Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Ricardo Laguna-Barraza"'
Autor:
Isabel Gómez-Redondo, Eva Pericuesta, Paula Navarrete-Lopez, Priscila Ramos-Ibeas, Benjamín Planells, Noelia Fonseca-Balvís, Aida Vaquero-Rey, Raúl Fernández-González, Ricardo Laguna-Barraza, Keiko Horiuchi, Alfonso Gutiérrez-Adán
Publikováno v:
iScience, Vol 25, Iss 2, Pp 103860- (2022)
Summary: ZRSR2 is a splicing factor involved in recognition of 3′-intron splice sites that is frequently mutated in myeloid malignancies and several tumors; however, the role of mutations of Zrsr2 in other tissues has not been analyzed. To explore
Externí odkaz:
https://doaj.org/article/dbc4d6a69a474e8ba5832f984bbeea28
Autor:
Mª José Izquierdo-Rico, Carla Moros-Nicolás, Míriam Pérez-Crespo, Ricardo Laguna-Barraza, Alfonso Gutiérrez-Adán, Frédéric Veyrunes, José Ballesta, Vincent Laudet, Pascale Chevret, Manuel Avilés
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2021)
Mammalian eggs are surrounded by an extracellular matrix called the zona pellucida (ZP). This envelope participates in processes such as acrosome reaction induction, sperm binding, protection of the oviductal embryo, and may be involved in speciation
Externí odkaz:
https://doaj.org/article/f158673f8e804a8986784e0d7c7ea276
Autor:
Ismael Lamas-Toranzo, Julieta G Hamze, Enrica Bianchi, Beatriz Fernández-Fuertes, Serafín Pérez-Cerezales, Ricardo Laguna-Barraza, Raúl Fernández-González, Pat Lonergan, Alfonso Gutiérrez-Adán, Gavin J Wright, María Jiménez-Movilla, Pablo Bermejo-Álvarez
Publikováno v:
eLife, Vol 9 (2020)
The fusion of gamete membranes during fertilization is an essential process for sexual reproduction. Despite its importance, only three proteins are known to be indispensable for sperm-egg membrane fusion: the sperm proteins IZUMO1 and SPACA6, and th
Externí odkaz:
https://doaj.org/article/0ee4dbc451934916835f7457ae5ab563
Autor:
Keiko Horiuchi, Serafín Perez-Cerezales, Panagiotis Papasaikas, Priscila Ramos-Ibeas, Angela Patricia López-Cardona, Ricardo Laguna-Barraza, Noelia Fonseca Balvís, Eva Pericuesta, Raul Fernández-González, Benjamín Planells, Alberto Viera, Jose Angel Suja, Pablo Juan Ross, Francisco Alén, Laura Orio, Fernando Rodriguez de Fonseca, Belén Pintado, Juan Valcárcel, Alfonso Gutiérrez-Adán
Publikováno v:
Cell Reports, Vol 23, Iss 1, Pp 143-155 (2018)
Summary: The U2AF35-like ZRSR1 has been implicated in the recognition of 3′ splice site during spliceosome assembly, but ZRSR1 knockout mice do not show abnormal phenotypes. To analyze ZRSR1 function and its precise role in RNA splicing, we generat
Externí odkaz:
https://doaj.org/article/d212e33fab784884b791d952a00bf831
Autor:
Eva Pericuesta, Ricardo Laguna-Barraza, Priscila Ramos-Ibeas, Julia L. Gutierrez-Arroyo, Juan A. Navarro, Katia Vera, Carlos Sanjuan, Elena Baixeras, Fernando Rodríguez de Fonseca, Alfonso Gutierrez-Adan
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 17, p 6049 (2020)
Polycystic ovarian syndrome (PCOS) is the main cause of female infertility. It is a multifactorial disorder with varying clinical manifestations including metabolic/endocrine abnormalities, hyperandrogenism, and ovarian cysts, among other conditions.
Externí odkaz:
https://doaj.org/article/2fef0ea19ff04be1bd2831b88078fd11
Autor:
Isabel Gómez-Redondo, Priscila Ramos-Ibeas, Eva Pericuesta, Raúl Fernández-González, Ricardo Laguna-Barraza, Alfonso Gutiérrez-Adán
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 11, p 4115 (2020)
Minor splicing plays an important role in vertebrate development. Zrsr1 and Zrsr2 paralog genes have essential roles in alternative splicing, mainly participating in the recognition of minor (U12) introns. To further explore their roles during early
Externí odkaz:
https://doaj.org/article/83a1242400b74490be361edd7c45d0c9
Autor:
Priscila Ramos-Ibeas, Alexandra Calle, Raúl Fernández-González, Ricardo Laguna-Barraza, Eva Pericuesta, Antonia Calero, Miguel Ángel Ramírez, Alfonso Gutiérrez-Adán
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e95625 (2014)
Intracytoplasmic sperm injection (ICSI) in mice using DNA-fragmented sperm (DFS) has been linked to an increased risk of genetic and epigenetic abnormalities both in embryos and offspring. This study examines: whether embryonic stem cells (ESCs) deri
Externí odkaz:
https://doaj.org/article/fb610a8c45d84d43aa3b3d678d5c20ac
Autor:
Jon Romero-Aguirregomezcorta, Alfonso Gutiérrez-Adán, Sean Fair, Miriama Štiavnická, Ricardo Laguna-Barraza, Jennifer Cloherty, Andreas M. Grabrucker, Raúl Fernández-González, David Newport, F. Ward, Denis McAuliffe, Peter B Larsen
Publikováno v:
Reproduction. 161:343-352
10 Pág. Departamento de Reproducción animal
The objective of this work was to elucidate whether a sperm selection method that combines rheotaxis and microfluidics can improve the selection of spermatozoa over density gradient and swim-up. For
The objective of this work was to elucidate whether a sperm selection method that combines rheotaxis and microfluidics can improve the selection of spermatozoa over density gradient and swim-up. For
Autor:
Irene Peral‐Sanchez, Sonia Heras, Priscila Ramos-Ibeas, Eva Pericuesta, Ricardo Laguna-Barraza, Alfonso Gutiérrez-Adán, Serafín Pérez-Cerezales
Publikováno v:
Molecular Reproduction and Development. 86:1033-1043
Although telomere length (TL) shortens with age in most tissues, an age-related increase in length has been described in sperm through a mechanism that is not yet fully understood. Changes in TL with age in the same individual have not been explored.
Autor:
Priscila Ramos-Ibeas, Raúl Fernández-González, Benjamín Planells, Serafín Pérez-Cerezales, Ricardo Laguna-Barraza, Sonia Heras, Alfonso Gutiérrez-Adán, Eva Pericuesta, Isabel Gómez-Redondo
Publikováno v:
Molecular Reproduction and Development. 86:1292-1306
Assisted reproductive technology (ART) has led to the birth of millions of babies. In cattle, thousands of embryos are produced annually. However, since the introduction and widespread use of ART, negative effects on embryos and offspring are startin