Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Ricardo A. Vialle"'
Autor:
Hadley W. Ressler, Jack Humphrey, Ricardo A. Vialle, Bergan Babrowicz, Shrishtee Kandoi, Towfique Raj, Dennis W. Dickson, Nilüfer Ertekin-Taner, John F. Crary, Kurt Farrell
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-12 (2024)
Abstract Progressive supranuclear palsy (PSP) is a neurodegenerative movement and cognitive disorder characterized by abnormal accumulation of the microtubule-associated protein tau in the brain. Biochemically, inclusions in PSP are enriched for tau
Externí odkaz:
https://doaj.org/article/1fc028332e0f4a12a16271fb90f08338
Autor:
Francine Grodstein, Bernardo Lemos, Jingyun Yang, Katia de Paiva Lopes, Ricardo A. Vialle, Nicholas Seyfried, Yanling Wang, Gemma Shireby, Eilis Hannon, Alan Thomas, Keeley Brookes, Jonathan Mill, Philip L. De Jager, David A. Bennett
Publikováno v:
Epigenetics, Vol 19, Iss 1 (2024)
The cortical epigenetic clock was developed in brain tissue as a biomarker of brain aging. As one way to identify mechanisms underlying aging, we conducted a GWAS of cortical age. We leveraged postmortem cortex tissue and genotyping array data from 6
Externí odkaz:
https://doaj.org/article/3bd3ed164ebf4211abfa1877dd14702f
Autor:
Giulietta Maria Riboldi, Ricardo A. Vialle, Elisa Navarro, Evan Udine, Katia de Paiva Lopes, Jack Humphrey, Amanda Allan, Madison Parks, Brooklyn Henderson, Kelly Astudillo, Charalambos Argyrou, Maojuan Zhuang, Tamjeed Sikder, J. Oriol Narcis, Shilpa Dilip Kumar, William Janssen, Allison Sowa, Giacomo P. Comi, Alessio Di Fonzo, John F. Crary, Steven J. Frucht, Towfique Raj
Publikováno v:
Molecular Neurodegeneration, Vol 17, Iss 1, Pp 1-17 (2022)
Abstract Background Genetic mutations in beta-glucocerebrosidase (GBA) represent the major genetic risk factor for Parkinson’s disease (PD). GBA participates in both the endo-lysosomal pathway and the immune response, two important mechanisms invol
Externí odkaz:
https://doaj.org/article/dbe17cf7cdea4ab8b6a5e2418d509f7c
Autor:
Bruno Thiago de Lima Nichio, Aryel Marlus Repula de Oliveira, Camilla Reginatto de Pierri, Leticia Graziela Costa Santos, Alexandre Quadros Lejambre, Ricardo Assunção Vialle, Nilson Antônio da Rocha Coimbra, Dieval Guizelini, Jeroniza Nunes Marchaukoski, Fabio de Oliveira Pedrosa, Roberto Tadeu Raittz
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Clustering methods are essential to partitioning biological samples being useful to minimize the information complexity in large datasets. Tools in this context usually generates data with greed algorithms that solves some Data Mi
Externí odkaz:
https://doaj.org/article/b2773d0fe0e344969419c808173a62fc
Publikováno v:
Nature Neuroscience. 25:504-514
Autor:
Katia de Paiva Lopes, Francisco José Campos-Laborie, Ricardo Assunção Vialle, José Miguel Ortega, Javier De Las Rivas
Publikováno v:
BMC Genomics, Vol 17, Iss S8, Pp 337-349 (2016)
Abstract Background The development of large-scale technologies for quantitative transcriptomics has enabled comprehensive analysis of the gene expression profiles in complete genomes. RNA-Seq allows the measurement of gene expression levels in a man
Externí odkaz:
https://doaj.org/article/79ff44c8ce234207bfdcf9f8da9cf765
Autor:
