheim an Der Bergstrasse, Germany)
Chemistry-A European Journal, 2021, 27 (57), pp.14322-14334. ⟨10.1002/chem.202102668⟩
Chemistry-A European Journal, Wiley-VCH Verlag, 2021, 27 (57), pp.14322-14334. ⟨10.1002/chem.202102668⟩
Chemistry (Weinheim an Der Bergstrasse, Germany)
In recent years, the reactivity of gold complexes was shown to extend well beyond π‐activation and to hold promises to achieve selective cross‐couplings in several C−C and C−E (E=heteroatom) bond forming reactions. Here, with the aim of expl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e9c7049353ec1e76ddf65c5e97b7e5
http://hdl.handle.net/10447/522800
http://hdl.handle.net/10447/522800
Autor:
Angela Casini, Dorenda Oosterhuis, Dirk-Jan Scheffers, Riccardo Bonsignore, Peter Olinga, Parichita Chakraborty
Publikováno v:
ChemMedChem, 16(19), 3060-3070. WILEY-V C H VERLAG GMBH
Chemmedchem
Chemmedchem
The rise of antimicrobial resistance has necessitated novel strategies to efficiently combat pathogenic bacteria. Metal‐based compounds have been proven as a possible alternative to classical organic drugs. Here, we have assessed the antibacterial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875fa384dd3a37d60bdd3b01a0b75987
https://research.rug.nl/en/publications/22b06f16-0384-4714-8bef-f33143b8710e
https://research.rug.nl/en/publications/22b06f16-0384-4714-8bef-f33143b8710e