Výsledky vyhledávání - "Ribosomal protein S19"

Daptomycin suppresses tumor migration and angiogenesis via binding to ribosomal protein S19 in humans

Autor: Peter Karuso, Ho Jeong Kwon, Hwa Jung Lee, Sung Min Cho

Publikováno v: The Journal of Antibiotics. 74:726-733

We have previously reported that daptomycin (DAP), a last resort antibiotic, binds to ribosomal protein S19 (RPS19) in humans and exhibits selective anti-cancer activity against MCF7 breast cancer cells. Here, we investigated the role of RPS19 in the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3fa940bd308834cca43ff2b6edb01e
https://doi.org/10.1038/s41429-021-00446-x

Zobrazit plný text záznamu

1H, 13C, 15N backbone and side-chain NMR assignments of the C-terminal domain of Mycobacterium Tuberculosis ribosome maturation factor RimM

Autor: Donghai Lin, Chenyun Guo, Haoran Zhang

Publikováno v: Biomolecular NMR Assignments. 15:373-377

Tuberculosis (TB), a lethal disease caused by Mycobacterium tuberculosis (Mtb) infection, develops multidrug-resistance and needs new drugs for effective treatment. As a ribosome maturation factor protein, RimM plays an essential role in the bacteria

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a44f304475c65dc7b2e9108c00c1d365
https://doi.org/10.1007/s12104-021-10032-9

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

A Case Report of Diamond-Blackfan Anaemia with RPS19 Mutation

Autor: Quazi Smita Haque, Abu Jafar Mohammed Saleh, Sazzad Zayed Chowdhury, Md. Maruf Al Hasan, Muhammad Shahidul Islam Sikder, Masba Uddin Chowdhury

Publikováno v: Haematology Journal of Bangladesh. 5:37-41

Diamond Blackfan Anaemia (DBA) is a rare disorder which presents with anaemia in early childhood. This heterogenous disorder is mainly autosomal dominantly inherited. Significantproportions of the cases are associated with craniofacial anomalies and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::84ccd16d0d68a7e2898494f0301e24ef
https://doi.org/10.37545/haematoljbd202167

Zobrazit plný text záznamu

Successful gene therapy of Diamond-Blackfan anemia in a mouse model and human CD34+ cord blood hematopoietic stem cells using a clinically applicable lentiviral vector

Autor: Yang Liu, Maria Dahl, Johan Flygare, Axel Schambach, Shubhranshu Debnath, Sarah Warsi, Stefan Karlsson, Tan Hooi Min Grahn, Emma Smith, Jun Chen, Michael Rothe

Publikováno v: Haematologica. 107:446-456

Diamond-Blackfan anemia (DBA) is an inherited bone marrow failure disorder in which pure red blood cell aplasia is associated with physical malformations and a predisposition to cancer. Twentyfive percent of patients with DBA have mutations in a gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2c6f20921559b4d864a2b33a72ec0673
https://doi.org/10.3324/haematol.2020.269142

Zobrazit plný text záznamu

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Akademický článek

Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Hantaviruses use the endogenous host factor P58IPK to combat the PKR antiviral response

Autor: Lei lin, Qiming Li, Mohammad A. Mir, Austin D. Royster, Zekun Wang, Songyang Ren, Safder S. Ganaie, Jianming Qiu, Sichen Liu, Sheema Mir

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 17, Iss 10, p e1010007 (2021)

Hantavirus nucleocapsid protein (NP) inhibits protein kinase R (PKR) dimerization by an unknown mechanism to counteract its antiviral responses during virus infection. Here we demonstrate that NP exploits an endogenous PKR inhibitor P58IPK to inhibit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c03c06ff1b081a88afaab40019f8577d
https://pubmed.ncbi.nlm.nih.gov/34653226

Zobrazit plný text záznamu

Structural Basis for the C-Terminal Domain of Mycobacterium Tuberculosis Ribosome Maturation Factor RimM to Bind Ribosomal Protein S19

Autor: Liubin Feng, Haoran Zhang, Xinli Liao, Qiuxiang Zhou, Donghai Lin, Huilin Wang, Chenyun Guo

Publikováno v: Biomolecules, Vol 11, Iss 597, p 597 (2021)
Biomolecules
Volume 11
Issue 4

Multidrug-resistant tuberculosis (TB) is a serious threat to public health, calling for the development of new anti-TB drugs. Chaperon protein RimM, involved in the assembly of ribosomal protein S19 into 30S ribosomal subunit during ribosome maturati

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca0794286848fc6ed20f6bb7fd6e512e
https://www.mdpi.com/2218-273X/11/4/597

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání