Výsledky vyhledávání - "Ribosomal/genetics"

Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT-RNR1 Genotype

Autor: Cristina Rodríguez-Antona, Rachel Huddart, Keito Hoshitsuki, Teri E. Klein, Richard J.H. Smith, Joshua Wolf, Michelle Whirl-Carrillo, William G. Newman, Kelly E. Caudle, John H McDermott, Peter S. Steyger, Neal Cody

Publikováno v: Clin Pharmacol Ther
McDermott, J H, Wolf, J, Hoshitsuki, K, Huddart, R, Caudle, K E, Whirl-Carrillo, M, Steyger, P S, Smith, R J H, Cody, N, Rodriguez-Antona, C, Klein, T E & Newman, W G 2022, ' Clinical Pharmacogenetics Implementation Consortium Guideline for the Use of Aminoglycosides Based on MT-RNR1 Genotype ', Clinical Pharmacology and Therapeutics, vol. 111, no. 2, pp. 366-372 . https://doi.org/10.1002/cpt.2309

Aminoglycosides are widely used antibiotics with notable side effects such as nephrotoxicity, vestibulotoxicity and sensorineural hearing loss (cochleotoxicity). MT-RNR1 is a gene that encodes the 12s rRNA subunit and is the mitochondrial homologue o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39bd4873a4dd7b574d04ec999d94d0ea
https://pubmed.ncbi.nlm.nih.gov/34032273

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Influenza A virus infection impacts systemic microbiota dynamics and causes quantitative enteric dysbiosis

Autor: Beryl Mazel-Sanchez, Mirco Schmolke, Soner Yildiz, Matheswaran Kandasamy, Balaji Manicassamy

Publikováno v: Microbiome, Vol 6, Iss 1, Pp 1-17 (2018)
Microbiome, Vol. 6, No 1 (2018) P. 9
Microbiome

Background Microbiota integrity is essential for a growing number of physiological processes. Consequently, disruption of microbiota homeostasis correlates with a variety of pathological states. Importantly, commensal microbiota provide a shield agai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::813ddff2584066e40dca843130900403
http://link.springer.com/article/10.1186/s40168-017-0386-z

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Virulence and antifungal susceptibility of microsatellite genotypes of Candida albicans from superficial and deep locations

Autor: Weizheng Ou, Maoning Xia, Abdullah M. S. Al-Hatmi, Chenggang Zou, Xie Zhi, Andriy A. Sibirny, Yu Cao, Sybren de Hoog, Feng-Yan Bai, Liang Zhao, Meizhu Wang, Yanyan Wang, Wanqing Liao, Yingqian Kang

Publikováno v: Yeast (Chichester, England)
Yeast (Chichester, England), 36(5), 363-373. John Wiley and Sons Ltd

A set of 185 strains of Candida albicans from patients with vulvovaginal candidiasis (VVC) and from non‐VVC clinical sources in southwest China was analysed. Strains were subjected to genotyping using CAI microsatellite typing and amplification of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904101bf1b2efedd8e400aa01ce491ce
https://pubmed.ncbi.nlm.nih.gov/31037772

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A metagenomic study of the gut microbiome in Behcet's disease

Autor: Qingfeng Cao, Qian Xu, Ni Zhang, Yue He, Xiao Xiong, Peizeng Yang, Xinyuan Zhang, Liping Du, Aize Kijlstra, Qingfeng Wang, Nan Qin, Shengping Hou, Jihong Tang, Xinyue Huang, Zi Ye, Chunjiang Zhou, Chunyan Wu

Publikováno v: Microbiome
Microbiome, 6:135. BioMed Central Ltd
Microbiome, Vol 6, Iss 1, Pp 1-13 (2018)

Background Behcet’s disease (BD) is a recalcitrant, multisystemic inflammatory disease that can lead to irreversible blindness. Microbial agents have been considered to contribute to the pathogenesis of this disease, but the underlying mechanisms r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6970e8f53de9901c6bc6ee035d0f5eb0
https://doi.org/10.1186/s40168-018-0520-6

