Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Ricard Mesía"'
Publikováno v:
Pharmacology Research & Perspectives, Vol 12, Iss 1, Pp n/a-n/a (2024)
Abstract Off‐label use (OLU) is quite common in oncology due to the complexity of cancer and the time‐consuming regulatory process. However, outcomes of OLU in cancer treatment remain unclear. This study aimed to evaluate the overall survival (OS
Externí odkaz:
https://doaj.org/article/e641a54fb2d442639d55294939dbeaa6
Autor:
Sandra Fontanals, Anna Esteve, Andrea González, Cristina Ibáñez, Javier Martínez, Ricard Mesía, Ana Clopés
Publikováno v:
Cancer Medicine, Vol 12, Iss 16, Pp 17112-17125 (2023)
Abstract Purpose Medicines in special situations (MSS) refer to off‐label or to unlicensed drugs under investigation (compassionate use). Our objectives were to evaluate characteristics and to estimate overall survival (OS), event‐free survival (
Externí odkaz:
https://doaj.org/article/e109919815c54fed8ef7e66d141585d2
Autor:
Juan A. Marín-Jiménez, Marc Oliva, Paloma Peinado Martín, Santiago Cabezas-Camarero, Maria Plana Serrahima, Gonzalo Vázquez Masedo, Alicia Lozano Borbalas, María N. Cabrera Martín, Anna Esteve, María C. Iglesias Moreno, Esther Vilajosana Altamis, Lorena Arribas Hortigüela, Miren Taberna Sanz, Pedro Pérez-Segura, Ricard Mesía
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectivesInduction chemotherapy (ICT) followed by definitive treatment is an accepted non-surgical approach for locoregionally advanced head and neck squamous cell carcinoma (LA-HNSCC). However, ICT remains a challenge for cisplatin-unfit patients.
Externí odkaz:
https://doaj.org/article/9d6af13842bf47e6b926fa2e5a09c1cc
Autor:
Miren Taberna, Francisco Gil Moncayo, Enric Jané-Salas, Maite Antonio, Lorena Arribas, Esther Vilajosana, Elisabet Peralvez Torres, Ricard Mesía
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
The core function of a multidisciplinary team (MDT) is to bring together a group of healthcare professionals from different fields in order to determine patients' treatment plan. Most of head and neck cancer (HNC) units are currently led by MDTs that
Externí odkaz:
https://doaj.org/article/69a375cf4f394954b2d6310a6318f537
Autor:
Jesús García-Foncillas, Antonio Tejera-Vaquerizo, Onofre Sanmartín, Federico Rojo, Javier Mestre, Salvador Martín, Ignacio Azinovic, Ricard Mesía
Publikováno v:
Cancers, Vol 14, Iss 3, p 629 (2022)
Cutaneous squamous cell carcinoma (cSCC) is the second most common form of skin cancer, the incidence of which has risen over the last years. Although cSCC rarely metastasizes, early detection and treatment of primary tumours are critical to limit pr
Externí odkaz:
https://doaj.org/article/e9db2bbe2afa487d9883a1adbbb1899e
Autor:
Eudald Felip, Lucía Gutiérrez-Chamorro, Maica Gómez, Edurne Garcia-Vidal, Margarita Romeo, Teresa Morán, Laura Layos, Laia Pérez-Roca, Eva Riveira-Muñoz, Bonaventura Clotet, Pedro Luis Fernandez, Ricard Mesía, Anna Martínez-Cardús, Ester Ballana, Mireia Margelí
Publikováno v:
Cancers, Vol 14, Iss 3, p 641 (2022)
SAMHD1 is a deoxynucleotide triphosphate (dNTP) triphosphohydrolase with important roles in the control of cell proliferation and apoptosis, either through the regulation of intracellular dNTPs levels or the modulation of the DNA damage response. How
Externí odkaz:
https://doaj.org/article/c6e5a79cb58843868b821bc667c24dd2
Autor:
Javier Fernández-Mateos, Raquel Seijas-Tamayo, Juan Carlos Adansa Klain, Miguel Pastor Borgoñón, Elisabeth Pérez-Ruiz, Ricard Mesía, Elvira del Barco, Carmen Salvador Coloma, Antonio Rueda Dominguez, Javier Caballero Daroqui, Encarnación Fernández Ruiz, Juan Jesús Cruz-Hernández, Rogelio González-Sarmiento
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-8 (2017)
Abstract Head and neck squamous cell carcinoma (HNSCC) is the sixth cancer on incidence worldwide. Tobacco and alcohol consumption are the most classical risk factors associated with its development. Autophagy process has a dual effect both in tumour
Externí odkaz:
https://doaj.org/article/2a6d4d6151124d12a8c1eba89b44d361
Autor:
Joël Guigay, Makoto Tahara, Lisa Licitra, Ulrich Keilholz, Signe Friesland, Pauline Witzler, Ricard Mesía
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
The addition of cetuximab to platinum-based chemotherapy (cisplatin or carboplatin plus 5-fluorouracil [5-FU]), followed by maintenance cetuximab until disease progression (EXTREME), resulted in the first regimen to yield significantly improved survi
Externí odkaz:
https://doaj.org/article/fa7aba0c1d3d42bb82e94950f56ad59a
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Cetuximab remains to date the only targeted therapy approved for the treatment of head and neck squamous cell carcinoma (HNSCC). The EGFR pathway plays a key role in the tumorigenesis and progression of this disease as well as in the resistance to ra
Externí odkaz:
https://doaj.org/article/11ea86bd11c94547877e656633167bac
Autor:
Miren Taberna, Montserrat Torres, María Alejo, Marisa Mena, Sara Tous, Sandra Marquez, Miquel A. Pavón, Xavier León, Jacinto García, Marta Guix, Rafael Hijano, Teresa Bonfill, Antón Aguilà, Alicia Lozano, Ricard Mesía, Laia Alemany, Ignacio G. Bravo
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
Background: Anti-epidermal-growth-factor-receptor (EGFR) therapies in combination with radiotherapy are being studied on de-escalation clinical trials for HPV-related oropharyngeal cancer (OPC) patients. The HPV16-E5 oncoprotein increases recycling o
Externí odkaz:
https://doaj.org/article/3c163deb796b4698b73b83a42ed031ca