Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ricardo Kusuda"'
Autor:
Alexandre G. Maganin, Guilherme R. Souza, Miriam D. Fonseca, Alexandre H. Lopes, Rafaela M. Guimarães, André Dagostin, Nerry T. Cecilio, Atlante S. Mendes, William A. Gonçalves, Conceição E.A. Silva, Francisco Isaac Fernandes Gomes, Lucas M. Mauriz Marques, Rangel L. Silva, Letícia M. Arruda, Denis A. Santana, Henrique Lemos, Lei Huang, Marcela Davoli-Ferreira, Danielle Santana-Coelho, Morena B. Sant’Anna, Ricardo Kusuda, Jhimmy Talbot, Gabriela Pacholczyk, Gabriela A. Buqui, Norberto P. Lopes, Jose C. Alves-Filho, Ricardo M. Leão, Jason C. O’Connor, Fernando Q. Cunha, Andrew Mellor, Thiago M. Cunha
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Neuropathic pain is one of the most important clinical consequences of injury to the somatosensory system. Nevertheless, the critical pathophysiological mechanisms involved in neuropathic pain development are poorly understood. In this study, we foun
Externí odkaz:
https://doaj.org/article/c98ec044e03d4d9d88b85df1bc7f3f13
Autor:
Miriam M. Fonseca, Marcela Davoli-Ferreira, Flávia Santa-Cecília, Rafaela M. Guimarães, Francisco F. B. Oliveira, Ricardo Kusuda, David W. Ferreira, José C. Alves-Filho, Fernando Q. Cunha, Thiago M. Cunha
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Neuroimmune–glia interactions have been implicated in the development of neuropathic pain. Interleukin-27 (IL-27) is a cytokine that presents regulatory activity in inflammatory conditions of the central nervous system. Thus, we hypothesized that I
Externí odkaz:
https://doaj.org/article/9d29671462ae4393ba0ae6f5d8f3cd14
Autor:
Yelena Nersesyan, Lusine Demirkhanyan, Deny Cabezas-Bratesco, Victoria Oakes, Ricardo Kusuda, Tyler Dawson, Xiaohui Sun, Chike Cao, Alejandro Martin Cohen, Bharath Chelluboina, Krishna Kumar Veeravalli, Katharina Zimmermann, Carmen Domene, Sebastian Brauchi, Eleonora Zakharian
Publikováno v:
Cell Reports, Vol 21, Iss 6, Pp 1681-1691 (2017)
Summary: Oxytocin is a hormone with various actions. Oxytocin-containing parvocellular neurons project to the brainstem and spinal cord. Oxytocin release from these neurons suppresses nociception of inflammatory pain, the molecular mechanism of which
Externí odkaz:
https://doaj.org/article/f06f98f15c754674b6ca9e4e8cc7a1b0
Autor:
Alexandre G. Maganin, Guilherme R. Souza, Miriam D. Fonseca, Alexandre H. Lopes, Rafaela M. Guimarães, André Dagostin, Nerry T. Cecilio, Atlante S. Mendes, William A. Gonçalves, Conceição E.A. Silva, Francisco Isaac Fernandes Gomes, Lucas M. Mauriz Marques, Rangel L. Silva, Letícia M. Arruda, Denis A. Santana, Henrique Lemos, Lei Huang, Marcela Davoli-Ferreira, Danielle Santana-Coelho, Morena B. Sant’Anna, Ricardo Kusuda, Jhimmy Talbot, Gabriela Pacholczyk, Gabriela A. Buqui, Norberto P. Lopes, Jose C. Alves-Filho, Ricardo M. Leão, Jason C. O’Connor, Fernando Q. Cunha, Andrew Mellor, Thiago M. Cunha
Publikováno v:
The Journal of clinical investigation. 132(23)
Neuropathic pain is one of the most important clinical consequences of injury to the somatosensory system. Nevertheless, the critical pathophysiological mechanisms involved in neuropathic pain development are poorly understood. In this study, we foun
Autor:
Glauce Crivelaro do Nascimento, Christie Ramos Andrade Leite-Panissi, Guilherme de Araújo Lucas, Andrea Carvalho, Sonia Zanon, Flávia C Turcato, Clarissa M.D. Mota, Ricardo Kusuda, Cayo Almeida
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Objective: Animal models of chronic pain have demonstrated that glial cells are promising target for development of analgesic drugs. However, preclinical studies on glial response under chronic pain conditions vary depending on the cellular markers,
