Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Ricardo J Carreira"'
Autor:
Jane Harper, Katherine J Adams, Giovanna Bossi, Debbie E Wright, Andrea R Stacey, Nicole Bedke, Ruth Martinez-Hague, Dan Blat, Laure Humbert, Hazel Buchanan, Gabrielle S Le Provost, Zoe Donnellan, Ricardo J Carreira, Samantha J Paston, Luise U Weigand, Martina Canestraro, Joseph P Sanderson, Sophie Botta Gordon-Smith, Kate L Lowe, Karolina A Rygiel, Alex S Powlesland, Annelise Vuidepot, Namir J Hassan, Brian J Cameron, Bent K Jakobsen, Joseph Dukes
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0205491 (2018)
Robust preclinical testing is essential to predict clinical safety and efficacy and provide data to determine safe dose for first-in-man studies. There are a growing number of examples where the preclinical development of drugs failed to adequately p
Externí odkaz:
https://doaj.org/article/c3d7165394b5442098ed39f7073a5fbd
Autor:
Laura Gonzalez-Calero, Ricardo J. Carreira, René J. M. van Zeijl, Fernando Vivanco, Luis Rodríguez Padial, Gloria Alvarez-Llamas, Luis F. Lopez-Almodovar, Maria G. Barderas, Benjamin Balluff, Liam A. McDonnell, Fernando de la Cuesta, Marta Martin-Lorenzo, Aroa S. Maroto
Publikováno v:
Data in Brief, Vol 4, Iss C, Pp 328-331 (2015)
Data in Brief
Data in Brief
Subclinical atherosclerosis cannot be predicted and novel therapeutic targets are needed. The molecular anatomy of healthy and atherosclerotic tissue is pursued to identify ongoing molecular changes in atherosclerosis development. Mass Spectrometry I
Autor:
Gloria Alvarez-Llamas, Fernando Vivanco, Ricardo J. Carreira, Luis F. Lopez-Almodovar, Liam A. McDonnell, Fernando de la Cuesta, Luis Rodríguez Padial, Marta Martin-Lorenzo, Maria G. Barderas, Benjamin Balluff, René J. M. van Zeijl, Aroa S. Maroto, Laura Gonzalez-Calero
Publikováno v:
Journal of Proteomics, 126, 245-251
The molecular anatomy of healthy and atherosclerotic tissue is pursued here to identify ongoing molecular changes in atherosclerosis development. Subclinical atherosclerosis cannot be predicted and novel therapeutic targets are needed. Mass spectrome
Autor:
Ricardo J. Carreira, Bent K. Jakobsen, Michael J. Cundell, David Lowne, Geert P.M. Mommen, Floriana Capuano, Alex Powlesland, Jacob Hurst
Publikováno v:
Cancer Immunology Research. 7:B086-B086
Purpose of Study: In this study we demonstrate accurate prediction of the impact of somatic mutations on the HLA presentation landscape achieved by interrogating a large scale database of 1.4 million unique HLA peptide sequences that have been direct
Autor:
Ricardo J. Carreira, Carlos Silva López, Javier Fernández-Lodeiro, José Luis Capelo, Cristina Núñez, Carlos Lodeiro, Hugo M. Santos, Juan C. Mejuto
Publikováno v:
Tetrahedron. 67:326-333
A new versatile emissive molecular probe (3) derived from 1,5-bis(2-aminophenoxy)-3-oxopenthane bearing two units of 6-nitro-4-oxo-4H-chromene- has been prepared by a Schiff-base condensation method using conventional and green, ultrasound-aided, met
Autor:
Paula Cabrita, Luisa Brito, Regina Freitas, Catarina Fonseca, José Luis Capelo, Ricardo B. Ferreira, Ricardo J. Carreira, Maria João Trigo
Publikováno v:
Talanta. 83:457-463
Four strains of Listeria monocytogenes with different levels of virulence were studied. Two strains were consistently evaluated as virulent (strain 3077) and of low virulence (strain 3993), whereas the other two strains (3006 and 3049) originated con
Publikováno v:
Rapid Communications in Mass Spectrometry. 25:75-87
Herein we report results regarding the optimization and comparison between different ultrasonic-based procedures for protein quantitation by the direct 18O-labeling approach. The labeling procedure was evaluated using different proteins, different ul
Autor:
Ricardo J. Carreira, José Luis Capelo, J. Simal-Gandara, Hugo M. Santos, Carlos Lodeiro, Luz Fernandes
Publikováno v:
Talanta. 80:1476-1486
Nowadays isotopic (18)O-labeling of peptides has recalled the attention of researchers due to its simplicity of application and high versatility for proteomics studies. Protein quantification, differential peptide mass mapping, studies regarding prot
Publikováno v:
PROTEOMICS. 9:4974-4977
We report in this work on the robustness of ultrasonic energy as a tool to speed the isotopic labeling of proteins using the (18)O-decoupling procedure. The first part of the decoupling procedure, comprising protein denaturation, reduction, alkylatio
Publikováno v:
Talanta. 76:400-406
Preliminary results regarding fast isotopic labeling of proteins with (18)O in conjunction with matrix assisted laser desorption ionization time of flight mass spectrometry technique are presented. Similar (16)O/(18)O isotopic labeling ratios were fo