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Crawling-induced floor dust resuspension affects the microbiota of the infant breathing zone

Autor: Pirkka V. Kirjavainen, Martin Täubel, Balamuralikrishna Jayaprakash, Sampo Saari, Anne Hyvärinen, Rauno Holopainen, Brandon E. Boor, Heidi Hyytiäinen, Kaarle Hämeri, Jorma Keskinen

Publikováno v: Microbiome, Vol 6, Iss 1, Pp 1-12 (2018)
Microbiome
Hyytiäinen, H K, Jayaprakash, B, Kirjavainen, P V, Saari, S E, Holopainen, R, Keskinen, J, Hämeri, K, Hyvärinen, A, Boor, B E & Täubel, M 2018, ' Crawling-induced floor dust resuspension affects the microbiota of the infant breathing zone ', Microbiome, vol. 6, no. 1, 25 . https://doi.org/10.1186/s40168-018-0405-8

Background Floor dust is commonly used for microbial determinations in epidemiological studies to estimate early-life indoor microbial exposures. Resuspension of floor dust and its impact on infant microbial exposure is, however, little explored. The

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https://trepo.tuni.fi/handle/10024/126470

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Use of shotgun metagenomics for the identification of protozoa in the gut microbiota of healthy individuals from worldwide populations with various industrialization levels

Autor: Laure Ségurel, Eric Viscogliosi, Nausicaa Gantois, Alain Froment, Amandine Cian, Magali Chabé, Ana Lokmer

Publikováno v: PLoS ONE
PLoS ONE, 2019, 14 (2), pp.e0211139. ⟨10.1371/journal.pone.0211139⟩
PLoS ONE, Public Library of Science, 2019, 14 (2), pp.e0211139. ⟨10.1371/journal.pone.0211139⟩
PLoS ONE, Vol 14, Iss 2, p e0211139 (2019)

International audience; Protozoa have long been considered undesirable residents of the human gut, but recent findings suggest that some of them may positively affect the gut ecosystem. To better understand the role and ecological dynamics of these c

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https://doi.org/10.1371/journal.pone.0211139

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Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins

Autor: Sandya Subramanian, Erika Shor, Timothy Hoggard, Michael Weinreich, Edel M. Hyland, Fu-Jung Chang, Jessica Kenworthy, Catherine A. Fox, Jef D. Boeke, Julie Chueng, Kelsey Rae Perry

Publikováno v: PLoS Genetics, Vol 14, Iss 5, p e1007418 (2018)
Hoggard, T A, Chang, F, Perry, K R, Subramanian, S, Kenworthy, J, Chueng, J, Shor, E, Hyland, E M, Boeke, J D, Weinreich, M & Fox, C A 2018, ' Yeast heterochromatin regulators Sir2 and Sir3 act directly at euchromatic DNA replication origins ', PLoS Genetics, vol. 14, no. 5, pp. e1007418 . https://doi.org/10.1371/journal.pgen.1007418
PLoS Genetics

Most active DNA replication origins are found within euchromatin, while origins within heterochromatin are often inactive or inhibited. In yeast, origin activity within heterochromatin is negatively controlled by the histone H4K16 deacetylase, Sir2,

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http://europepmc.org/articles/PMC5991416?pdf=render

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Microbial metagenome of urinary tract infection

Autor: J. Craig Venter, William H. Biggs, Amalio Telenti, Yanbao Yu, Manolito Torralba, Rembert Pieper, Karen E. Nelson, Weizhong Li, Harinder Singh, Kelvin J. Moncera, Ahmed A. Moustafa, Oriol Manuel

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-12 (2018)
Scientific reports, vol. 8, no. 1, pp. 4333
Scientific Reports

Urine culture and microscopy techniques are used to profile the bacterial species present in urinary tract infections. To gain insight into the urinary flora in infection and health, we analyzed clinical laboratory features and the microbial metageno

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afb24e1b80e023a353d924816e1f30b2
https://doi.org/10.1038/s41598-018-22660-8

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