Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Riccardo Ferdani"'
Autor:
Sven H. Hausner, David L. Kukis, M. Karen J. Gagnon, Catherine E. Stanecki, Riccardo Ferdani, John F. Marshall, Carolyn J. Anderson, Julie L. Sutcliffe
Publikováno v:
Molecular Imaging, Vol 8 (2009)
Significant upregulation of the integrin α v β 6 has been described as a prognostic indicator in several cancers, making it an attractive target for tumor imaging. This study compares variants of a PEGylated α v β 6 -targeting peptide, bearing ei
Externí odkaz:
https://doaj.org/article/6f6b4575e93d469e99ad93a943a6c830
Autor:
Javad Garousi, Ying Yue, Johan Rajander, Riccardo Ferdani, Cheng-Bin Yim, Vladimir Tolmachev, Anna Perols, Anna Orlova, Amelie Eriksson Karlström, Sebastian Grimm, Carolyn J. Anderson, Olof Solin, Tove J. Grönroos, Merja Haaparanta-Solin
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-10 (2018)
Scientific Reports
Scientific Reports
The use of long-lived positron emitters 64Cu or 61Cu for labelling of Affibody molecules may improve breast cancer patients’ stratification for HER-targeted therapy. Previous animal studies have shown that the use of triaza chelators for 64Cu label
Autor:
Alexander G. White, Carolyn J. Anderson, Yunjun Guo, Zhengxin Cai, Dexing Zeng, Riccardo Ferdani, Jalpa Modi
Publikováno v:
Molecular Pharmaceutics
Epidermal growth-factor receptor (EGFR) is overexpressed in a wide variety of solid tumors and has served as a well-characterized target for cancer imaging and therapy. Cetuximab was the first mAb targeting EGFR approved by the FDA for the treatment
Publikováno v:
Bioconjugate Chemistry. 23:1470-1477
Somatostatin receptors (SSTr) are overexpressed in a wide range of neuroendocrine tumors, making them excellent targets for nuclear imaging and therapy, and radiolabeled somatostatin analogues have been investigated for positron emission tomography i
Autor:
Edward H. Wong, Gary R. Weisman, Katie J. Heroux, Riccardo Ferdani, Thaddeus J. Wadas, Ashley L. Fiamengo, Daniel C. Hill, Carolyn J. Anderson, Yijie Peng, Arnold L. Rheingold, James A. Golen, Antoinette Y. Odendaal
Publikováno v:
Inorganic Chemistry
Ethylene cross-bridged tetraamine macrocycles are useful chelators in coordination, catalytic, medicinal, and radiopharmaceutical chemistry. Springborg and co-workers developed trimethylene cross-bridged analogues, although their pendant-armed deriva
Autor:
Buck E. Rogers, Samuel Achilefu, Kexian Liang, Christopher D. Sherman, Riccardo Ferdani, Kimberly A. Lears, Rebecca Andrews, Alexander Zheleznyak, Carolyn J. Anderson
Publikováno v:
Journal of Nuclear Medicine. 52:470-477
Bombesin is a 14–amino-acid amphibian peptide that binds with high affinity to the gastrin-releasing peptide receptor (GRPR), which is overexpressed on a variety of solid tumors. It has been demonstrated that bombesin analogs can be radiolabeled wi
Autor:
Riccardo Ferdani, Carolyn J. Anderson, Susan L. Deutscher, Senthil R. Kumar, Fabio Gallazzi, Thomas P. Quinn
Publikováno v:
Cancer Biotherapy and Radiopharmaceuticals. 25:693-703
Epidermal growth factor receptor-2 (EGFR-2) has been implicated in the pathogenesis of breast and other carcinomas. In this report, we tested the ability of a bacteriophage selected peptide KCCYSL, radiolabeled with ⁶⁴Cu, to image EGFR-2 expressi
Autor:
Riccardo Ferdani, Simon R. Cherry, Julie L. Sutcliffe, Arutselvan Natarajan, Huguette Albrecht, Sally J. DeNardo, Carolyn J. Anderson, Li Peng, Kit S. Lam, Ruiwu Liu
Publikováno v:
Journal of Nuclear Medicine. 50:625-634
N-[[4-[[[(2-ethylphenyl)amino]carbonyl]amino]phenyl]acetyl]-N(epsilon)-6-[(2E)-1-oxo-3-(3-pyridinyl-2-propenyl)]-l-lysyl-l-2-aminohexanedioyl-(1-amino-1-cyclohexane)carboxamide (LLP2A) is a high-affinity, high-specificity peptidomimetic ligand (inhib
Publikováno v:
PET Clinics. 4:49-67
The positron emitting radionuclide (64)Cu has a radioactive half-life of 12.7 hours. The decay characteristics of (64)Cu allow for PET images that are comparable in quality to those obtained using (18)F. Given the longer radioactive half-life of (64)
Publikováno v:
New Journal of Chemistry. 27:60-67
A membrane anchored heptapeptide, (C18H37)2NHCOCH2OCH2CO–NH–Gly–Gly–Gly–Pro–Gly–Gly–Gly–OCH2Ph, has proved to be a selective chloride anion transporter that functions in phospholipid bilayer membranes. When Pro was replaced by the n