Male Sex Is Independently Associated with Faster Disability Accumulation in Relapse-Onset MS but Not in Primary Progressive MS.

Autor: Karen Ann Ribbons, Patrick McElduff, Cavit Boz, Maria Trojano, Guillermo Izquierdo, Pierre Duquette, Marc Girard, Francois Grand'Maison, Raymond Hupperts, Pierre Grammond, Celia Oreja-Guevara, Thor Petersen, Roberto Bergamaschi, Giorgio Giuliani, Michael Barnett, Vincent van Pesch, Maria-Pia Amato, Gerardo Iuliano, Marcela Fiol, Mark Slee, Freek Verheul, Edgardo Cristiano, Ricardo Fernandez-Bolanos, Maria-Laura Saladino, Maria Edite Rio, Jose Cabrera-Gomez, Helmut Butzkueven, Erik van Munster, Leontien Den Braber-Moerland, Daniele La Spitaleri, Alessandra Lugaresi, Vahid Shaygannejad, Orla Gray, Norma Deri, Raed Alroughani, Jeannette Lechner-Scott

Publikováno v: PLoS ONE, Vol 10, Iss 6, p e0122686 (2015)

Multiple Sclerosis is more common in women than men and females have more relapses than men. In a large international cohort we have evaluated the effect of gender on disability accumulation and disease progression to determine if male MS patients ha

Externí odkaz: https://doaj.org/article/6a38050ebee24d48ba782b2cb340dc58

Country, sex, EDSS change and therapy choice independently predict treatment discontinuation in multiple sclerosis and clinically isolated syndrome.

Autor: Claire Meyniel, Timothy Spelman, Vilija G Jokubaitis, Maria Trojano, Guillermo Izquierdo, François Grand'Maison, Celia Oreja-Guevara, Cavit Boz, Alessandra Lugaresi, Marc Girard, Pierre Grammond, Gerardo Iuliano, Marcela Fiol, Jose Antonio Cabrera-Gomez, Ricardo Fernandez-Bolanos, Giorgio Giuliani, Jeannette Lechner-Scott, Edgardo Cristiano, Joseph Herbert, Tatjana Petkovska-Boskova, Roberto Bergamaschi, Vincent van Pesch, Fraser Moore, Norbert Vella, Mark Slee, Vetere Santiago, Michael Barnett, Eva Havrdova, Carolyn Young, Carmen-Adella Sirbu, Mary Tanner, Michelle Rutherford, Helmut Butzkueven, MSBasis Study Group

Publikováno v: PLoS ONE, Vol 7, Iss 6, p e38661 (2012)

OBJECTIVES: We conducted a prospective study, MSBASIS, to assess factors leading to first treatment discontinuation in patients with a clinically isolated syndrome (CIS) and early relapsing-remitting multiple sclerosis (RRMS). METHODS: The MSBASIS St

Externí odkaz: https://doaj.org/article/df6b427842434a779ffb727945fd4d60

BREMSO: a simple score to predict early the natural course of multiple sclerosis

Autor: Guillermo Izquierdo, Pierre Duquette, M. P. Pia Amato, Tim Spelman, Giulia Mallucci, Maria Trojano, Eva Havrdova, Jeannette Lechner-Scott, G. Iuliano, François Grand'Maison, Raed Alroughani, Raymond Hupperts, Edgardo Cristiano, Roberto Bergamaschi, Vahid Shaygannejad, Cristina Montomoli, Thor Petersen, Alessandra Lugaresi, Eugenio Pucci, C Zwanikken, Cavit Boz, Helmut Butzkueven, P. Grammond, Celia Oreja-Guevara, Ricardo Fernandez-Bolanos

Publikováno v: European Journal of Neurology, 22(6), 981-989. Wiley

Background and purpose Early prediction of long-term disease evolution is a major challenge in the management of multiple sclerosis (MS). Our aim was to predict the natural course of MS using the Bayesian Risk Estimate for MS at Onset (BREMSO), which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be881744606abb50909639fdfd95815
https://doi.org/10.1111/ene.12696

Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis

Autor: Raed Alroughani, Maria Pia Amato, Patrizia Sola, Francois Grand'Maison, Eva Havrdova, Pierre Grammond, Ricardo Fernandez Bolanos, Murat Terzi, Bhim Singhal, Tomas Kalincik, Alessandra Lugaresi, Marc Girard, Jeannette Lechner-Scott, Dana Horakova, Freek Verheul, Alexandre Prat, Thor Petersen, Vahid Shaygannejad, Raymond Hupperts, Vilija Jokubaitis, Guillermo Izquierdo, Daniele Spitaleri, Jose Luis Sanchez-Menoyo, Maria Trojano, Franco Granella, Helmut Butzkueven, Mark Slee, Seyed Aidin Sajedi, Cavit Boz, Maria Pia Sormani, Pierre Duquette, Cristina Ramo, Eugenio Pucci, Alessio Signori, Celia Oreja-Guevara, Roberto Bergamaschi, Nastaran Majdinasab, Vincent Van Pesch, Bruce V. Taylor, Stella Hughes, Gerardo Iuliano, Maria Edite Rio

