Zobrazeno 1 - 10
of 2 857
pro vyhledávání: '"Ribosome inactivating protein"'
Targeting hexokinase 2 to enhance anticancer efficacy of trichosanthin in HeLa and SCC25 cell models
Publikováno v:
ADMET and DMPK (2024)
Background and purpose: Trichosanthin (TCS) is a plant-based ribosome-inactivating protein exhibiting a range of pharmacological properties, including abortifacient and anticancer. However, the routine clinical use in cancer treatment was hampered by
Externí odkaz:
https://doaj.org/article/495bce991b3645db80e566bf38c07f7b
Autor:
Simin Chen, Noémie De Zutter, Anikó Meijer, Koen Gistelinck, Pieter Wytynck, Isabel Verbeke, Vinicius J. S. Osterne, Subramanyam Kondeti, Tim De Meyer, Kris Audenaert, Els J. M. Van Damme
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Ribosome-inactivating proteins (RIPs) are plant enzymes that target the rRNA. The cytoplasmic RIP, called OsRIP1, plays a crucial role in regulating jasmonate, a key plant hormone. Understanding the role of OsRIP1 can provide insights into enhancing
Externí odkaz:
https://doaj.org/article/86e09e515e8b49de8a7285fe0bff4793
Publikováno v:
Toxins, Vol 16, Iss 10, p 440 (2024)
Malanin is a new type II ribosome-inactivating protein (RIP) purified from Malania oleifera, a rare, endangered tree is only found in the southwest of Guangxi Province and the southeast of Yunnan Province, China. The gene coding sequence of malanin w
Externí odkaz:
https://doaj.org/article/44eb97d4150b4082986e64d33f09ba1d
Autor:
Lucía Citores, Sara Ragucci, Claudia C. Gay, Rosita Russo, Angela Chambery, Antimo Di Maro, Rosario Iglesias, José M. Ferreras
Publikováno v:
Toxins, Vol 16, Iss 4, p 185 (2024)
Ribosome-inactivating proteins (RIPs) are a group of proteins with rRNA N-glycosylase activity that irreversibly inhibit protein synthesis and consequently cause cell death. Recently, an RIP called ledodin has been found in shiitake; it is cytotoxic,
Externí odkaz:
https://doaj.org/article/ef1cd3c36f8441f19690f6d907ec271c
Publikováno v:
Toxins, Vol 16, Iss 4, p 192 (2024)
The control of crop diseases caused by fungi remains a major problem and there is a need to find effective fungicides that are environmentally friendly. Plants are an excellent source for this purpose because they have developed defense mechanisms to
Externí odkaz:
https://doaj.org/article/5b0494588a6a439980e2f6baf612b0e8
Autor:
Monika Novak Babič, Sara Ragucci, Adrijana Leonardi, Miha Pavšič, Nicola Landi, Igor Križaj, Nina Gunde-Cimerman, Kristina Sepčić, Antimo Di Maro
Publikováno v:
Biomolecules, Vol 14, Iss 3, p 336 (2024)
Sodin 5 is a type 1 ribosome-inactivating protein isolated from the seeds of Salsola soda L., an edible halophytic plant that is widespread in southern Europe, close to the coast. This plant, known as ‘agretti’, is under consideration as a new po
Externí odkaz:
https://doaj.org/article/1591c3bda9f7450598abeb486d847a44
Autor:
Reza Maleki, Libing Fu, Ricardo Sobhie Diaz, Francisco Eduardo Gontijo Guimarães, Otávio Cabral-Marques, Gustavo Cabral-Miranda, Mohammad Sadraeian
Publikováno v:
J, Vol 6, Iss 1, Pp 85-101 (2023)
Pulchellin is a plant biotoxin categorized as a type 2 ribosome-inactivating protein (RIPs) which potentially kills cells at very low concentrations. Biotoxins serve as targeting immunotoxins (IT), consisting of antibodies conjugated to toxins. ITs h
Externí odkaz:
https://doaj.org/article/ddfa876402984c8e99fe19f5809a5402
Akademický článek
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Akademický článek
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Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
Plant suspension cells were treated with recombinant OsRIP1, a type 1 ribosome-inactivating protein (RIP) from rice (Oryza sativa L.). OsRIP1 triggered cell death in tobacco BY-2 cells but not in Arabidopsis PSB-D cells. Phenotypic changes in BY-2 ce
Externí odkaz:
https://doaj.org/article/df848d27913143d594ca0fa9339d7957