Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ricardo Guerrero-Ferreira"'
Autor:
Lukas Frey, Dhiman Ghosh, Bilal M Qureshi, David Rhyner, Ricardo Guerrero-Ferreira, Aditya Pokharna, Witek Kwiatkowski, Tetiana Serdiuk, Paola Picotti, Roland Riek, Jason Greenwald
Publikováno v:
eLife, Vol 12 (2024)
The aggregation of the protein α-synuclein is closely associated with several neurodegenerative disorders and as such the structures of the amyloid fibril aggregates have high scientific and medical significance. However, there are dozens of unique
Externí odkaz:
https://doaj.org/article/b3148a9d0d8343938297881e5df6743e
Autor:
Ricardo Guerrero-Ferreira, Nicholas MI Taylor, Ana-Andreea Arteni, Pratibha Kumari, Daniel Mona, Philippe Ringler, Markus Britschgi, Matthias E Lauer, Ali Makky, Joeri Verasdonck, Roland Riek, Ronald Melki, Beat H Meier, Anja Böckmann, Luc Bousset, Henning Stahlberg
Publikováno v:
eLife, Vol 8 (2019)
Intracellular inclusions rich in alpha-synuclein are a hallmark of several neuropathological diseases including Parkinson’s disease (PD). Previously, we reported the structure of alpha-synuclein fibrils (residues 1–121), composed of two protofibr
Externí odkaz:
https://doaj.org/article/5511896652574ffdab1b13b67a01332c
Autor:
Ricardo Guerrero-Ferreira, Nicholas MI Taylor, Daniel Mona, Philippe Ringler, Matthias E Lauer, Roland Riek, Markus Britschgi, Henning Stahlberg
Publikováno v:
eLife, Vol 7 (2018)
Parkinson’s disease is a progressive neuropathological disorder that belongs to the class of synucleinopathies, in which the protein alpha-synuclein is found at abnormally high concentrations in affected neurons. Its hallmark are intracellular incl
Externí odkaz:
https://doaj.org/article/15f64f3dc9904bdab0ab54b34b6e6cb9
Autor:
Xingqing Xiao, Alicia S Robang, Sudeep Sarma, Justin V Le, Michael E Helmicki, Matthew J Lambert, Ricardo Guerrero-Ferreira, Johana Arboleda-Echavarria, Anant K Paravastu, Carol K Hall
Publikováno v:
PNAS Nexus. 1
Screening amino acid sequence space via experiments to discover peptides that self-assemble into amyloid fibrils is challenging. We have developed a computational peptide assembly design (PepAD) algorithm that enables the discovery of amyloid-forming
Autor:
Laura Rotolo, Daryll Vanover, Nicholas C. Bruno, Hannah E. Peck, Chiara Zurla, Jackelyn Murray, Richard K. Noel, Laura O’Farrell, Mariluz Araínga, Nichole Orr-Burks, Jae Yeon Joo, Lorena C. S. Chaves, Younghun Jung, Jared Beyersdorf, Sanjeev Gumber, Ricardo Guerrero-Ferreira, Santiago Cornejo, Merrilee Thoresen, Alicia K. Olivier, Katie M. Kuo, James C. Gumbart, Amelia R. Woolums, Francois Villinger, Eric R. Lafontaine, Robert J. Hogan, M. G. Finn, Philip J. Santangelo
Publikováno v:
Nature materials.
Messenger RNA has now been used to vaccinate millions of people. However, the diversity of pulmonary pathologies, including infections, genetic disorders, asthma and others, reveals the lung as an important organ to directly target for future RNA the
Publikováno v:
Proceedings of the National Academy of Sciences. 108:12185-12185