Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ricardo J. Gonzalez-Rothi"'
Autor:
Ricardo J. Gonzalez-Rothi, Yannick Stephan, Antonio Terracciano, Angelina R. Sutin, Martina Luchetti
Publikováno v:
The journals of gerontology. Series B, Psychological sciences and social sciences. 72(6)
Objectives Lung disease is a leading cause of disability and death among older adults. We examine whether personality traits are associated with lung function and shortness of breath (dyspnea) in a national cohort with and without chronic obstructive
Publikováno v:
MedEdPORTAL, Vol 11 (2015)
Introduction Clinical concepts may be difficult to integrate in the preclinical years but are necessary for the development of clinical reasoning skills. The integration of basic sciences with clinical sciences throughout the 4 years of undergraduate
Autor:
Ricardo J. Gonzalez-Rothi, Almut G. Winterstein, Richard Segal, Thomas E Johns, Randy C. Hatton
Publikováno v:
ResearcherID
The ability of a hospital's adverse drug reaction (ADR) database to identify common and repeated patterns of preventable adverse drug events (ADEs) was analyzed. ADR reports collected from 1994 through 2000 were extracted from a teaching hospital's A
Autor:
Edward V. Staab, Willie F. Williams, Ricardo J. Gonzalez-Rothi, Russell Gibson, Patricia J. Mergo, Thomas Helmberger, Pablo R. Ros
Publikováno v:
American Journal of Roentgenology. 170:1355-1360
The purpose of this investigation was to quantitatively assess abnormally low attenuation of the lung by use of three-dimensional volumetric reconstructions from routine helical CT and to assess their correlation with pulmonary function tests.Helical
Publikováno v:
Pharmaceutical Research. 15:461-465
Purpose. To demonstrate the importance of dose and drug release rate for pulmonary targeting of inhaled glucocorticoids using an animal model of intrapulmonary drug deposition.
Publikováno v:
The Journal of Clinical Pharmacology. 37:881-892
Glucocorticoids are predominantly prescribed in asthma therapy as aerosols to achieve high pulmonary effects with reduced systemic spill-over and pronounced pulmonary selectivity. A variety of pharmacokinetic parameters are potentially important for
Autor:
Sandra Suarez, Anatoly Lukyanov, Hans Schreier, Teresa Dalla Costa, Guenther Hochhaus, Hartmut Derendorf, Ricardo J. Gonzalez-Rothi
Publikováno v:
Pharmaceutical Research. 13:1699-1703
Purpose. To explore the use of triamcinolone acetonide phosphate liposomes as a pulmonary targeted drug delivery system. Methods. Triamcinolone acetonide phosphate liposomes composed of 1,2-distearoyl phosphatidylcholine and 1,2-distearoyl phosphatid
Publikováno v:
Clinical Immunotherapeutics. 4:331-337
Microencapsulation of a number of drugs in microscopic phospholipid vesicles (liposomes) for site-targeted delivery of compounds is a novel area of drug delivery. More novel is the application of this concept for aerosol delivery of drugs to the lung
Autor:
Ricardo J. Gonzalez-Rothi, Günther Hochhaus, Hartmut Derendorf, T. Dalla Costa, A. Lukyanov, H. Schreier
Publikováno v:
Pharmaceutical Research. 12:134-137
Triamcinolone acetonide (TA, 22 µg) was given to rats by intravenous (IV) injection or intratracheal (IT) instillation. Free glucocorticoid receptors were monitored over time in liver and lung using an ex-vivo receptor binding technique. After IV ad