Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ricardo Ungaro"'
Autor:
Evan L. Barrios, Jack R. Leary, Dijoia B. Darden, Jaimar C. Rincon, Micah Willis, Valerie E. Polcz, Gwendolyn S. Gillies, Jennifer A. Munley, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie-Pierre L. Gauthier, Shawn D. Larson, Laurence Morel, Tyler J. Loftus, Alicia M. Mohr, Robert Maile, Michael P. Kladde, Clayton E. Mathews, Maigan A. Brusko, Todd M. Brusko, Lyle L. Moldawer, Rhonda Bacher, Philip A. Efron
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionSepsis engenders distinct host immunologic changes that include the expansion of myeloid-derived suppressor cells (MDSCs). These cells play a physiologic role in tempering acute inflammatory responses but can persist in patients who devel
Externí odkaz:
https://doaj.org/article/c3d9f1e91fd841aa9fdb8d5f4c7a4bf1
Autor:
Tyler J. Loftus, Ricardo Ungaro, Marvin Dirain, Philip A. Efron, Monty B. Mazer, Kenneth E. Remy, Richard S. Hotchkiss, Luer Zhong, Rhonda Bacher, Petr Starostik, Lyle L. Moldawer, Scott C. Brakenridge
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Both severe SARS-CoV-2 infections and bacterial sepsis exhibit an immunological dyscrasia and propensity for secondary infections. The nature of the immunological dyscrasias for these differing etiologies and their time course remain unclear. In this
Externí odkaz:
https://doaj.org/article/2ca930a417e346b6bc04c8f3b7f64748
Autor:
McKenzie K. Hollen, Julie A. Stortz, Dijoia Darden, Marvin L. Dirain, Dina C. Nacionales, Russell B. Hawkins, Michael C. Cox, Maria-Cecilia Lopez, Jaimar C. Rincon, Ricardo Ungaro, Zhongkai Wang, Quran Wu, Babette Brumback, Marie-Pierre L. Gauthier, Michael Kladde, Christiaan Leeuwenburgh, Mark Segal, Azra Bihorac, Scott Brakenridge, Frederick A. Moore, Henry V. Baker, Alicia M. Mohr, Lyle L. Moldawer, Philip A. Efron
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-16 (2019)
Abstract Background Sepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived
Externí odkaz:
https://doaj.org/article/6b9df6c997a446a79a45c0e33340dd88
Autor:
Dijoia B. Darden, Xiaoru Dong, Maigan A. Brusko, Lauren Kelly, Brittany Fenner, Jaimar C. Rincon, Marvin L. Dirain, Ricardo Ungaro, Dina C. Nacionales, Marie Gauthier, Michael Kladde, Todd M. Brusko, Azra Bihorac, Frederick A. Moore, Tyler Loftus, Rhonda Bacher, Lyle L. Moldawer, Alicia M. Mohr, Philip A. Efron
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundWith the successful implementation of the Surviving Sepsis Campaign guidelines, post-sepsis in-hospital mortality to sepsis continues to decrease. Those who acutely survive surgical sepsis will either rapidly recover or develop a chronic cr
Externí odkaz:
https://doaj.org/article/51a30572482c44a2b71957447ab39708
Autor:
Steven L Raymond, Russell B Hawkins, Julie A Stortz, Tyler J Murphy, Ricardo Ungaro, Marvin L Dirain, Dina C Nacionales, McKenzie K Hollen, Jaimar C Rincon, Shawn D Larson, Scott C Brakenridge, Frederick A Moore, Daniel Irimia, Phil A Efron, Lyle L Moldawer
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205327 (2018)
Sepsis is a common and deadly complication among trauma and surgical patients. Neutrophils must mobilize to the site of infection to initiate an immediate immune response. To quantify the velocity of spontaneous migrating blood neutrophils, we utiliz
Externí odkaz:
https://doaj.org/article/1c5f2e78debb4f66a5976e9c00530182
Autor:
Scott C. Brakenridge, Uan-I Chen, Tyler Loftus, Ricardo Ungaro, Marvin Dirain, Austin Kerr, Luer Zhong, Rhonda Bacher, Petr Starostik, Gabriella Ghita, Uros Midic, Dijoia Darden, Brittany Fenner, James Wacker, Philip A. Efron, Oliver Liesenfeld, Timothy E. Sweeney, Lyle L. Moldawer
Publikováno v:
JAMA network open. 5(7)
Rapid and accurate discrimination of sepsis and its potential severity currently require multiple assays with slow processing times that are often inconclusive in discerning sepsis from sterile inflammation.To analyze a whole-blood, multivalent, host
Autor:
Robert T. Mankowski, Dina C. Nacionales, Lyle L. Moldawer, Thomas L. Clanton, Raad Z. Gharaibeh, Scott C. Brakenridge, Dijoia B Darden, Alicia M. Mohr, Philip A. Efron, F. A. Moore, Christiaan Leeuwenburgh, Russell B. Hawkins, Marvin L. Dirain, Camille G Apple, Michael C. Cox, Orlando Laitano, Ricardo Ungaro, Ryan M. Thomas
Publikováno v:
Shock
Background Older adults have worse outcomes after sepsis than young adults. Additionally, alterations of the gut microbiota have been demonstrated to contribute to sepsis-related mortality. We sought to determine if there were alterations in the gut
Autor:
Ricardo Ungaro, Lyle L. Moldawer, Jaimar Rincon, Philip A. Efron, Dina C. Nacionales, Russell B. Hawkins, Shawn D. Larson, McKenzie K. Hollen
Publikováno v:
Shock
Neonatal sepsis leads to significant morbidity and mortality with the highest risk of death occurring in preterm (
Autor:
Quran Wu, Henry V. Baker, Ricardo Ungaro, Maria-Cecilia Lopez, Azra Bihorac, Dina C. Nacionales, Lyle L. Moldawer, Alicia M. Mohr, Scott C. Brakenridge, Michael P. Kladde, Julie A. Stortz, Dijoia B Darden, Christiaan Leeuwenburgh, Marvin L. Dirain, Jaimar Rincon, Zhongkai Wang, Babette Brumback, Frederick A. Moore, Mark S. Segal, Marie-Pierre L. Gauthier, Philip A. Efron, McKenzie K. Hollen, Michael C. Cox, Russell B. Hawkins
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-16 (2019)
Critical Care
Critical Care
BackgroundSepsis is an increasingly significant challenge throughout the world as one of the major causes of patient morbidity and mortality. Central to the host immunologic response to sepsis is the increase in circulating myeloid-derived suppressor
Autor:
Marie Gauthier, Lyle L. Moldawer, Alicia M. Mohr, Xiaoru Dong, Azra Bihorac, Frederick A. Moore, Todd M. Brusko, Rhonda Bacher, Lauren S Kelly, Dina C. Nacionales, Tyler J. Loftus, Philip A. Efron, Ricardo Ungaro, Dijoia B Darden, Michael P. Kladde, Marvin L. Dirain, Jaimar Rincon, Maigan A. Brusko, Brittany P Fenner
Publikováno v:
Frontiers in Immunology
Frontiers in Immunology, Vol 12 (2021)
Frontiers in Immunology, Vol 12 (2021)
BackgroundWith the successful implementation of the Surviving Sepsis Campaign guidelines, post-sepsis in-hospital mortality to sepsis continues to decrease. Those who acutely survive surgical sepsis will either rapidly recover or develop a chronic cr