Výsledky vyhledávání - "Ricardo Imbroisi Filho"

Akademický článek

Western diet leads to aging-related tumorigenesis via activation of the inflammatory, UPR, and EMT pathways

Autor: Ricardo Imbroisi Filho, Alan C. Ochioni, Amanda M. Esteves, João G. B. Leandro, Thainá M. Demaria, Mauro Sola-Penna, Patricia Zancan

Publikováno v: Cell Death and Disease, Vol 12, Iss 7, Pp 1-9 (2021)

Abstract Among the principal causative factors for the development of complications related to aging is a diet rich in fats and sugars, also known as the Western diet. This diet advocates numerous changes that might increase the susceptibility to ini

Externí odkaz: https://doaj.org/article/daa4ce0cf50246c6a12043ae50834bce

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Citrate enrichment in a Western diet reduces weight gain via browning of adipose tissues without resolving diet-induced insulin resistance in mice

Autor: Jessica Ristow Branco, Amanda Moreira Esteves, Ricardo Imbroisi Filho, Thainá M. Demaria, Patricia C. Lisboa, Bruna Pereira Lopes, Egberto G. Moura, Patricia Zancan, Mauro Sola-Penna

Publikováno v: Food & Function. 13:10947-10955

Citrate, a major component of processed foods, reduces weight gain without resolving insulin resistance.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b54cff6d4b70c9a29bb3bc772e845d65
https://doi.org/10.1039/d2fo02011d

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Western diet leads to aging-related tumorigenesis via activation of the inflammatory, UPR, and EMT pathways

Autor: Alan C. Ochioni, João G. B. Leandro, Ricardo Imbroisi Filho, Thainá M. Demaria, Patricia Zancan, Mauro Sola-Penna, Amanda M. Esteves

Publikováno v: Cell Death & Disease
Cell Death and Disease, Vol 12, Iss 7, Pp 1-9 (2021)

Among the principal causative factors for the development of complications related to aging is a diet rich in fats and sugars, also known as the Western diet. This diet advocates numerous changes that might increase the susceptibility to initiate can

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a16fbc2f8bdb4d24dd0ac659ef79ad6
http://europepmc.org/articles/PMC8222293

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A Novel Triazole Derivative Drug Presenting In Vitro and In Vivo Anticancer Properties

Autor: Dora C. S. Costa, João G. B. Leandro, Ricardo Imbroisi Filho, Vitor F. Ferreira, Mauro Sola-Penna, Thainá M. Demaria, Daniel T. G. Gonzaga, Patricia Zancan, Fernando de C. da Silva

Publikováno v: Current Topics in Medicinal Chemistry. 18:1483-1493

Background: Cancer is a major cause of death worldwide, despite many different drugs available to treat the disease. This high mortality rate is largely due to the complexity of the disease, which results from several genetic and epigenetic changes.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b085db7b57331063dc16bb9e1cab7e89
https://doi.org/10.2174/1568026618666180917100640

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Clotrimazole presents anticancer properties against a mouse melanoma model acting as a PI3K inhibitor and inducing repolarization of tumor-associated macrophages

Autor: Thainá M. Demaria, Patrícia T. Bozza, Patricia Zancan, Mauro Sola-Penna, Alan C. Ochioni, Ricardo Imbroisi Filho, José Xavier do Nascimento Júnior, Amanda M. Esteves, Filipe S. Pereira-Dutra, João G. B. Leandro

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease. 1867:166263

The immune system is a key component of tumorigenesis, with the latter promoting the development of cancer, its progression and metastasis. In fact, abundant infiltration of tumor-associated macrophages (TAM), which are M2-like macrophages, has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12794ca723ac753f98a2a373a91aa866
https://doi.org/10.1016/j.bbadis.2021.166263

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Design, Synthesis and Biological Evaluation of 1H-1,2,3-Triazole-Linked-1H-Dibenzo[b,h]xanthenes as Inductors of ROS-Mediated Apoptosis in the Breast Cancer Cell Line MCF-7

Autor: Zeinab Ghasemishahrestani, Roberta K. F. Marra, Bárbara V F E Sá, Vitor F. Ferreira, Carolina S. Bortolot, Marcelo I. P. Reis, Fernando de C. da Silva, Patricia Zancan, Ricardo Imbroisi Filho, Luana da S. M. Forezi, Mauro Sola-Penna

Publikováno v: Medicinal chemistry (Shariqah (United Arab Emirates)). 15(2)

Background:Low molecular weight 1,2,3-triazoles and naphthoquinones are endowed with various types of biological activity, such as against cancer, HIV and bacteria. However, in some cases, the conjugation of these two nuclei considerably increases th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65746822800c747e5efc46c9395e22d
https://pubmed.ncbi.nlm.nih.gov/29792156

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