John F. Crary, Katia de Paiva Lopes, Bradley T. Hyman, Manav Kapoor, Gloriia Novikova, Jonathan D. Glass, Valeriy Borukov, Hadley Walsh, Erin E. Franklin, Johannes Attems, Sara Shuldberg, Shea J. Andrews, Thomas J. Montine, Julie A. Schneider, Jonathan D. Cherry, C. Dirk Keene, Towfique Raj, Charles L. White, Thor D. Stein, Evan Udine, Gai Ayalon, Thao Pham, Maria M. Corrada, Weijing Tang, Ann C. McKee, Bess Frost, Marco M. Hefti, Qinwen Mao, Lei Yu, Patrick R. Hof, Peter T. Nelson, Elias M. Gonzalez, Alan E. Renton, Corey T. McMillan, Jack Humphrey, Natalia Han, Margaret E. Flanagan, SoongHo Kim, Etty Cortes, Megan A. Iida, Inma Cobos, Jeff Metcalf, Sandra Weintraub, Julie Hunkapiller, Diana K. Dangoor, Robert A. Rissman, Marcos Otero-Garcia, John Q. Trojanowski, Dushyant P. Purohit, Caitlin S. Latimer, Marla Gearing, Claudia H. Kawas, Kathryn R. Bowles, Wayne W. Poon, Brian Fulton-Howard, Edoardo Marcora, Alison Goate, Alicia Casella, Tushar Bhangale, Richard J. Perrin, Herbert T. Cohen, Bahar Salehi, Gabor G. Kovacs, Andy F. Teich, Mary Sano, Jamie M. Walker, Dennis W. Dickson, Randy Woltjer, Kristen Whitney, M.-Marsel Mesulam, Ricardo Assunção Vialle, Peter Fischer, Kurt Farrell, Jean-Paul Vonsattel, Cheick T. Sissoko, Vahram Haroutunian, Sam Gandy, Mirjam I. Lutz, Matthew P. Frosch, Nigel J. Cairns, Melissa E. Murray, Robert R. Graham, David A. Wolk, Juan C. Troncoso, Garrett Wong, Julia Kofler, Edward B. Lee, Timothy E. Richardson, Thomas G. Beach
Publikováno v:
Acta Neuropathol
Primary age-related tauopathy (PART) is a neurodegenerative pathology with features distinct from but also overlapping with Alzheimer disease (AD). While both exhibit Alzheimer-type temporal lobe neurofibrillary degeneration alongside amnestic cognit
Autor:
Maojuan Zhuang, Evan Udine, Roberto A. Ortega, Susan Bressman, Madison Parks, Deborah Raymond, Ritesh A. Ramdhani, Vicki Shanker, Katia de Paiva Lopes, Michael J. Chao, John F. Crary, Steven J. Frucht, Lotje de Witte, Gijsje J. L. J. Snijders, Matthew Swan, Towfique Raj, Elisa Navarro, Ruth H. Walker, Ana C. Pereira, Amanda Allan, Tim Ahfeldt, Jack Humphrey, Charalambos Argyrou, Sarah Simon, Winona Tse, Brooklyn Henderson, Sonya Elango, Rachel Saunders-Pullman, Alison Goate, Tamjeed Sikder, Brian M. Schilder, Carolyn W. Zhu, Ricardo Assunção Vialle, Kurt Farrell, Giulietta Riboldi, Mary Sano
Publikováno v:
Nat Aging
An increasing number of identified Parkinson’s disease (PD) risk loci contain genes highly expressed in innate immune cells, yet their role in pathology is not understood. We hypothesized that PD susceptibility genes modulate disease risk by influe
Autor:
Ricardo A. Vialle, Towfique Raj
Publikováno v:
Neuromethods ISBN: 9781071623565
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5aecefac34773ddd4a7aa4b894819753
https://doi.org/10.1007/978-1-0716-2357-2_1
https://doi.org/10.1007/978-1-0716-2357-2_1
Autor:
Giulietta Maria Riboldi, Ricardo A Vialle, Elisa Navarro, Evan Udine, Katia de Paiva Lopes, Amanda Allan, Madison Parks, Brooklyn Henderson, Kelly Astudillo, Charalambos Argyrou, Maojuan Zhuang, Tamjeed Sikder, Oriol J. Narcis, Shilpa Dilip Kumar, William Janssen, Allison Sowa, Giacomo P Comi, Alessio Di Fonzo, John F. Crary, Steven J Frucht, Towfique Raj
BackgroundGenetic mutations in the beta-glucocerebrosidase (GCase), GBA gene, represent the major genetic risk factor for Parkinson’s disease (PD). The function of the GBA gene is at the crossroads between the endo-lysosomal pathway and the immune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d8f6d03fb7658e6d0e9b62e356d87686
https://doi.org/10.1101/2021.12.22.21267952
https://doi.org/10.1101/2021.12.22.21267952