Autor:
Guilherme R. Souza, Fernando Q. Cunha, Miriam D. Fonseca, Alexandre H. Lopes, Morena Brazil Sant'Anna, Rangel L. Silva, Gabriela A. Buqui, Jhimmy Talbot, Jason C. O’Connor, Thiago M. Cunha, Rafaela M. Guimarães, Dênis Augusto Reis Santana, Alexandre Gomes de Macedo Maganin, Norberto P. Lopes, Ricardo M. Leão, Atlante S. Mendes, Nerry T. Cecilio, Andre Dagostin, Gabriela Pacholczyk, Letícia Magalhães Arruda, Danielle S. Coelho, Marcela Davoli-Ferreira, Henrique Lemos, Lei Huang, Ricardo Kusuda, José C. Alves-Filho, Lucas Miranda Marques, Andrew L. Mellor, Francisco Isaac Fernandes Gomes
Neuropathic pain is triggered by injury to the somatosensory system, and is one of the most important types of chronic pain. Nevertheless, critical pathophysiological mechanisms that maintain neuropathic pain are poorly understood. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::278a962a7ad05317c4de2966b1899e9d
https://doi.org/10.1101/2021.01.25.428142
https://doi.org/10.1101/2021.01.25.428142
Autor:
Ricardo Kusuda, Eleonora U Carreira, Luis Ulloa, Alexandre Kanashiro, Thiago M. Cunha, Fernando Q. Cunha
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
New findings on neural regulation of immunity are allowing the design of novel pharmacological strategies to control inflammation and nociception. Herein, we report that choline, a 7-nicotinic acetylcholine receptor (α7nAChRs) agonist, prevents carr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5245738251759f441bca0390bd96dd9
Autor:
Andreza Urba de Quadros, Thiago M. Cunha, Miriam M. Fonseca, Fernando Q. Cunha, José C. Alves-Filho, Ricardo Kusuda, Marcela Davoli-Ferreira, Rafaela M. Guimarães, Francisco Isaac Fernandes Gomes, Maria C Cavallini, Kalil Alves de Lima
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
The inflammatory/immune response at the site of peripheral nerve injury participates in the pathophysiology of neuropathic pain. Nevertheless, little is known about the local regulatory mechanisms underlying peripheral nerve injury that counteracts t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941859a6e32d1699fddaf19e9e1c1085
Autor:
Fernando Q. Cunha, Denise Morais da Fonseca, Raphael Gomes Ferreira, Guilherme Cesar Martelossi Cebinelli, Gustavo B. Menezes, André S. Pupo, Ricardo Kusuda, Carlos Hiroji Hiroki, Gabriel Shimizu Bassi, José Carlos Alves-Fiho, Luis Ulloa, Alexandre Kanashiro, Alexander Birbrair, Thiago M. Cunha, André G. Oliveira, Katiussia Pinho da Silva, Mirian D. Fonseca, Carlos W. S. Wanderley
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Universidade de São Paulo (USP)
instacron:USP
Neutrophils are peripheral immune cells that represent the first recruited innate immune defense against infections and tissue injury. However, these cells can also induce overzealous responses and cause tissue damage. Although the role of neutrophil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4affb94f29e52a2c57a34f08a2597216
https://europepmc.org/articles/PMC7023896/
https://europepmc.org/articles/PMC7023896/
Autor:
Luis Eduardo Alves Damasceno, Rafaela M. Guimarães, Gustavo B. Menezes, José C. Alves-Filho, Marcela Davoli-Ferreira, Ricardo Kusuda, Thiago M. Cunha, Flávia V. Santa-Cecília, Miriam M. Fonseca, Fernando Q. Cunha
Publikováno v:
Journal of leukocyte biologyREFERENCES. 106(3)
The development of neuropathic pain after peripheral nerve injury involves neuroimmune–glial interactions in the spinal cord. However, whether the development of neuropathic pain depends on the infiltration of peripheral immune cells, such as monoc