Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Ricardo, Zamel"'
Autor:
Gaowa Saren, Aaron Wong, Yun-Bi Lu, Cristina Baciu, Wenyong Zhou, Ricardo Zamel, Sahar Soltanieh, Junichi Sugihara, Mingyao Liu
Publikováno v:
Cells, Vol 10, Iss 10, p 2713 (2021)
Current understanding of mechanisms of ischemia-reperfusion-induced lung injury during lung preservation and transplantation is mainly based on clinical observations and animal studies. Herein, we used cell and systems biology approaches to explore t
Externí odkaz:
https://doaj.org/article/4be11fc175e44188a3a354569d3e788a
Autor:
David L. Duffy, Noe Zamel, Kenneth R. Chapman, Ricardo Zamel, Nicholas G. Martin, Katherine A. Siminovitch
Publikováno v:
Twin Research and Human Genetics. 22:277-282
A high prevalence of asthma has been documented among the inhabitants of Tristan da Cunha, an isolated island in the South Atlantic. The population derives from just 28 founders. We performed lung function testing, including methacholine inhalation c
Autor:
Yidan Zhao, Jenny Peng, Catherine Lu, Michael Hsin, Marco Mura, Licun Wu, Lei Chu, Ricardo Zamel, Tiago Machuca, Thomas Waddell, Mingyao Liu, Shaf Keshavjee, John Granton, Marc de Perrot
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e88727 (2014)
Although multiple gene and protein expression have been extensively profiled in human pulmonary arterial hypertension (PAH), the mechanism for the development and progression of pulmonary hypertension remains elusive. Analysis of the global metabolom
Externí odkaz:
https://doaj.org/article/247447fa48864bcd8529fff7219f5743
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e64182 (2013)
A variety of airborne pathogens can induce inflammatory responses in airway epithelial cells, which is a crucial component of host defence. However, excessive inflammatory responses and chronic inflammation also contribute to different diseases of th
Externí odkaz:
https://doaj.org/article/0036a868bb9a4ead965f679c4537cb09
Autor:
Cristina Baciu, Yang Chen, Marcelo Cypel, Mingyao Liu, Tiago N. Machuca, Jason Shin, Ricardo Zamel, Shaf Keshavjee, Michael K. Hsin, Jonathan C. Yeung
Publikováno v:
The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. 40(6)
Background Normothermic ex vivo lung perfusion (EVLP) allows for functional assessment of donor lungs; thus has increased the use of marginal lungs for transplantation. To extend EVLP for advanced organ reconditioning and regenerative interventions,
Autor:
D.R. Darley, Ricardo Zamel, Tereza Martinu, David M. Hwang, Prodipto Pal, Liran Levy, Jussi Tikkanen, William Klement, Shaf Keshavjee, Jin Ma, Pierre Fiset, Lianne G. Singer, George Tomlinson, Ella Huszti
Publikováno v:
Transplant international : official journal of the European Society for Organ TransplantationReferences. 34(1)
Long-term outcomes after lung transplantation remain inferior to those of other solid organ groups. The significance of eosinophils detected on transbronchial biopsies (TBBx) after lung transplantation and their relationship to long-term outcomes rem
Autor:
Xiao-Hui Bai, Christina Lu, Mingyao Liu, Hyunhee Kim, Shaf Keshavjee, Ricardo Zamel, Sara Keshavjee
Publikováno v:
American Journal of Physiology-Lung Cellular and Molecular Physiology. 315:L595-L608
Ischemia-reperfusion (I/R)-induced lung injury undermines lung transplantation (LTx) outcomes by predisposing lung grafts to primary graft dysfunction (PGD). Necrosis is a feature of I/R lung injury. However, regulated necrosis (RN) with specific sig
Autor:
Marcelo Cypel, Yohei Taniguchi, Manyin Chen, Shaf Keshavjee, Ricardo Zamel, Tatsuaki Watanabe, L. Caldarone, Constantine Harmantas, H. Gokhale, Hei Yu Andrew Cheung, Mamoru Takahashi, Yui Watanabe, R. Qaqish, Mingyao Liu, Z. Guan
Publikováno v:
The Journal of thoracic and cardiovascular surgery. 161(6)
Objectives Ex vivo lung perfusion provides an innovative method to assess and repair donor lungs. The current Toronto ex vivo lung perfusion protocol can reliably and reproducibly preserve lungs for 12 hours. A longer ex vivo lung perfusion preservat
Autor:
Marcelo Cypel, K. Hashimoto, Tomohito Saito, Hyunhee Kim, Tiago N. Machuca, Thomas K. Waddell, Stephen C. Juvet, Mingyao Liu, Michael Hsin, Shaf Keshavjee, Ricardo Zamel
Publikováno v:
The Journal of Heart and Lung Transplantation. 37:240-249
Ex vivo lung perfusion (EVLP) enables assessment of marginal donor lungs for transplantation, with similar clinical outcomes to conventional lung transplantation. We investigated whether cell death-related proteins in the EVLP perfusate could predict
Autor:
Aaron, Wong, Ricardo, Zamel, Jonathan, Yeung, Gary D, Bader, Claudia C, Dos Santos, Xiaohui, Bai, Yubo, Wang, Shaf, Keshavjee, Mingyao, Liu
Publikováno v:
The European respiratory journal. 55(4)
TheRetrospective transcriptomics analyses were performed with peripheral tissue biopsies from "donation after brain death" lungs, with 46 pre-/post-transplant pairs and 49 pre-/post-EVLP pairs. Pathway analysis was used to identify and compare the re