Zobrazeno 1 - 10
of 334
pro vyhledávání: '"Ribosome stalling"'
Publikováno v:
Applied Microbiology, Vol 4, Iss 3, Pp 1335-1347 (2024)
Background: Elongation factor protein (EF-P) in bacteria helps ribosomes to incorporate contiguous proline residues (xPro) into proteins. In this way, EF-P rescues ribosomes from stalling at these xPro motifs. Whereas EF-P deficiency is lethal for so
Externí odkaz:
https://doaj.org/article/bb2f365bf30f42bf858d8d79910b5b1b
Autor:
Ramona Weber, Chung-Te Chang
Publikováno v:
eLife, Vol 13 (2024)
Recent findings indicate that the translation elongation rate influences mRNA stability. One of the factors that has been implicated in this link between mRNA decay and translation speed is the yeast DEAD-box helicase Dhh1p. Here, we demonstrated tha
Externí odkaz:
https://doaj.org/article/a6b75c2983af43c18646c39b82b16dd2
Autor:
Eva Martin-Solana, Irene Diaz-Lopez, Yamina Mohamedi, Ivan Ventoso, Jose-Jesus Fernandez, Maria Rosario Fernandez-Fernandez
Publikováno v:
Neurobiology of Disease, Vol 195, Iss , Pp 106488- (2024)
Given their highly polarized morphology and functional singularity, neurons require precise spatial and temporal control of protein synthesis. Alterations in protein translation have been implicated in the development and progression of a wide range
Externí odkaz:
https://doaj.org/article/1c6a58c940e74cd48db0cbbcab08e5a8
Autor:
Sophie Vazulka, Matteo Schiavinato, Christopher Tauer, Martin Wagenknecht, Monika Cserjan-Puschmann, Gerald Striedner
Publikováno v:
Microbial Cell Factories, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Background Escherichia coli is a cost-effective expression system for production of antibody fragments like Fabs. Various yield improvement strategies have been applied, however, Fabs remain challenging to produce. This study aimed to charac
Externí odkaz:
https://doaj.org/article/9ce5eca01df347008b23ab60394952a4
Publikováno v:
RNA Biology, Vol 20, Iss 1, Pp 348-358 (2023)
RNA is integral to gene expression as messenger RNA (mRNA), transfer RNA (tRNA) and ribosomal RNA (rRNA) each play roles to transmit information from DNA into synthesis of functional proteins. During their lifespan, these nucleic acids may be chemica
Externí odkaz:
https://doaj.org/article/bc55a13d74a94cc698e22d712d74ea7f
Autor:
Hana Sahinbegovic, Alexander Vdovin, Renata Snaurova, Michal Durech, Jakub Nezval, Jiri Sobotka, Roman Hajek, Tomas Jelinek, Michal Simicek
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 8, Pp 6717-6727 (2023)
Gene expression is a fundamental process that enables cells to produce specific proteins in a timely and spatially dependent manner. In eukaryotic cells, the complex organization of the cell body requires precise control of protein synthesis and loca
Externí odkaz:
https://doaj.org/article/c556eb38632c44e789243d0b48695f9c
Akademický článek
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Publikováno v:
BMC Microbiology, Vol 22, Iss 1, Pp 1-13 (2022)
Abstract Background Ribosome stalling on ermBL at the tenth codon (Asp) and mRNA stabilization are believed to be mechanisms by which erythromycin (Ery) induces ermB expression. Expression of ermB is also induced by 16-membered ring macrolides (tylos
Externí odkaz:
https://doaj.org/article/3e6914f8447e46c9bf19c5a07ce06fd5
Publikováno v:
Frontiers in Molecular Biosciences, Vol 9 (2023)
Proteins are versatile molecular machines that control and execute virtually all cellular processes. They are synthesized in a multilayered process requiring transfer of information from DNA to RNA and finally into polypeptide, with many opportunitie
Externí odkaz:
https://doaj.org/article/63c04da41af94a6fa2337b5c9cb763bb
Akademický článek
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