Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ricardo Armisén"'
Autor:
Javiera Garrido, Yanara Bernal, Evelin González, Alejandro Blanco, Gonzalo Sepúlveda-Hermosilla, Matías Freire, Karen Oróstica, Solange Rivas, Katherine Marcelain, Gareth Owen, Carolina Ibañez, Alejandro Corvalan, Marcelo Garrido, Rodrigo Assar, Rodrigo Lizana, Javier Cáceres-Molina, Diego Ampuero, Liliana Ramos, Paola Pérez, Osvaldo Aren, Sara Chernilo, Cristina Fernández, María Loreto Spencer, Jacqueline Flores Aguila, Giuliano Bernal Dossetto, Mónica Ahumada Olea, Germán Rasse, Carolina Sánchez, Maria Galli de Amorim, Thais F. Bartelli, Diana Noronha Nunes, Emmanuel Dias-Neto, Helano C. Freitas, Ricardo Armisén
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Background Tobacco use is one of the main risk factors for Lung Cancer (LC) development. However, about 10–20% of those diagnosed with the disease are never-smokers. For Non-Small Cell Lung Cancer (NSCLC) there are clear differences in bot
Externí odkaz:
https://doaj.org/article/299f116c68364c9a8cb95e5dde0ba0e8
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7424 (2024)
Epitranscriptomics is a field that delves into post-transcriptional changes. Among these modifications, the conversion of adenosine to inosine, traduced as guanosine (A>I(G)), is one of the known RNA-editing mechanisms, catalyzed by ADARs. This type
Externí odkaz:
https://doaj.org/article/f93b6bb764f04f10807470b6eccf0a5a
Autor:
Camilo Tapia-Valladares, Guillermo Valenzuela, Evelin González, Ignacio Maureira, Jessica Toro, Matías Freire, Gonzalo Sepúlveda-Hermosilla, Diego Ampuero, Alejandro Blanco, Iván Gallegos, Fernanda Morales, José I. Erices, Olga Barajas, Mónica Ahumada, Héctor R. Contreras, Jaime González, Ricardo Armisén, Katherine Marcelain
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 9, p 4695 (2024)
Colorectal cancer (CRC) is the second leading cause of cancer deaths globally. While ethnic differences in driver gene mutations have been documented, the South American population remains understudied at the genomic level, despite facing a rising bu
Externí odkaz:
https://doaj.org/article/956dc6976f554e7ca601afb0e64c2e5e
Autor:
Yanara A. Bernal, Alejandro Blanco, Eduardo A. Sagredo, Karen Oróstica, Ivan Alfaro, Katherine Marcelain, Ricardo Armisén
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 728 (2024)
Dysregulated A>I(G) RNA editing, which is mainly catalyzed by ADAR1 and is a type of post-transcriptional modification, has been linked to cancer. A low response to therapy in breast cancer (BC) is a significant contributor to mortality. However, it
Externí odkaz:
https://doaj.org/article/cc72029d95214edc80ecefec576c3c16
Autor:
Karen Y. Oróstica, Juan Saez-Hidalgo, Pamela R. de Santiago, Solange Rivas, Sebastian Contreras, Gonzalo Navarro, Juan A. Asenjo, Álvaro Olivera-Nappa, Ricardo Armisén
Publikováno v:
Journal of Translational Medicine, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background Recently, extensive cancer genomic studies have revealed mutational and clinical data of large cohorts of cancer patients. For example, the Pan-Lung Cancer 2016 dataset (part of The Cancer Genome Atlas project), summarises the mut
Externí odkaz:
https://doaj.org/article/48c75e6dd127492abe9641717a22dadd
Autor:
Solange Rivas, Ricardo Armisén
Publikováno v:
Revista Médica Clínica Las Condes, Vol 33, Iss 1, Pp 25-35 (2022)
Resumen: El cáncer se origina por mutaciones conductoras que entregan ventajas en el crecimiento celular, por medio de la inhibición de los puntos de control y la activación exacerbada de vías de señalización involucradas en la sobrevivencia y
Externí odkaz:
https://doaj.org/article/27a860637a1e41c8b6255fda05ed3bdf
Autor:
Miguel Cordova-Delgado, María Loreto Bravo, Elisa Cumsille, Charlotte N. Hill, Matías Muñoz-Medel, Mauricio P. Pinto, Ignacio N. Retamal, María A. Lavanderos, Juan Francisco Miquel, Maria Rodriguez-Fernandez, Yuwei Liao, Zhiguang Li, Alejandro H. Corvalán, Ricardo Armisén, Marcelo Garrido, Luis A. Quiñones, Gareth I. Owen
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)
Abstract Background Fluoropyrimidine plus platinum chemotherapy remains the standard first line treatment for gastric cancer (GC). Guidelines exist for the clinical interpretation of four DPYD genotypes related to severe fluoropyrimidine toxicity wit
Externí odkaz:
https://doaj.org/article/63e96e3bc013444db64e630114bf6b8d
Publikováno v:
PLoS ONE, Vol 17, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/fd2ebcbb8dd84eb484692bf29a539119
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13898 (2022)
The MET gene, known as MET proto-oncogene receptor tyrosine kinase, was first identified to induce tumor cell migration, invasion, and proliferation/survival through canonical RAS-CDC42-PAK-Rho kinase, RAS-MAPK, PI3K-AKT-mTOR, and β-catenin signalin
Externí odkaz:
https://doaj.org/article/a20d1bd30a44428892f7df4e6851379c
Autor:
Eduardo A. Sagredo, Alejandro Blanco, Alfredo I. Sagredo, Paola Pérez, Gonzalo Sepúlveda-Hermosilla, Fernanda Morales, Bettina Müller, Ricardo Verdugo, Katherine Marcelain, Olivier Harismendy, Ricardo Armisén
Publikováno v:
Biological Research, Vol 51, Iss 1, Pp 1-10 (2018)
Abstract Background Whole transcriptome RNA variant analyses have shown that adenosine deaminases acting on RNA (ADAR) enzymes modify a large proportion of cellular RNAs, contributing to transcriptome diversity and cancer evolution. Despite the advan
Externí odkaz:
https://doaj.org/article/a5c38d40f9104f5db1a081e849477aff