Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ricardo G. Espinola"'
Autor:
Irma M. Sainz, Audrey B. Uknis, Robert W. Colman, Albert Adam, Walter K. Long, Robin A. Pixley, Alexis Agelan, John P. Gaughan, Irma Isordia-Salas, Raul A. DeLa Cadena, Ricardo G. Espinola
Publikováno v:
The American Journal of Pathology. 165:969-976
We reported that high-molecular weight kininogen is proangiogenic by releasing bradykinin and that a monoclonal antibody to high-molecular weight kininogen, C11C1, blocked its binding to endothelial cells. We now test if this antibody can prevent art
Autor:
Azzudin E. Gharavi, Silvia S. Pierangeli, Margaret Colden-Stanfield, Xiao Wei Liu, Ricardo G. Espinola, E. Nigel Harris
Publikováno v:
The Journal of Immunology. 163:2922-2927
Antiphospholipid (aPL) Abs are associated with thrombosis, pregnancy loss, and thrombocytopenia in patients with systemic lupus erythematosus or primary antiphospholipid syndrome (APS). β2-Glycoprotein I (β2GPI), a phospholipid-binding serum protei
Autor:
Ricardo G, Espinola, Silvia S, Pierangeli, Azzudin E, Gharavi, E Nigel, Harris, Azzudin E, Ghara
Publikováno v:
Thrombosis and haemostasis. 87(3)
Prothrombotic properties of antiphospholipid (aPL) antibodies may be explained in part by their ability to enhance the activation of platelets pre-treated with low doses of ADP or thrombin. The antimalarial drug hydroxychloroquine (HQ) has been used
Autor:
Robert W. Colman, Irma Isordia-Salas, Ricardo G. Espinola, Harland N. Bradford, Yuchuan Liu, Mohammad M. Khan, Yi Wu, Berhane Ghebrehiwet
Publikováno v:
Blood. 108:1644-1644
Plasma high molecular weight kininogen (HK) is cleaved in inflammatory diseases by kallikrein to cleaved HK (HKa). We have reported that HKa releases cytokines (TNFα , IL-1β , IL-6) and chemokines (IL-8 and MCP-1) from isolated human peripheral blo
Autor:
Berhane Ghebrehiwet, Alice Kuo, Douglas B. Cines, Ricardo G. Espinola, Kusumam Joseph, Robert W. Colman, Robin A. Pixley
Publikováno v:
Blood. 106:2666-2666
The physiologic activation of the plasma kallikrein kinin system (KKS) requires the assembly of these proteins on the cell membrane. High molecular weight kininogen (HK) binds to endothelial cells through an interaction with a multiprotein receptor c
Autor:
Ricardo G. Espinola, Mohammad M. Khan, Harlan N. Bradford, Robert W. Colman, Irma Isordia-Salas
Publikováno v:
Blood. 104:3800-3800
High molecular weight kininogen (HK) is known to bind specifically and saturably to Mac-1 with a Kd = 9–18 nM for neutrophils and to uPAR with a Kd =30 nM for endothelial cells. However, the functional results of HK interaction with Mac-1 or uPAR o
Autor:
Silvia S. Pierangeli, Guillermina Girardi, Mariano Vega‐Ostertag, Xiaowei Liu, Ricardo G. Espinola, Jane Salmon
Publikováno v:
Arthritis & Rheumatism; Jul2005, Vol. 52 Issue 7, p2120-2124, 5p
Autor:
Dardo E. Ferrara, Xiaowei Liu, Ricardo G. Espinola, Pier Luigi Meroni, Imad Abukhalaf, E. Nigel Harris, Silvia S. Pierangeli
Publikováno v:
Arthritis & Rheumatism; Nov2003, Vol. 48 Issue 11, p3272-3279, 8p