Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Ricardo M, Richardson"'
Publikováno v:
Cancer Research. 83:7-7
Activator of G-protein Signaling 3 (AGS3/GPSM1) is a receptor independent activator of G-protein signaling that couples to Gα subunits of the heterotrimeric G-protein to mediate cellular functions. It was previously shown that AGS3 modulates prostat
Autor:
Elizabeth J. Rivers, Ricardo M. Richardson, Nija Burnette, Yahui Li, Xiaoxin L Chen, Ariel J. Thomas, Nikia Smith, Timothy O. Adekoya, Tonya S. Lane
Publikováno v:
Carcinogenesis
Prostate cancer (PCa) constitutes a serious health challenge and remains one of the main causes of cancer-related death among men. The more aggressive form of the disease has been attributed to androgen independence, resulting in a lack of response t
Publikováno v:
Cellular Signalling. 54:69-80
Chemokines play crucial roles in combating microbial infection and initiating tissue repair by recruiting neutrophils in a timely and coordinated manner. In humans, no less than seven chemokines (CXCL1, CXCL2, CXCL3, CXCL5, CXCL6, CXCL7, and CXCL8) a
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 31:PO-134
Chemokines and their receptors are important proteins that promote growth of various malignant tumors. In prostate cancer, some members of the CXC chemokine receptor have been shown to enhance angiogenesis, proliferation and metastasis. In this study
Autor:
Timothy O. Adekoya, Nikia Smith, Ricardo M. Richardson, Xiaoxin L Chen, Joe B. Blumer, Temilade Aladeniyi
Publikováno v:
Carcinogenesis
Prostate cancer (PCa) is a leading cause of cancer death among men, with greater prevalence of the disease among the African American population in the USA. Activator of G-protein signaling 3 (AGS3/G-protein signaling modulator 1) was shown to be ove
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aaa4944d54d4f9377ce126f6ee5264a
https://europepmc.org/articles/PMC7346714/
https://europepmc.org/articles/PMC7346714/
Publikováno v:
Chemokine Receptors and AIDS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4784cf8377c64fda187cc8c86233f776
https://doi.org/10.1201/9780429074974-2
https://doi.org/10.1201/9780429074974-2
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 4449, p 4449 (2020)
International Journal of Molecular Sciences, Vol 21, Iss 4449, p 4449 (2020)
The consequences of prostate cancer metastasis remain severe, with huge impact on the mortality and overall quality of life of affected patients. Despite the convoluted interplay and cross talk between various cell types and secreted factors in the m
Autor:
Vandana Singh, Elizabeth J. Rivers, Ricardo M. Richardson, Sandeep K. Raghuwanshi, Nikia Smith
Publikováno v:
The Journal of Immunology. 192:2186-2194
The interleukin-8 (IL-8/CXCL8) receptors, CXCR1 and CXCR2, couple to Gαi to induce leukocyte recruitment and activation at sites of inflammation. We have recently shown that CXCR1 couples predominantly to the G protein-coupled receptor (GPCR) kinase
Autor:
Pavani Gangavarapu, Krishna Mohan Poluri, Lavanya Rajagopalan, Prem Raj B. Joseph, Roberto P. Garofalo, Krishna Rajarathnam, Sandeep K. Raghuwanshi, Ricardo M. Richardson
Publikováno v:
Biophysical Journal. 105(6):1491-1501
Proteins that exist in monomer-dimer equilibrium can be found in all organisms ranging from bacteria to humans; this facilitates fine-tuning of activities from signaling to catalysis. However, studying the structural basis of monomer function that na
Autor:
Somnath Mukhopadhyay, Sandeep K. Raghuwanshi, Elizabeth J. Rivers, Natalie Sutton, Xiaoxin L Chen, TinChung Leung, Nikia Smith, Ariel J. Thomas, Yuhui Hu, Ricardo M. Richardson
Publikováno v:
The Journal of Immunology. 190:5329-5336
G protein–coupled receptor kinases (GRKs) phosphorylate the activated form of G protein–coupled receptors leading to receptor desensitization and downregulation. We have recently shown that the chemokine receptor, CXCR2, couples to GRK6 to regula