Zobrazeno 1 - 1
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pro vyhledávání: '"Riccardo Bombelli"'
Autor:
Cunlin Wang, Zhiyan Liang, Jacob Sands, Nisha Mohindra, Tommy Fu, Dajun Yang, Gregory P. Kalemkerian, Yifan Zhai, Ming Lu, Jyoti D. Patel, Zhicong He, Jennifer W Carlisle, Riccardo Bombelli, Robert Winkler, Vakessa Hammock, Angel Qin, Yang Xu
Publikováno v:
Journal of Clinical Oncology. 39:TPS8589-TPS8589
TPS8589 Background: Increased expression of BCL-2, BCL-xL, and MCL-1 allows certain tumors to evade apoptosis. Pelcitoclax is a novel, dual BCL-2/BCL-xL inhibitor with strong single-agent antitumor activity against tumor cells addicted to BCL-2, BCL-