Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Ribosomes/metabolism"'
Autor:
Genki Akanuma, Fabio Trebini, Pavel Kudrin, Hiraku Takada, Rikinori Murayama, Abel Garcia-Pino, Julien Caballero-Montes, Steffi Jimmy, Vasili Hauryliuk, Mohammad Roghanian, Katleen Van Nerom
Publikováno v:
Nucleic Acids Research
Nucleic acids research, 49 (1
Nucleic acids research, 49 (1
In the Gram-positive Firmicute bacterium Bacillus subtilis, amino acid starvation induces synthesis of the alarmone (p)ppGpp by the RelA/SpoT Homolog factor Rel. This bifunctional enzyme is capable of both synthesizing and hydrolysing (p)ppGpp. To de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::030d20a8da5634a5b51c145d1d4d82db
http://europepmc.org/articles/PMC7797070
http://europepmc.org/articles/PMC7797070
Autor:
Eli Schwartz, Yoav Peleg, Alicia Rojas, Ariel Rudik, Hila Ben Ami Pilo, Ana Claudia Torrecilhas, Ziv Porat, Netta Nir, Or-Yam Revach, Dror Avni, Tal Havkin-Solomon, Abel Cruz Camacho, Thomas Zillinger, Andrew G. Bowie, Carmit Levy, Ron Rotkopf, Aryeh Solomon, Tal Block Tamin, Antonella Di Pizio, Paula Abou Karam, Reinat Nevo, Edo Kiper, Esther N. M. Nolte-‘t Hoen, Gunther Hartmann, Motti Gerlic, Rivka Dikstein, Anna Rivkin, Neils B. Quashie, Yifat Ofir-Birin, Neta Regev-Rudzki
Publikováno v:
Nature Communications, 12(1), 1. Nature Publishing Group
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Pathogens are thought to use host molecular cues to control when to initiate life-cycle transitions, but these signals are mostly unknown, particularly for the parasitic disease malaria caused by Plasmodium falciparum. The chemokine CXCL10 is present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a1064e45a182dff5f26e2cfecc1f47d
https://dspace.library.uu.nl/handle/1874/416422
https://dspace.library.uu.nl/handle/1874/416422
Publikováno v:
Communications biology, vol. 4, no. 1, pp. 715
While SARS-CoV-2 is causing modern human history's most serious health crisis and upending our way of life, clinical and basic research on the virus is advancing rapidly, leading to fascinating discoveries. Two studies have revealed how the viral vir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::c361f200efec89ca4bb5738148483d32
https://serval.unil.ch/notice/serval:BIB_AE1D3DB18448
https://serval.unil.ch/notice/serval:BIB_AE1D3DB18448
Autor:
Gary Loughran, Jeffrey W. Bode, Pramod R. Bhatt, Kate M. O’Connor, David Gatfield, Annika Kratzel, Volker Thiel, Nenad Ban, John F. Atkins, René Dreos, Marc Leibundgut, Romane Meurs, Alain Scaiola, Angus McMillan
Publikováno v:
Science (New York, N.y.)
Science, vol. 372, no. 6548, pp. 1306-1313
Science, vol. 372, no. 6548, pp. 1306-1313
Shifting frames to make more proteins Severe acute respiratory syndrome coronavirus 2 critically depends on the ribosomal frameshifting that occurs between two large open reading frames in its genomic RNA for expression of viral replicase. Programmed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b048a2925451cc1fd784af0742d4b762
Autor:
Jurada, Deana
Cilj istraživanja: Heterozigotne mutacije RP u sisavaca uzrokuju razvojne anomalije i zloćudne tumore. Inaktivacija supresora tumora p53 u tim uvjetima sprječava nastanak razvojnih anomalija i potiče razvoj zloćudnih tumora. Međutim, molekularn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4121::843f5354bf0dbbd20724ec907ba84f84
https://repository.medri.uniri.hr/islandora/object/medri:4309
https://repository.medri.uniri.hr/islandora/object/medri:4309
Publikováno v:
Methods in Molecular Biology. 1649:385-404
mRNA translation is a key step in decoding the genetic information stored in DNA. Regulation of translation efficiency contributes to gene expression control and is therefore important for cell fate and function. Here, we describe a recently develope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dris___00893::e80e72ed5d9bd36fab3c507bb0ff8def
https://hdl.handle.net/20.500.11755/a7144e14-6493-458b-b990-3e27348ef3d4
https://hdl.handle.net/20.500.11755/a7144e14-6493-458b-b990-3e27348ef3d4
Autor:
Martijn A. van der Ent, Grietje Molema, David Ginsburg, Kristina L. Hunker, William C. Aird, Audrey C. A. Cleuren, Santhi K. Ganesh, Hui Jiang, Andrew Yee, David R. Siemieniak
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 116(47), 23618-23624. NATL ACAD SCIENCES
Proc Natl Acad Sci U S A
Proc Natl Acad Sci U S A
Endothelial cells (ECs) are highly specialized across vascular beds. However, given their interspersed anatomic distribution, comprehensive characterization of the molecular basis for this heterogeneity in vivo has been limited. By applying endotheli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3844edf4e9540fe28c17ded36731085
https://doi.org/10.1101/708701
https://doi.org/10.1101/708701
Autor:
Paula Marttinen, Brendan J. Battersby, Eija Jokitalo, Cecilia Mancini, Tuula A. Nyman, Sara Seneca, Fumi Suomi, Anu Suomalainen, Helena Vihinen, Taina Turunen, Christopher B. Jackson, Uwe Richter, Anne Lombès, Kah Ying Ng, Alfredo Brusco, James B. Stewart, Marita A Isokallio, Robert W. Taylor
Publikováno v:
Life Sci Alliance
Life Science Alliance
Life Science Alliance
Quality control defects of mitochondrial nascent chain synthesis trigger a sequential stress response characterized by OMA1 activation and ribosome decay, determining mitochondrial form and function.
Mitochondria have a compartmentalized gene ex
Mitochondria have a compartmentalized gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb791ad5c28fb97e1358e6dbc9a5d10f
http://hdl.handle.net/10138/307109
http://hdl.handle.net/10138/307109
Autor:
Jörn Dengjel, Verónica I. Dumit, Lea Bühler, Carole Roubaty, Martin Schwemmle, Shadi Abou-Eid, Christine Gretzmeier, Monique Gannagé, Zehan Hu, Stéphanie Kaeser-Pebernard, Andrea C. Becker, Christian Münz, Sebastian Giese, Petra Paul
Publikováno v:
Mol Cell Proteomics, vol. 17, no. 10, pp. 1909-1921
Molecular & Cellular Proteomics : MCP
Molecular & Cellular Proteomics : MCP
Seasonal epidemics of influenza A virus are a major cause of severe illness and are of high socio-economic relevance. For the design of effective antiviral therapies, a detailed knowledge of pathways perturbed by virus infection is critical. We perfo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b836ddff6ce1f7f577757ebf89952c
https://www.zora.uzh.ch/id/eprint/165546/
https://www.zora.uzh.ch/id/eprint/165546/
Autor:
Violeta Castelo-Szekely, Mara De Matos, Marina Tusup, Steve Pascolo, Jernej Ule, David Gatfield
Publikováno v:
Nucleic acids research, vol. 47, no. 10, pp. 5193-5209
Nucleic Acids Research
Nucleic Acids Research
The non-canonical initiation factor DENR promotes translation reinitiation on mRNAs harbouring upstream open reading frames (uORFs). Moreover, DENR depletion shortens circadian period in mouse fibroblasts, suggesting involvement of uORF usage and rei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4516f910ea64a2e106c7171aa9612f9