Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ricardo Murphy"'
Autor:
Larissa Erben, Jacqueline P. Welday, Marie E. Cronin, Ricardo Murphy, Miguel Skirzewski, Detlef Vullhorst, Steven L. Carroll, Andres Buonanno
Publikováno v:
J Neurochem
Neuregulins (NRGs) and their cognate neuronal receptor ERBB4, which is expressed in GABAergic and dopaminergic neurons, regulate numerous behaviors in rodents and have been identified as schizophrenia at-risk genes. ErbB4 transcripts are alternativel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::696695be6eb8109145564535e32cd828
https://doi.org/10.1111/jnc.15612
https://doi.org/10.1111/jnc.15612
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 16; Pages: 9462
A popular approach to spatiotemporally target genes using the loxP/Cre recombination system is stereotaxic microinjection of adeno-associated virus (AAV) expressing Cre recombinase (AAV_Cre) in specific neuronal structures. Here, we report that AAV_C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::221e0c54ff72f0d4e74cb6785bf6d61e
https://doi.org/10.3390/ijms23169462
https://doi.org/10.3390/ijms23169462
Autor:
Marie E. Cronin, Alexxai V. Kravitz, Andres Buonanno, Ricardo Murphy, Miguel Skirzewski, Wambura C. Fobbs
Publikováno v:
eNeuro
Natural genetic variants of Neuregulin1 (NRG1) and its cognate receptor ErbB4 are associated with a risk for schizophrenia. Whereas most studies on NRG1-ErbB4 signaling have focused on GABAergic interneurons, ErbB4 is also expressed by midbrain dopam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779d34b08c27dab21098544ae9777ec3
https://pubmed.ncbi.nlm.nih.gov/32354758
https://pubmed.ncbi.nlm.nih.gov/32354758
Publikováno v:
The Journal of Physiology. 593:1551-1580
Key points Kv7 (KCNQ/M) channels are known to control excitability and generate subthreshold M-resonance in CA1 hippocampal pyramidal cells, but their properties and functions have not previously been compared along the dorsoventral (septotemporal) a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca75e8c82ec1f7209daeddd3930b7582
https://doi.org/10.1113/jphysiol.2014.280826
https://doi.org/10.1113/jphysiol.2014.280826
Autor:
Ricardo Murphy
Publikováno v:
Clinical and experimental pharmacologyphysiology. 45(1)
There is a tendency to automatically use two-sided tests to assess the statistical significance of experimental results. Yet if a theory predicts the direction of an experimental outcome, or if for some practical (eg clinical) reason an outcome in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b2e116fa54ca8374508fdda2ac3a65
https://pubmed.ncbi.nlm.nih.gov/28323356
https://pubmed.ncbi.nlm.nih.gov/28323356
Autor:
Thomas E. DeCoursey, Ricardo Murphy
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Bioenergetics. 1757(8):996-1011
The phagocyte NADPH oxidase produces superoxide anion (O(2)(.-)) by the electrogenic process of moving electrons across the cell membrane. This charge translocation must be compensated to prevent self-inhibition by extreme membrane depolarization. Ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f70507b24cc1d63530b64484c5065e7
Publikováno v:
The Journal of Physiology. 569:419-431
NADPH oxidase generates reactive oxygen species that are essential to innate immunity against microbes. Like most enzymes, it is sensitive to pH, although the relative importance of pH(o) and pH(i) has not been clearly distinguished. We have taken ad
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ae07c82e169a4c7f87ddc232a27d35e7
https://doi.org/10.1113/jphysiol.2005.094748
https://doi.org/10.1113/jphysiol.2005.094748
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 288:L398-L408
Voltage-gated proton channels are expressed highly in rat alveolar epithelial cells. Here we investigated whether these channels contribute to pH regulation. The intracellular pH (pHi) was monitored using BCECF in cultured alveolar epithelial cell mo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12caf72cdb756fe7c57535f76266b0b2
https://doi.org/10.1152/ajplung.00299.2004
https://doi.org/10.1152/ajplung.00299.2004
Autor:
Thomas E. DeCoursey, Richard A. Levis, Valerij S. Sokolov, Ricardo Murphy, Vladimir V. Cherny
Publikováno v:
The Journal of General Physiology
Voltage-gated proton channels were studied under voltage clamp in excised, inside-out patches of human eosinophils, at various pHi with pHo 7.5 or 6.5 pipette solutions. H+ current fluctuations were observed consistently when the membrane was depolar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dca41bfb8f6d8b8e24afcbca13d2cb2c
http://europepmc.org/articles/PMC2217352
http://europepmc.org/articles/PMC2217352
Publikováno v:
Proceedings of the National Academy of Sciences. 97:14692-14696
The molecular mechanism of tolerance to opiate drugs is poorly understood. We have used single-channel patch–clamp recordings to study opiate receptor effects on dissociated neurons from rat amygdala, a limbic region implicated in addiction process
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50cafda4fc46d8a8209971d0ce4990fe
https://doi.org/10.1073/pnas.97.26.14692
https://doi.org/10.1073/pnas.97.26.14692