Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ricardo Calderón-Gonzalez"'
Autor:
David Salcines-Cuevas, Hector Terán-Navarro, Ricardo Calderón-Gonzalez, Paula Torres-Rodriguez, Raquel Tobes, Manuel Fresno, Jorge Calvo-Montes, I. Concepción Pérez Del Molino-Bernal, Sonsoles Yañez-Diaz, Carmen Alvarez-Dominguez
Publikováno v:
Vaccines, Vol 9, Iss 3, p 269 (2021)
Universal vaccines can be prepared with antigens common to different pathogens. In this regard, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is a common virulence factor among pathogenic bacteria of the genera Listeria, Mycobacterium and Stre
Externí odkaz:
https://doaj.org/article/24fa41b5074440188a98730e020226d7
Autor:
Ricardo Calderón-Gonzalez, Héctor Terán-Navarro, Elisabet Frande-Cabanes, Eva Ferrández-Fernández, Javier Freire, Soledad Penadés, Marco Marradi, Isabel García, Javier Gomez-Román, Sonsoles Yañez-Díaz, Carmen Álvarez-Domínguez
Publikováno v:
Nanomaterials, Vol 6, Iss 8, p 151 (2016)
Listeriosis is a fatal infection for fetuses and newborns with two clinical main morbidities in the neonatal period, meningitis and diffused cutaneous lesions. In this study, we vaccinated pregnant females with two gold glyconanoparticles (GNP) loade
Externí odkaz:
https://doaj.org/article/0e80f5a0e21b4c068b6af1c09dea865c
Autor:
Ricardo Calderon-Gonzalez, Amy Dumigan, Joana Sá-Pessoa, Adrien Kissenpfennig, José A Bengoechea
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011900 (2024)
In vivo single-cell approaches have transformed our understanding of the immune populations in tissues. Mass cytometry (CyTOF), that combines the resolution of mass spectrometry with the ability to conduct multiplexed measurements of cell molecules a
Externí odkaz:
https://doaj.org/article/d6061d32b20e4cbfba30153ab11aeb30
Autor:
Amy Dumigan, Oisin Cappa, Brenda Morris, Joana Sá Pessoa, Ricardo Calderon‐Gonzalez, Grant Mills, Rebecca Lancaster, David Simpson, Adrien Kissenpfennig, Jose A Bengoechea
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 12, Pp 1-26 (2022)
Abstract The strategies deployed by antibiotic‐resistant bacteria to counteract host defences are poorly understood. Here, we elucidate a novel host–pathogen interaction resulting in skewing lung macrophage polarisation by the human pathogen Kleb
Externí odkaz:
https://doaj.org/article/2680c8973c77459980aed84318c4934c
Autor:
Marcin Baran, Claudia Feriotti, Aoife McGinley, Simon R. Carlile, Zhaozhao Jiang, Ricardo Calderon-Gonzalez, Amy Dumigan, Joana Sá-Pessoa, Caroline E. Sutton, Jay Kearney, Rachel M. McLoughlin, Kingston H.G. Mills, Katherine A. Fitzgerald, Jose A. Bengeochea, Andrew G. Bowie
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112341- (2023)
Summary: PYHIN proteins AIM2 and IFI204 sense pathogen DNA, while other PYHINs have been shown to regulate host gene expression through as-yet unclear mechanisms. We characterize mouse PYHIN IFI207, which we find is not involved in DNA sensing but ra
Externí odkaz:
https://doaj.org/article/f56f8dac50b94ee2b449ad3b6f42ddc8
Autor:
Ricardo Calderon-Gonzalez, Alix Lee, Guillermo Lopez-Campos, Steven J. Hancock, Joana Sa-Pessoa, Amy Dumigan, Ronan McMullan, Eric L. Campbell, Jose A. Bengoechea
Publikováno v:
mBio, Vol 14, Iss 1 (2023)
ABSTRACT Klebsiella pneumoniae is a leading cause of nosocomial and community acquired infections, making K. pneumoniae the pathogen that is associated with the second largest number of deaths attributed to any antibiotic resistant infection. K. pneu
Externí odkaz:
https://doaj.org/article/8d74ee6a8a224fe895fcd318972ecd86
Autor:
Hector Teran-Navarro, David Salcines-Cuevas, Ricardo Calderon-Gonzalez, Raquel Tobes, Jorge Calvo-Montes, Inmaculada Concepción Pérez-Del Molino Bernal, Sonsoles Yañez-Diaz, Manuel Fresno, Carmen Alvarez-Dominguez
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Cross-reactive vaccines recognize common molecular patterns in pathogens and are able to confer broad spectrum protection against different infections. Antigens common to pathogenic bacteria that induce broad immune responses, such as the glyceraldeh
Externí odkaz:
https://doaj.org/article/a41c4dc468da4c2d89cb65d45e5a75db
Autor:
Carmen Alvarez-Dominguez, David Salcines-Cuevas, Héctor Teran-Navarro, Ricardo Calderon-Gonzalez, Raquel Tobes, Isabel Garcia, Santiago Grijalvo, Alberto Paradela, Asunción Seoane, Felix J. Sangari, Manuel Fresno, Jorge Calvo-Montes, I. Concepción Pérez Del Molino Bernal, Sonsoles Yañez-Diaz
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
The glycolytic enzyme and bacterial virulence factor of Listeria monocytogenes, the glyceraldehyde-3-phosphate dehydrogenase (GAPDH, Lmo2459), ADP-ribosylated the small GTPase, Rab5a, and blocked phagosome maturation. This inhibitory activity localiz
Externí odkaz:
https://doaj.org/article/6a550dd2530d4337a3f0c90dd9cafc5d
Autor:
Hector Terán-Navarro, Ricardo Calderon-Gonzalez, David Salcines-Cuevas, Isabel García, Marco Marradi, Javier Freire, Erwan Salmon, Mar Portillo-Gonzalez, Elisabet Frande-Cabanes, Almudena García-Castaño, Virginia Martinez-Callejo, Javier Gomez-Roman, Raquel Tobes, Fernando Rivera, Sonsoles Yañez-Diaz, Carmen Álvarez-Domínguez
Publikováno v:
OncoImmunology, Vol 8, Iss 2 (2019)
Gold glyconanoparticles loaded with the listeriolysin O peptide 91–99 (GNP-LLO91-99), a bacterial peptide with anti-metastatic properties, are vaccine delivery platforms facilitating immune cell targeting and increasing antigen loading. Here, we pr
Externí odkaz:
https://doaj.org/article/1f27fc9b9d0441b78d7ab7e29e2b2a5b
Autor:
Lucia Bronchalo-Vicente, Estela Rodriguez-Del Rio, Javier Freire, Ricardo Calderon-Gonzalez, Elisabet Frande-Cabanes, Jose Javier Gomez-Roman, Hector Fernández-Llaca, Sonsoles Yañez-Diaz, Carmen Alvarez-Dominguez
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0117923 (2015)
Listeria monocytogenes is a gram-positive bacteria and human pathogen widely used in cancer immunotherapy because of its capacity to induce a specific cytotoxic T cell response in tumours. This bacterial pathogen strongly induces innate and specific
Externí odkaz:
https://doaj.org/article/c2637bd9c4304389a51064a5074524b4