Publikováno v: Signori, A, Izquierdo, G, Lugaresi, A, Hupperts, R, Grand'Maison, F, Sola, P, Horakova, D, Havrdova, E, Prat, A, Girard, M, Duquette, P, Boz, C, Grammond, P, Terzi, M, Singhal, B, Alroughani, R, Petersen, T, Ramo, C, Oreja-Guevara, C, Spitaleri, D, Shaygannejad, V, Butzkueven, H, Kalincik, T, Jokubaitis, V, Slee, M, Fernandez Bolaños, R, Sanchez-Menoyo, J L, Pucci, E, Granella, F, Lechner-Scott, J, Iuliano, G, Hughes, S, Bergamaschi, R, Taylor, B, Verheul, F, Edite Rio, M, Amato, M P, Sajedi, S A, Majdinasab, N, Van Pesch, V, Sormani, M P & Trojano, M 2018, ' Long-term disability trajectories in primary progressive MS patients: A latent class growth analysis ', Multiple sclerosis (Houndmills, Basingstoke, England), vol. 24, no. 5, pp. 642-652 . https://doi.org/10.1177/1352458517703800
MULTIPLE SCLEROSIS JOURNAL
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
instname

Signori, Alessio/0000-0001-6289-9144; Sajedi, Seyed Aidin/0000-0002-6704-9787; Jokubaitis, Vilija G./0000-0002-3942-4340; Shaygannejad, Vahid/0000-0002-6226-0161; Oreja-Guevara, Celia/0000-0002-9221-5716; amato, Maria Pia/0000-0003-3325-3760; Lugares

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6de656a2fc3542a062fbe273ae4142a
https://pubmed.ncbi.nlm.nih.gov/28382837

Risk of relapse phenotype recurrence in multiple sclerosis

Autor: Daniele Spitaleri, Joseph Herbert, Jeannette Lechner-Scott, Bhim Singhal, Tomas Kalincik, Carmen Adella Sirbu, Maria Edite Rio, Marc Girard, Celia Oreja-Guevara, Norbert Vella, Pierre Duquette, Raymond Hupperts, Francois Grand'Maison, Vincent Van Pesch, Alessandra Lugaresi, Maria Pia Amato, Raed Alroughani, Thor Petersen, Marcela Fiol, Gerardo Iuliano, Steve Vucic, Giorgio Giuliani, Ricardo Fernandez-Bolanos, Guillermo Izquierdo, Tatjana Petkovska-Boskova, Freek Verheul, Michael Barnett, Helmut Butzkueven, Mark Paine, Maria Laura Saladino, Jose Antonio Cabrera-Gomez, Erik van Munster, Maria Trojano, Roberto Bergamaschi, S. Flechter, Danny Liew, Orla Gray, Katherine Buzzard, Edgardo Cristiano, Cavit Boz, Mark Slee, Cameron Shaw, Aldo Savino, Vilija Jokubaitis, Csilla Rozsa, Fraser Moore, Pierre Grammond, John Parratt

Publikováno v: Multiple Sclerosis Journal, 20(11), 1511-1522. SAGE Publications Ltd
Kalincik, T, Buzzard, K, Jokubaitis, V, Trojano, M, Duquette, P, Guillermo, I, Girard, M, Lugaresi, A, Grammond, P, Grand'maison, F, Oreja-Guevara, C, Boz, C, Hupperts, R, Petersen, T, Giuliani, G, Iuliano, G, Lechner-Scott, J, Barnett, M, Bergamaschi, R, Van Pesch, V, Amato, M P, van Munster, E, Fernandez-Bolanos, R, Verheul, F, Fiol, M, Cristiano, E, Slee, M, Rio, M E, Spitaleri, D, Alroughani, R, Gray, O, Saladino, M L, Flechter, S, Herbert, J, Cabrera-Gomez, J A, Vella, N, Paine, M, Shaw, C, Moore, F, Vucic, S, Savino, A, Singhal, B, Petkovska-Boskova, T, Parratt, J, Sirbu, C-A, Rozsa, C, Liew, D, Butzkueven, H & on behalf of the MSBase Study Group 2014, ' Risk of relapse phenotype recurrence in multiple sclerosis ', Multiple sclerosis (Houndmills, Basingstoke, England), vol. 20, no. 11, pp. 1511-1522 . https://doi.org/10.1177/1352458514528762

Objectives: The aim was to analyse risk of relapse phenotype recurrence in multiple sclerosis and to characterise the effect of demographic and clinical features on this phenotype. Methods: Information about relapses was collected using MSBase, an in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06ffec7770f062d44783f06e950f90ea
https://doi.org/10.1177/1352458514528762